Deck 14: Drugs Used to Treat Common Neurological Conditions

Question 1

Prescription sleep aids act on which receptors?

A)Adrenocorticotropic hormone receptor (ACTH)receptors
B)GABA receptors
C)Choline receptors
D)Dopamine receptors

Answer 1

GABA receptors

Question 2

Patients with a lack of serotonin can suffer from which of the following?

A)Decreased appetite
B)Depression
C)Inflammatory bowel syndrome
D)Decreased need for sleep

Answer 2

Depression

Question 3

Which of the following is the most abundant inhibitory neurotransmitter in the brain?

A)ACH
B)Endorphins
C)Dopamine
D)Gamma-aminobutyric acid (GABA)

Answer 3

Gamma-aminobutyric acid (GABA)

Question 4

Which of the following are released from the adrenal glands as part of the "fight-or-flight" reflex at times of stress?

A)Norepinephrine and epinephrine
B)Serotonin and dopamine
C)GABA and norepinephrine
D)Epinephrine and serotonin

Question 5

ACh is responsible for which of the following?

A)Auditory control
B)Rapid eye movement
C)Constipation
D)Olfactory control

Question 6

Prescription sleep aids are excreted via:

A)Liver.
B)Skin.
C)Kidneys.
D)Feces.

Question 7

Drugs that enhance release of acetylcholine (ACh)or inhibit its destruction (such as acetylcholinesterase inhibitors [AChEIs])are useful in the treatment of which of the following diseases?

A)Alzheimer's disease
B)Huntington disease
C)Crohn's disease
D)Lyme disease

Question 8

Succinimides are classified under which pregnancy risk category?

A)Category A
B)Category B
C)Category C
D)Category D

Question 9

Coadministration of anorexiants and which of the following can cause hypertensive crisis?

A)Alcohol
B)Monamine oxidase inhibitors (MAOIs)
C)Selective serotonin reuptake inhibitors (SSRIs)
D)Insulin

Question 10

What is the typical dose for gabapentin (Neurontin)?

A)100 mg TID
B)200 mg TID
C)300 mg TID
D)400 mg TID

Question 11

Grand mal seizures are also known as:

A)Tonic-clonic seizures
B)Absence seizures
C)Febrile seizures
D)Simple partial seizures

Question 12

Which of the following is an action of endorphins?

A)Increased pain
B)Increased respiration
C)Slowed heart rate
D)Elevated blood pressure

Question 13

In which of the following diseases is there typically a deficiency in dopamine?

A)Alzheimer's disease
B)Wilson's disease
C)Parkinson's disease
D)Multiple sclerosis

Question 14

Which drug should be administered immediately when treating status epilepticus?

A)lorazepam (Ativan)
B)carbamazepine (Tegretol)
C)oxcarbazepine (Trileptal)
D)phenytoin (Dilantin)

Question 15

Which of the following medications can change urine to a brown color and cause a serious skin rash and gingival hyperplasia?

A)methadone
B)levodopa
C)sulfonylureas
D)hydantoins

Question 16

Which of the following foods can interact with iminostilbenes,causing serum drug levels of these drugs to increase?

A)Apples
B)Bananas
C)Kiwi
D)Grapefruit

Question 17

Which of the following is an adverse reaction of anorexiants?

A)Miosis
B)Priapism
C)Tachycardia
D)Drooling

Question 18

Prescription sleep aids can be habit forming;therefore they should be used no longer than:

A)10 days.
B)15 days.
C)20 days.
D)25 days.

Question 19

Which of the following drugs has a U.S.Federal Drug Administration (FDA)black box warning due to its potential to cause life-threatening blood dyscrasias?

A)carbamazepine (Tegretol)
B)barbiturates
C)ethanol
D)levodopa

Question 20

Appetite suppressants have a long history of abuse;therefore;they are placed into which of the following categories under the Controlled Substances Act?

A)Schedule I
B)Schedule II
C)Schedule III
D)Schedule IV

Question 21

Selegiline (Eldypryl)should not be given with which of the following?

A)Levodopa/carbidopa
B)Bromocriptine
C)SSRIs
D)Tolcapone (Tasmar)

Question 22

On-off syndrome is a complication typically appearing after 2 or more years of which type of Parkinson's disease medications?

A)Anticholinergic agents
B)MAO-B inhibitors
C)Levodopa
D)Catechol-O-methyltransferase inhibitors

Question 23

Levodopa/carbidopa has been associated with which of the following?

A)Malignant melanoma
B)Basel cell carcinoma
C)Squamous cell carcinoma
D)Actinic keratosis

Question 24

Triptans should not be administered with which of the following?

A)Proton pump inhibitors
B)Penicillin
C)SSRIs
D)NSAIDs

Question 25

Which of the following medication classes used to treat Parkinson's disease has relaxing effects on smooth musculature both directly and indirectly through parasympathetic nervous system inhibition?

A)Decarboxylase inhibitor
B)L-Dopa
C)Anticholinergics
D)MAO-B inhibitor

Question 26

Ergotamines are classified under which pregnancy risk category?

A)Category B
B)Category C
C)Category D
D)Category X

Question 27

Which of the following is the therapeutic range for the iminostilbenes?

A)4 to 8 mcg/mL
B)4 to 10 mcg/mL
C)4 to 12 mcg/mL
D)4 to 14 mcg/mL

Question 28

The serotonin receptor agonists are also called the:

A)-mycins.
B)-triptans.
C)-haptens.
D)-cyclines.

Question 29

Which of the following drugs can be given orally,subcutaneously,or intranasally?

A)sumatriptan (Imitrex)
B)zolmitriptan (Zomig)
C)rizatriptan (Maxalt)
D)almotriptan (Axert)

Question 30

Which of the following acetylcholinesterase inhibitors requires monitoring of alanine aminotransferase (ALT)because of the risk of hepatotoxicity?

A)donepezil (Aricept)
B)tacrine (Cognex)
C)galantamine (Razadyne)
D)rivastigmine (Excelon)

Question 31

Which of the following dopamine agonists is used to treat Parkinson's disease as well as restless leg syndrome?

A)bromocriptine (Parlodel)
B)pergolide (Permax)
C)ropinerol (Requip)
D)Tolcapone (Tasmar)

Question 32

Succinimides are metabolized via the:

A)Liver.
B)Small bowel.
C)Large bowel.
D)Kidney.

Question 33

Patients should be advised to use nonbenzodiazepine hypnotics (sleep agents)as routine treatment of insomnia for no longer than:

A)10 days.
B)30 days.
C)60 days.
D)90 days.

Question 34

Which of the following acetylcholinesterase inhibitors should be taken 5 mg daily at night for 1 week and if tolerated may be taken 10 mg/day?

A)donepezil (Aricept)
B)tacrine (Cognex)
C)galantamine (Razadyne)
D)rivastigmine (Excelon)

Question 35

Which drug is primarily used for essential tremors in adults?

A)primidone (Mysoline)
B)clonazepam (Klonapin)
C)felbamate (Felbatol)
D)lamotrigine (Lamictal)

Question 36

Clinicians should monitor intraocular pressure (IOP)in patients taking which of the following Parkinson's medications?

A)levodopa/carbidopa
B)benztropine (Cogentin)
C)bromocriptine (Parlodel)
D)pramipexole (Mirapex)

Question 37

What is the maximum amount of sumatriptan (Imitrex)(25 mg,50 mg,or 100 mg tablets)that can be given in one day?

A)100 mg/day
B)200 mg/day
C)300 mg/day
D)400 mg/day

Question 38

Which of the following medications requires the patient to be informed that he or she should avoid large amounts of tyramine-containing foods,alcoholic beverages,large quantities of caffeine-containing beverages,and over-the-counter cough and cold medications?

A)selegeline (Carbex,Eldypryl)
B)levodopa/carbadopa
C)galantamine (Razadyne)
D)tacrine (Cognex)

Question 39

Which of the following drugs is a selective MAO-B inhibitor?

A)entacapone (Comtan)
B)selegiline (Eldypryl,Carbex)
C)pramipexole (Mirapex)
D)benztropine (Cogentin)

Question 40

Which of the following drugs can increase blood levels of hypnotics?

A)cimetadine (Tagamet)
B)rifampin (Rifadin)
C)phenytoin (Dilantin)
D)ketoconazole (Nizoril)