Deck 18: Antineoplastic Agents

Question 1

Cancer is routinely treated with

A) surgery
B) medications
C) radiation
D) all of the above
E) a and c

Answer 1

all of the above

Question 2

Cytotoxic medications may be given

A) IM
B) IV
C) orally
D) SC
E) all of the above

Answer 2

all of the above

Question 3

Side effects of antineoplastics include

A) alopecia
B) nausea and vomiting
C) stomatitis
D) anemia
E) all of the above

Answer 3

all of the above

Question 4

The dosage of chemotherapeutic agents takes into account the

A) age and gender of the patient
B) stage of the disease
C) prognosis of the disease
D) cost of the treatment versus the ability to benefit from therapy
E) all of the above

Question 5

Toxic effects of chemotherapeutic agents include

A) cardiotoxicity
B) hepatotoxicity
C) neurotoxicity
D) pulmonary toxicity
E) all except d

Question 6

Neoplastic diseases are caused by uncontrolled cell division.

Question 7

Antineoplastic or chemotherapeutic agents are used to counteract the development, growth, or spread of abnormal cells.

Question 8

Signs and symptoms of antineoplastic toxicity that should be reported to the physician include

A) rash
B) weight gain
C) unusual bleeding or bruising
D) all of the above
E) a and c

Question 9

Benign tumors are named by the site plus "oma," as in

A) lipoma
B) adenoma
C) sarcoma
D) all of the above
E) all except c

Question 10

In preparing cytotoxic medications, which of the following must be used?

A) personal protective equipment
B) special exhaust fans
C) aseptic technique
D) all of the above
E) a and c

Question 11

The patient may better tolerate chemotherapy and its side effects by

A) eating constipating foods
B) drinking liquids at times other than meals
C) eating a high-fiber diet
D) avoiding highly seasoned foods
E) all of the above

Question 12

All neoplasms are malignant.

Question 13

Characteristics of malignant tumors include

A) irregular shape
B) invasion of local tissue
C) possible invasion of lymph nodes
D) a and b
E) all of the above

Question 14

A mutated cell has an increased power to divide and enlarge to the size of a tumor.

Question 15

Nausea of chemotherapy may be reduced by eating

A) sweets
B) cold food or food at room temperature
C) small meals several times a day
D) all of the above
E) all except a

Question 16

The original site of a neoplasm is its primary site.

Question 17

Characteristics of benign tumors are that they

A) remain localized
B) are smooth and freely movable
C) are encapsulated
D) a and c
E) all of the above

Question 18

Tumors may be classified as either solid or fluid.

Question 19

Drugs to treat cancer are

A) hallucinogenic
B) carcinogenic
C) teratogenic
D) mutagenic
E) b, c, and d

Question 20

Common side effects of antineoplastic agents are

A) stomatitis
B) alopecia
C) suppression of blood elements
D) all of the above
E) a and b

Question 21

All patients are candidates for chemotherapy.

Question 22

If more than one chemotherapeutic agent is used, the action is in the same stage of the cell cycle so that the medication will kill the malignant cells.

Question 23

Tumors are classified by their stages of invasion from Stage A to Stage D.

Question 24

Drugs for cancer are slow to reach the market because the FDA wants to be sure these drugs cannot destroy normal cells with the abnormal cells.

Question 25

Sedatives and antiemetics may be given prior to chemotherapy to minimize nausea and vomiting.

Question 26

Chemotherapeutic agents are always given as one medication so that the possible toxicities may be evaluated.

Question 27

Healthy cells are destroyed with antineoplastics, but they will repair and regenerate to normal numbers faster than cancer cells.

Question 28

Tissue death may occur at the site of antineoplastic administration, so the patient should be taught the signs of infection and inflammation.

Question 29

Cytotoxic agents may have to be discontinued because of their adverse effects.

Question 30

In prescribing an antineoplastic, the gains to be obtained must be weighed against any severe side effects.

Question 31

Cytotoxics are toxic to malignant and normal tissue cells.

Question 32

Tumors may be invasive and move to nearby areas or may metastasize and move to distant tissue.

Question 33

Good oral hygiene is essential with chemotherapy, as lesions of the mouth and tongue are common.

Question 34

All types of cancers may be treated with chemotherapy.

Question 35

Chemotherapy is most effective on small tumors because they have a more efficient blood supply.

Question 36

As a tumor increases in size, normal body cells receive more nutrition than necessary, allowing the tumor to increase in size.

Question 37

Confusion, slurred speech, and convulsions are signs of toxicity to chemotherapy.

Question 38

Antineoplastics are used only for malignant growths.

Question 39

Chemotherapy is used to eradicate the possibility of micrometastasis following surgery and radiation.

Question 40

Chemotherapy is always performed following surgery and before radiation.

Question 41

Antimetabolites are effective on DNA synthesis.

Question 42

Palliation is a reason for using chemotherapy.

Question 43

Interferon is an immunosuppressant made by recombinant DNA.

Question 44

Cancers associated with AIDS do not respond to the same medications used for other types of malignancies.

Question 45

Cell-phase-specific drugs are effective only at a specific phase of the cell cycle.

Question 46

Alopecia occurs with all chemotherapy.

Question 47

Cytotoxic medications given SC or IM may cause tissue damage.

Question 48

BSA is the best way to determine the dosage of chemotherapeutic agents.

Question 49

Antitumor antibiotics have the same chemical basis as antibiotics used to treat infections.

Question 50

Plant alkaloids are effective in the metaphase of the cell cycle.

Question 51

Antibiotics used as chemotherapeutic agents are the same as those used for infectious diseases.

Question 52

Sex hormones may be used palliatively for tumors of the reproductive tract.

Question 53

Cost of medications used as chemotherapeutics is not a consideration when choosing the therapeutic medication.

Question 54

Exposure to radioisotopes may lead to radiation exposure to anyone around the isotopes.

Question 55

An obvious change in a mole or wart is a reason for seeking medical attention for the lesion.

Question 56

Persons of childbearing age should not reconstitute or administer chemotherapeutic agents.

Question 57

Antineoplastics may be administered by any health care professional.

Question 58

Fever, sore throats, blood dyscrasias, and infections are common with chemotherapy.

Question 59

Headaches with early morning vomiting may be a symptom of cancer.

Question 60

Some immunosuppressants may even render cancer cells nonmalignant.

Question 61

Malignant cells may enter body cavities by diffusion, thus making it hard to treat these cells.

Question 62

Match the following terms with their descriptions below.
Agent that causes abnormal development of a fetus

A)carcinogenic
B)mutagenic
C)teratogenic
D)benign
E)malignant

Question 63

Match the following terms with their descriptions below.
Radioactive form of an element used to treat neoplasms

A)antimetabolite
B)cytotoxic agent
C)plant alkaloid
D)alkylating agent
E)radioisotope

Question 64

Match the following terms with their descriptions below.
Compounds that cause cell destruction

A)antimetabolite
B)cytotoxic agent
C)plant alkaloid
D)alkylating agent
E)radioisotope

Question 65

Cancer is a mass of cells with no useful function.

Question 66

Cancer is a single disease.

Question 67

Antineoplastics are effective for leukemias because blood elements are suppressed.

Question 68

The more rapidly cancer cells proliferate, the less likely antineoplastic agents will be effective.

Question 69

Normal body cells are not affected by malignant cells.

Question 70

Match the following terms with their descriptions below.
Substance that has the ability to interfere with cell metabolism and growth

A)antimetabolite
B)cytotoxic agent
C)plant alkaloid
D)alkylating agent
E)radioisotope

Question 71

Match the following terms with their descriptions below.
Group of organic alkaline substances obtained from plants for medicinal purposes

A)antimetabolite
B)cytotoxic agent
C)plant alkaloid
D)alkylating agent
E)radioisotope

Question 72

When antineoplastics are administered for palliative effects, usually only one agent is used as further treatment may be needed in the future using other agents.

Question 73

Anaplastic cells occur with grade 1 tumors.

Question 74

Lethargy may be a sign of cancer, especially if it persists.

Question 75

Research into effective treatment of cancer is based on the high mortality and morbidity rates of the disease.

Question 76

When a malignant cell moves to a new body organ, the new site is considered a primary site.

Question 77

Fever of unknown cause in children is not indication for a possible malignancy.

Question 78

Cell morphology for a diagnosis and for use of antineoplastics in metastasis is easier when the metastatic tumor mimics the primary tumor.

Question 79

Normal body cells decrease in numbers as malignant cells increase in number.

Question 80

Match the following terms with their descriptions below.
Class of medications that are used to treat malignancies effectively by interfering with DNA metabolism

A)antimetabolite
B)cytotoxic agent
C)plant alkaloid
D)alkylating agent
E)radioisotope