Question 1

What is the pathological mechanism that leads to neurological dysfunction in multiple sclerosis?&#10;A)Proliferation of oligodendrocytes&#10;B)Inflammatory processes&#10;C)Axonal disruption&#10;D)Interruption of cerebral blood flow

Accepted Answer

C

Question 2

Individuals with multiple sclerosis who are MORE likely to benefit from a maintenance therapy program fall within which range of scores on the Expanded Disability Status Scale?&#10;A)0 to 2.5&#10;B)3 to 5&#10;C)5.5 to 7&#10;D)7.5 to 9.5

Accepted Answer

D

Question 3

Which of the following BEST describes the response of a patient with multiple sclerosis who experiences a worsening of spasticity and blurring of vision after 60 minutes of vigorous exercise that subsides within 12 hours?

A)Exacerbation
B)Pseudoexacerbation
C)Appropriate response to exercise
D)Myocardial infarction

B

Accepted Answer

This is likely a pseudoexacerbation, which is a temporary worsening of symptoms due to external factors such as heat, stress, or vigorous exercise. The fact that the symptoms subside within 12 hours suggests that it is not a true exacerbation. The other choices (A, C, D) are not relevant to the symptoms described.

Question 4

Which of the following statements regarding pain in multiple sclerosis is true?&#10;A)It is usually musculoskeletal in nature.&#10;B)It is always acute,never chronic.&#10;C)It frequently presents in the face.&#10;D)It is usually dull and throbbing in nature.

Accepted Answer

Pain in multiple sclerosis can present in various forms and locations, but it is often seen as a facial pain. It can also manifest as chronic or acute pain, and in different forms such as sharp, burning or aching sensations. Therefore, options A, B and D are incorrect.

Question 5

Which one of the following symptoms is atypical for patients with multiple sclerosis?&#10;A)Neurogenic fatigue&#10;B)Flaccid paralysis&#10;C)Visual loss&#10;D)Sensory paresthesia

Accepted Answer

Flaccid paralysis is not a common symptom of multiple sclerosis. This type of paralysis is caused by damage to the lower motor neurons, which is not typically seen in MS. Common symptoms of MS include neurogenic fatigue, visual loss, and sensory paresthesia.

Question 6

Which medication is MOST appropriate for the medical management of acute relapses in multiple sclerosis?&#10;A)Interferon beta-1a&#10;B)Methylprednisolone&#10;C)Mitoxantrone hydrochloride&#10;D)Baclofen

Accepted Answer

Methylprednisolone is the treatment of choice for managing acute relapses in multiple sclerosis as it reduces inflammation around the affected nerves, thus providing symptomatic relief. Interferon beta-1a and mitoxantrone hydrochloride are disease-modifying therapies and are not used for managing acute relapses. Baclofen is a muscle relaxant and is used for managing spasticity in multiple sclerosis, but not for acute relapses.

Deck 16: Multiple Sclerosis