Deck 21: Drugs Used to Affect Mens Health

Question 1

Which of the following statements regarding neuronal response in the initiation of an erection is true?

A)It is a primarily parasympathetic response.
B)It is a sympathetic response.
C)It is not important in initiation of erection.
D)It is a serotonergic response that initiates erections.

Answer 1

It is a primarily parasympathetic response.

Question 2

Which statement regarding men's health in the United States is true?

A)The average life expectancy of a male born in 2010 is 81 years.
B)Life expectancy for men and women are the same.
C)Women take more health risks than men.
D)Male patients often are hesitant to bring health concerns to their medical providers.

Answer 2

Male patients often are hesitant to bring health concerns to their medical providers.

Question 3

Which of the following best describes the duration of effect for tadalafil (Cialis)?

A)36 hours
B)4 hours
C)12 hours
D)90 minutes

Answer 3

36 hours

Question 4

The presence of food most significantly inhibits the absorption of which PDE5 inhibitor?

A)sildenafil (Viagra)
B)tadalafil (Cialis)
C)vardenafil (Levitra)
D)alprostadil (Muse)

Question 5

All of the following are nonselective alpha-one blockers except:

A)doxazosin (Cardura)
B)prazosin (Minipress)
C)terazosin (Hytrin)
D)tamsulosin (Flomax)

Question 6

This adverse effect of the alpha blockers requires such medications to be started at the lowest dose.

A)Orthostatic hypotension
B)Bleeding
C)Hypersensitivity
D)Flu-like symptoms

Question 7

Which of the following statements regarding BPH treatment with alpha-one blockers is false?

A)Alpha-one blockers should result in a relatively rapid (1-month)response.
B)Alpha blockers relax smooth muscles in the prostate gland.
C)Alpha-one blockers can lower blood pressure.
D)Alpha-one blockers can shrink the size of the prostate.

Question 8

According to the Massachusetts Male Aging Study (MMAS),what percentage of males aged 40 to 70 years has had some degree of ED?

A)20%
B)35%
C)52%
D)75%

Question 9

What is the role of cyclic guanosine monophosphate (cGMP)in erectile function?

A)Activates a specific protein kinase,leading to smooth muscle relaxation
B)Causes release of vasoconstrictor substances
C)Causes release of androgens from adrenals
D)Activates enzymes,which convert estrogen into testosterone

Question 10

Which of the following PDE5 inhibitors is approved at a low dose for daily use?

A)sildenafil (Viagra)
B)tadalafil (Cialis)
C)vardenafil (Levitra)
D)alprostadil (Muse)

Question 11

Which of the following medications is slow to show effect,requiring up to 6 months to reach maximum benefit,but can shrink the size of the prostate and show benefits in affecting the clinical course and progression of BPH?

A)dutasteride (Avodart)
B)alfuzosin (Uroxatral)
C)doxazosin (Cardura)
D)tamsulosin (Flomax)

Question 12

Which of the following ED drugs is most selective for PDE5?

A)sildenafil (Viagra)
B)tadalafil (Cialis)
C)vardenafil (Levitra)
D)alprostadil (Muse)

Question 13

The most common adverse effect of PGE1 (Caverject)is:

A)Penile pain or discomfort.
B)Diarrhea.
C)Visual and hearing deficits.
D)Hypotension.

Question 14

Signs and symptoms of benign prostatic hypertrophy (BPH)include all of the following except:

A)Hematuria.
B)Weak urinary stream.
C)Urinary hesitancy.
D)Nocturia.
E)Straining to void.

Question 15

Which of the following statements regarding PDE1 (Caverject)medication for ED is true?

A)It is injected into the base of the penis prior to intercourse.
B)It lasts for 24 hours.
C)Onset of action is 1 to 2 hours.
D)It is effective in 60% to 75% of males.
E)It is not effective for neurogenic causes of ED.

Question 16

Medications account for what percentage of ED?

A)25%
B)10%
C)50%
D)75%

Question 17

The 5-alpha reductase inhibitors work by which mechanism?

A)Inhibit aromatase enzymes and affect androgen levels
B)Inhibit the conversion of testosterone to dihydrotestosterone (DHT)
C)Inhibit LH production by the anterior pituitary gland
D)Block androgen receptors on prostate tissue

Question 18

Which of the following is a 5-alpha reductase inhibitor used for the treatment of BPH?

A)dutasteride (Avodart)
B)alfuzosin (Uroxatral)
C)doxazosin (Cardura)
D)tamsulosin (Flomax)

Question 19

Which of the following statements regarding phosphodiesterase type 5 (PDE5)inhibitors and treatment of ED is true?

A)Priapism is more common with oral PDE5 inhibitors than alprostadil.
B)Insurance companies will pay for daily use of PDE5 inhibitors.
C)When patients do not respond to PDE5 inhibitors due to cord injury or innervations damage,alprostadil (Caverject)can be used.
D)Nitrates are safe to take with PDE5 inhibitors.

Question 20

The most common cause of vasculogenic ED is:

A)Atherosclerosis
B)Venous anatomical abnormalities
C)Low testosterone
D)Prostate disease
E)Coagulopathy

Question 21

More than one-half of all men who seek medications for ED have which of the following conditions?

A)Acne
B)Diabetes
C)Hair loss
D)Depression

Question 22

Acute bacterial prostatitis should be treated with antibiotics for how long?

A)7 days
B)14 days
C)30 days
D)12 weeks

Question 23

The primary cause of male hypogonadism is:

A)Aging.
B)Genetic defects.
C)Pituitary disease.
D)Hypothalamic failure.
E)Thyroid disease.

Question 24

The least appropriate form of testosterone replacement therapy is:

A)Testosterone gels.
B)IM testosterone preparations.
C)Oral testosterone tablets.
D)Testosterone patches.

Question 25

How long after using minoxidil (Rogaine)may a man donate blood and be assured that he is not transferring a teratogenic agent to a pregnant mother?

A)2 weeks
B)1 month
C)3 months
D)6 months

Question 26

Patients using minoxidil (Rogaine)for hair regrowth will find that it takes how long to see any significant improvement?

A)1 to 2 weeks
B)1 month
C)2 to 3 months
D)6 months to 1 year

Question 27

A common misperception about all drugs used for ED is:

A)They are relatively expensive.
B)They protect against sexually transmitted diseases.
C)An erection lasting more than 4 hours is normal.
D)They should not be used if the partner is pregnant.

Question 28

For men ages 14 to 35 years who develop epididymitis,the most likely cause is:

A)Neisseria gonorrhoeae or Chlamydia trachomatis.
B)Escherichia coli.
C)Enterococcus faecalis.
D)Proteus vulgaris.

Question 29

Which of the following statements regarding testosterone therapy is true?

A)Testosterone can decrease red blood cell mass and cause anemia.Hematocrit must be monitored.
B)Testosterone should be offered to aging men to improve libido and declining muscle strength and mass.
C)Testosterone replacement therapy has been conclusively identified as a cause of prostate cancer.
D)Urinalysis and digital rectal examinations should be performed regularly in patients taking testosterone.

Question 30

Which of the following drugs is a medication used topically for male-pattern baldness?

A)minoxidil (Rogaine)
B)finasteride (Propecia)
C)alprostadil
D)alfuzosin (Uroxatral)

Question 31

Which of the following medications for the treatment of male-pattern baldness is taken orally?

A)prazosin (Minipress)
B)doxazosin (Cardura)
C)alfuzosin (Uroxatral)
D)finasteride (Propecia)

Question 32

In general,there are few,if any,side effects with the use of ED drugs,but two notable exceptions are:

A)Constipation and abdominal pain
B)Rash and diarrhea
C)Headache and facial flushing
D)Diarrhea and abdominal pain

Question 33

For the past 30 years,the FDA has approved six drugs for the treatment of BPH.Which class relaxes smooth muscles in the prostate gland?

A)Alpha blockers
B)5-alpha reductase inhibitors.
C)Calcium channel blockers
D)Angiotensin-converting enzyme inhibitors

Question 34

A conscientious clinician will usually limit a prescription for ED drugs to which of the following?

A)4 to 10 tablets per month
B)30 tablets
C)90 tablets
D)6-month supply

Question 35

Finasteride (Proscar)has a half-life of about 6 to 8 hours,depending on the age of the patient;dutasteride (Avodart)has a half-life of approximately 4 weeks,but patients should be counseled that the onset of any positive clinical effects from both medications may take how long?

A)1 to 2 weeks of therapy
B)1 to 2 months of therapy
C)3 to 6 months of therapy
D)More than 6 months of therapy

Question 36

Common contraindications for ED drugs are that they should not be given to anybody with a cardiovascular disease (such as congestive heart failure and hypertension).However,they should also not be given to patients who have which of the following conditions?

A)Diabetes
B)Scoliosis
C)Osteoarthritis
D)Retinosa pigmentosa

Question 37

If a patient is taking a calcium channel blocker,such as amlodipine,for hypertension and is also given a PDE5 agent,such as tadalafil (Cialis),for ED,which of the following effects may occur?

A)A small additive drop in blood pressure
B)A small increase in blood pressure
C)Exaggeration of glaucoma symptoms
D)Increased chance of urticaria

Question 38

Which of the following should a physician assume,if present,will aggravate symptoms of BPH?

A)Any other medication
B)Diabetes mellitus
C)Hypertension
D)Congestive heart failure
E)All of the above