Deck 22: Lymphatic System and Immunity

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سؤال
What is the purpose of lacteals?

A)Drain blood from the spleen.
B)Absorb fluid from capillary beds.
C)Absorb lipids from the digestive tract.
D)Absorb solutes from interstitial spaces.
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سؤال
Which of the following is NOT a function of the lymphatic system?

A)Defending from infection caused by microorganisms and other foreign substances.
B)Aiding in erythropoiesis of red blood cells.
C)Maintaining fluid balance by returning excess interstitial fluid to the blood.
D)Absorbing and transporting lipids from the digestive tract.
سؤال
How do lymphatic capillaries differ form blood capillaries?

A)Lymphatic capillaries do not have a basement membrane.
B)Simple squamous epithelial cells of lymphatics overlap with loose attachments.
C)Lymphatic capillaries are more permeable than blood capillaries.
D)Lymphatic capillary epithelium act as one-way valves preventing movement of fluid back into interstitial spaces.
E)All of the choices are ways lymphatic capillaries differ from blood capillaries.
سؤال
The right lymphatic duct drains lymph from the

A)abdomen.
B)upper part of the body.
C)right arm,right chest,and right side of head.
D)right side of the body.
E)left arm,left chest,and left side of head.
سؤال
What structural feature of lymphatic vessels is responsible to forward movement of lymph?

A)over-lapping endothelial cells
B)valves
C)no basement membrane
D)thin walls
سؤال
Structurally,lymph vessels are most similar to

A)veins.
B)arteries.
C)arterioles.
D)capillaries.
E)venules.
سؤال
Lacteals are

A)a type of lymphocyte.
B)a nonspecific defense.
C)lymphatic vessels in the lining of the small intestine.
D)the sinuses inside a lymph node.
E)germinal centers.
سؤال
A woman has her right breast and right axillary lymph nodes removed.Which of the following might occur?

A)Cisterna chyli flow increases.
B)The thoracic duct would be severed.
C)Right lymphatic duct drainage decreases causing edema in the right arm.
D)Lymph drainage would be affected in her left arm.
E)Lymph drainage would be affected in both legs.
سؤال
The lymphatic system plays a role in maintaining fluid balance within the body by

A)adding lymph to GI tract secretions.
B)returning interstitial fluid to the plasma.
C)transporting lymph from tissues to the liver.
D)carrying excess fluid to the kidneys to be excreted.
E)actively absorbing fluid from the blood.
سؤال
Which of the following organs does NOT contain lymphatic tissue?

A)liver
B)spleen
C)lingual tonsils
D)thymus
E)pharyngeal tonsils.
سؤال
Lymph nodules are

A)small,bean-shaped structures.
B)the site of erythrocyte production.
C)located in the loose connective tissue of the digestive system.
D)composed of an outer cortex and inner medulla.
E)connected together in a series.
سؤال
The lymphatic system is involved in

A)lipid absorption from the digestive tract.
B)transporting lymph from the intestines to the liver.
C)maintenance of pH in the tissues.
D)production of erythrocytes.
E)protein metabolism.
سؤال
The thoracic duct drains lymph into the

A)left subclavian vein.
B)right subclavian vein.
C)right internal jugular vein.
D)left brachiocephalic vein.
E)left subclavian artery.
سؤال
Lymph movement is assisted by

A)contraction of skeletal muscle.
B)contraction of smooth muscle in lymph vessel.
C)pressure changes in the thorax during respiration.
D)compression of lymphatic vessels.
E)All of these choices are correct.
سؤال
The lymphatic system differs from the cardiovascular system in that

A)the lymphatic system only carries fluid away from tissues.
B)the lymphatic vessels have their own "pump" to assist flow.
C)lymph capillaries do not contain any fluid.
D)lymph capillaries allow free movement of fluid in and out of the capillaries.
E)lymph circulates fluids and cardiovascular does not.
سؤال
Nonencapsulated lymphatic tissue called MALT includes all of the following except:

A)tonsils.
B)Peyer patches.
C)lymph nodes.
D)diffuse lymphatic tissue.
سؤال
Peyer patches are lymphatic nodules found in the

A)lymph nodes.
B)spleen and tonsils.
C)appendix and tonsils.
D)small intestine and appendix.
سؤال
Lymphatic tissue contains an interlaced network of reticular fibers that functions to

A)produce lymphocytes.
B)produce capsules around lymph nodes.
C)attack microorganisms.
D)line the walls of lymphatic vessels.
E)trap microorganisms.
سؤال
Lymph capillaries are found in the

A)epidermis.
B)cornea.
C)bone marrow.
D)central nervous system.
E)dermis.
سؤال
Lymph containing a high lipid content is called

A)chyle.
B)chyme.
C)lacteal.
D)interstitial fluid.
سؤال
When innate immunity is activated,

A)each exposure is very specific.
B)previous exposures are remembered.
C)each exposure produces the same response.
D)each exposure increases the strength of the immune response.
E)the second exposure does not produce a response.
سؤال
Complement proteins

A)can form holes in the plasma membrane of target cells.
B)are on the surface of macrophages.
C)are hormones found in the blood.
D)may cause the release of interferon.
E)do not attract neutrophils,monocytes,macrophages,or eosinophils.
سؤال
What is the function of thymosin?

A)destroys damaged red blood cells
B)destroys damaged white blood cells
C)activates lymphocytes in lymph nodes
D)maturation of T-cells
سؤال
Bacteria and debris are actively removed from the lymph by _____ in the sinuses of lymph nodes.

A)trabecular cells
B)germinal cells
C)macrophages.
D)lymphocytes
E)plasma cells
سؤال
Which of the following is NOT a characteristic of adaptive immunity?

A)It has memory.
B)You are born with it.
C)It has specificity.
D)Acquired throughout your lifetime.
سؤال
The spleen

A)filters damaged red blood cells from the blood.
B)changes undifferentiated lymphocytes into competent lymphocytes.
C)is necessary for life.It can't be removed without causing death.
D)produces several different hormones with unknown function.
E)has additional digestive functions.
سؤال
Which of the following characteristics is/are most consistent with adaptive immunity?

A)constant response to each exposure
B)specificity
C)memory
D)increased response to second and subsequent exposures
E)specificity,memory and increased response to second and subsequent exposures
سؤال
Which of the following is true of adaptive immunity?

A)It is present at birth.
B)Previous encounters with the foreign substance does not change the response.
C)The second response is faster and stronger than the first response.
D)Responses are general,not specific.
سؤال
Which of the following statements accurately describes the thymus gland?

A)The thymus gland lacks a capsule.
B)The thymus gland contains many reticular fibers.
C)The thymus gland decreases in size after age 60.
D)Lymphocytes are found only in the medulla of the thymus gland.
E)The thymus increases in size with aging.
سؤال
Adenoids are enlarged

A)lingual tonsils.
B)pharyngeal tonsils.
C)palatine tonsils.
D)cervical lymph nodes.
E)axillary lymph nodes.
سؤال
The only structures that filter lymph is/are the

A)tonsils.
B)spleen.
C)lymph nodes.
D)thymus.
سؤال
Which of the following would be classified as an innate physical barrier?

A)activation of complement
B)phagocytosis of invading organisms
C)washing action of tears and saliva
D)inflammation
E)release of histamine
سؤال
The palatine tonsils

A)interfere with breathing when enlarged.
B)are located at the junction of the oral cavity and pharynx.
C)are located superior to the palate.
D)are really lymph nodes in disguise.
E)are located in the nasopharynx.
سؤال
Tonsils

A)increase in size in adults.
B)are located in both the oral and abdominal cavities.
C)provide protection against bacteria entering the oral and nasal cavities.
D)contain red pulp and white pulp.
E)are not functional in children.
سؤال
The white pulp of the spleen

A)contains lymphocytes that can stimulate an immune response.
B)filters lymph as it flows through the spleen.
C)destroys defective red blood cells.
D)stimulates immune responses,filter lymph,and destroys defective red blood cells.
سؤال
Germinal centers are the sites of

A)increased blood flow to the lymph nodes.
B)fluid production.
C)increased flow of lymph from infected tissues.
D)entrance of lymph into lymph nodes.
E)proliferation of lymphocytes in the lymph nodes.
سؤال
Which of the following statements concerning the spleen is true?

A)Splenic arteries enter the organ at the periarterial sheath.
B)The spleen can act as a blood reservoir.
C)The white pulp is associated with the venous supply.
D)The red pulp has trabeculae.
E)Humans can not survive without a spleen.
سؤال
Bean-shaped lymphatic organs found along lymphatic vessels are called

A)lymph nodes.
B)medullary cords.
C)cisterna chyli.
D)trabeculae.
E)lymph nodules.
سؤال
Lymph exits a lymph node via the

A)efferent lymphatic vessels.
B)afferent lymphatic vessels.
C)cortical sinuses.
D)trabeculae.
E)lymphatic duct.
سؤال
Lymph nodes are surrounded by a dense connective tissue called

A)cortex.
B)capsule.
C)reticulum.
D)trabeculum.
E)basement membrane.
سؤال
The movement of leukocytes to the source of certain chemicals is called

A)chemotaxis.
B)opsonization.
C)chemoreception.
D)phagocytosis.
E)hemolysis.
سؤال
In a patient experiencing a parasitic worm infection,which of the following immune cells will greatly increase in number?

A)mast cells
B)eosinophils
C)monocytes
D)neutrophils
E)basophils
سؤال
Which of the following substances causes increased capillary permeability,chemotaxis,and vasodilation?

A)histamine
B)protaglandins
C)leukotrienes
D)complement
E)cytokines
سؤال
The inflammatory response

A)prevents the spread of an infection.
B)stimulates erythrocytes to leave the blood.
C)delays healing of damaged tissues.
D)depresses immunity.
E)is harmful and should be immediately reversed.
سؤال
A protein that helps to protect the body against viral infections is

A)complement.
B)interferon.
C)lysozyme.
D)histamine.
E)kinin.
سؤال
The two major types of phagocytic cells are

A)neutrophils and monocytes.
B)neutrophils and macrophages.
C)monocytes and macrophages.
D)lymphocytes and monocytes.
E)eosinophils and T cells.
سؤال
Which of the following is usually the first cell type to leave the blood and enter infected tissues?

A)eosinophil
B)lymphocyte
C)monocyte
D)natural killer cell
E)neutrophil
سؤال
The key signs of inflammation include all of the following EXCEPT

A)jaundice.
B)pain.
C)swelling.
D)redness.
E)heat.
سؤال
Which of the following statements concerning neutrophils and macrophages is false?

A)They both exhibit chemotaxis.
B)They both move by amoeboid motion.
C)Both are capable of phagocytosis.
D)Both release histamine when activated.
E)Both can squeeze between cells.
سؤال
A surface chemical that prevents microbial growth is

A)histamine.
B)leukotriene.
C)sebum.
D)kinin.
E)interferon.
سؤال
Which of the following is NOT a mechanism of complement action?

A)produces cytokines
B)opsonization
C)attracts other immune cells to the site of infection
D)forms a MAC that leads to cell lysis
سؤال
Lysozyme is

A)an enzyme found in body fluids that destroys certain bacteria.
B)a type of antibody that attracts a phagocyte.
C)a cytokine produced by T cells.
D)an antigen.
E)a bacteria.
سؤال
Interferon

A)directly attacks viruses.
B)protects cells that have been invaded by viruses.
C)increases vascular permeability.
D)is not produced by most cells.
E)is a protein that interferes with virus production and infection.
سؤال
Natural Killer (NK)cells

A)a type of macrophage.
B)are a type of plasma cell.
C)secrete enzymes that kill tumor or virus-infected cells.
D)are derived from B cells.
E)promote inflammation.
سؤال
During the inflammatory response,

A)vasoconstriction occurs.
B)chemical mediators are released.
C)vascular permeability is decreased.
D)neutrophil production is depressed.
E)blood flow is reduced.
سؤال
Macrophages

A)are derived from basophils.
B)reduce the inflammatory response.
C)are responsible for most phagocytic activity in the late stages of an infection.
D)produce cytokines that aid in the destruction of antigens.
E)are the first at the site of infection.
سؤال
Histamine and leukotrienes are released from

A)basophils and mast cells.
B)eosinophils and basophils.
C)neutrophils and lymphocytes.
D)macrophages and microphages.
E)phagocytes.
سؤال
The redness and heat seen in an inflamed area are the result of

A)vasoconstriction.
B)increased blood flow to the area.
C)phagocyte mobilization.
D)production of interferon.
E)a reddish substance released by erythrocytes.
سؤال
Interferon production is stimulated by

A)a viral infection.
B)the complement cascade.
C)antigen-presenting cells.
D)degranulation of basophils.
E)inflammation.
سؤال
Which of the following most accurately describes how foreign substances can activate complement?

A)Antibodies can bind to foreign antigens and activate complement through the classical pathway.
B)Foreign substances can bind to spontaneously activated C3 and stabilize it.
C)Foreign proteins bind to C1 and activate it.
D)Foreign proteins are phagocytized by macrophages and directly activate complement.
E)Antibodies can bind to foreign antigens and activate complement through the classical pathway and foreign substances can bind to spontaneously activated C3 and stabilize it.
سؤال
The effects of cell-mediated immunity are the result of activities of

A)B cells.
B)cytotoxic T cells.
C)macrophages.
D)dendritic cells.
E)helper T cells.
سؤال
Circulatory changes that occur in inflammation include

A)increased viscosity of the blood.
B)decreased vascular permeability.
C)increased vascular permeability.
D)decreased blood flow to the area.
E)vasoconstriction.
سؤال
What areas of an antigen are recognized by lymphocytes so that they can respond?

A)major histocompatibility complexes
B)antigenic determinants
C)T-cell receptors
D)epitopes
E)Both antigenic determinants and epitopes are correct.
سؤال
Adaptive immunity is stimulated by

A)antigens.
B)histamines.
C)antibodies.
D)complement.
E)plasma proteins.
سؤال
In systemic inflammation,pyrogens

A)decrease phagocytosis.
B)decrease vasodilation.
C)increase neutrophil production.
D)stimulate fever production.
E)are chemotaxic factors.
سؤال
Which of the following is NOT a secondary lymphatic organ?

A)spleen
B)lymph node
C)lymphatic nodule
D)thymus gland
سؤال
The process of eliminating those lymphocytes that react or respond against self-antigens is called

A)phagocytosis.
B)inflammation.
C)negative selection.
D)activation of complement.
E)natural selection.
سؤال
______ determines which B-cell is cloned in an antibody-mediated response.

A)The antibody
B)The antigen
C)A macrophage
D)Complement
E)A neutrophil
سؤال
Which of the following is a subpopulation of T cells?

A)cytotoxic
B)antigenic
C)cytokinetic
D)basophilic
E)antitoxic
سؤال
Transplanted tissues and organs that contain _________ _________ are rejected by the body.

A)self-antigens
B)foreign antigens
C)foreign antibodies
D)self-antibodies
E)plasma proteins
سؤال
A small molecule that can cause an allergic reaction is a/an

A)T cell.
B)B cell.
C)antibody.
D)hapten.
سؤال
Different T-cell receptors can respond to different antigens because of different

A)variable regions in the structure of the receptors.
B)epitopes in the receptor's structure.
C)selection processes.
D)complement binding sites in the receptors.
E)antigenic determinants.
سؤال
Positive selection of lymphocytes refers to the

A)processing of an antigen by a macrophage.
B)proliferation of natural killer cells.
C)production of antigen-specific antibodies.
D)survival of pre-B and pre-T cells that are capable of an immune response.
E)replication of memory cells.
سؤال
The MHC (major histocompatibility complex)class molecules

A)are only found on B cells.
B)are found in the nucleus of cells.
C)allow the immune system to respond to antigens inside cells.
D)are lipoproteins on cell surfaces.
E)do not attach to plasma membranes.
سؤال
MHC class II molecules are found on

A)neutrophils,monocytes,and macrophages.
B)dendritic cells,B cells,and helper T cells.
C)monocytes,helper T cells,and neutrophils.
D)B cells,macrophages,and dendritic cells.
E)B cells,C cells and D cells.
سؤال
Lymphocyte activation can occur in several ways.However,in all cases

A)lymphocytes must recognize an antigen.
B)helper T cells are activated first and they then stimulate other cells.
C)antigen-presenting cells process the antigen and present it to the lymphocytes.
D)cytokines released by the antigen stimulate the lymphocyte response.
E)antigens must be able to recognize the lymphocytes.
سؤال
The thymus is where ____ mature and become functional immune cells.

A)pre-T cells
B)pre-B cells
C)macrophages
D)null cells
E)C cells.
سؤال
____ are part of cell-mediated immunity while ____ are part of antibody-mediated immunity.

A)B cells,NK cells
B)Antibodies,antigens
C)T cells,B cells
D)Macrophages,antibodies
E)Neutrophils,monocytes
سؤال
Primary lymphatic organs include the

A)tonsils and spleen.
B)thymus and lymph nodes.
C)red bone marrow and thymus.
D)red bone marrow and lymph nodes.
سؤال
The MHC class I antigen complex displays a foreign antigen on the cell surface.This prompts the immune system to destroy

A)B cell clones.
B)extracellular antigens.
C)the displaying cell.
D)mature red blood cells.
E)the virus inside the cell,but not the cell.
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ملء الشاشة (f)
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Deck 22: Lymphatic System and Immunity
1
What is the purpose of lacteals?

A)Drain blood from the spleen.
B)Absorb fluid from capillary beds.
C)Absorb lipids from the digestive tract.
D)Absorb solutes from interstitial spaces.
C
2
Which of the following is NOT a function of the lymphatic system?

A)Defending from infection caused by microorganisms and other foreign substances.
B)Aiding in erythropoiesis of red blood cells.
C)Maintaining fluid balance by returning excess interstitial fluid to the blood.
D)Absorbing and transporting lipids from the digestive tract.
B
3
How do lymphatic capillaries differ form blood capillaries?

A)Lymphatic capillaries do not have a basement membrane.
B)Simple squamous epithelial cells of lymphatics overlap with loose attachments.
C)Lymphatic capillaries are more permeable than blood capillaries.
D)Lymphatic capillary epithelium act as one-way valves preventing movement of fluid back into interstitial spaces.
E)All of the choices are ways lymphatic capillaries differ from blood capillaries.
E
4
The right lymphatic duct drains lymph from the

A)abdomen.
B)upper part of the body.
C)right arm,right chest,and right side of head.
D)right side of the body.
E)left arm,left chest,and left side of head.
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5
What structural feature of lymphatic vessels is responsible to forward movement of lymph?

A)over-lapping endothelial cells
B)valves
C)no basement membrane
D)thin walls
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6
Structurally,lymph vessels are most similar to

A)veins.
B)arteries.
C)arterioles.
D)capillaries.
E)venules.
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7
Lacteals are

A)a type of lymphocyte.
B)a nonspecific defense.
C)lymphatic vessels in the lining of the small intestine.
D)the sinuses inside a lymph node.
E)germinal centers.
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8
A woman has her right breast and right axillary lymph nodes removed.Which of the following might occur?

A)Cisterna chyli flow increases.
B)The thoracic duct would be severed.
C)Right lymphatic duct drainage decreases causing edema in the right arm.
D)Lymph drainage would be affected in her left arm.
E)Lymph drainage would be affected in both legs.
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9
The lymphatic system plays a role in maintaining fluid balance within the body by

A)adding lymph to GI tract secretions.
B)returning interstitial fluid to the plasma.
C)transporting lymph from tissues to the liver.
D)carrying excess fluid to the kidneys to be excreted.
E)actively absorbing fluid from the blood.
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10
Which of the following organs does NOT contain lymphatic tissue?

A)liver
B)spleen
C)lingual tonsils
D)thymus
E)pharyngeal tonsils.
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11
Lymph nodules are

A)small,bean-shaped structures.
B)the site of erythrocyte production.
C)located in the loose connective tissue of the digestive system.
D)composed of an outer cortex and inner medulla.
E)connected together in a series.
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12
The lymphatic system is involved in

A)lipid absorption from the digestive tract.
B)transporting lymph from the intestines to the liver.
C)maintenance of pH in the tissues.
D)production of erythrocytes.
E)protein metabolism.
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13
The thoracic duct drains lymph into the

A)left subclavian vein.
B)right subclavian vein.
C)right internal jugular vein.
D)left brachiocephalic vein.
E)left subclavian artery.
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14
Lymph movement is assisted by

A)contraction of skeletal muscle.
B)contraction of smooth muscle in lymph vessel.
C)pressure changes in the thorax during respiration.
D)compression of lymphatic vessels.
E)All of these choices are correct.
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15
The lymphatic system differs from the cardiovascular system in that

A)the lymphatic system only carries fluid away from tissues.
B)the lymphatic vessels have their own "pump" to assist flow.
C)lymph capillaries do not contain any fluid.
D)lymph capillaries allow free movement of fluid in and out of the capillaries.
E)lymph circulates fluids and cardiovascular does not.
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16
Nonencapsulated lymphatic tissue called MALT includes all of the following except:

A)tonsils.
B)Peyer patches.
C)lymph nodes.
D)diffuse lymphatic tissue.
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17
Peyer patches are lymphatic nodules found in the

A)lymph nodes.
B)spleen and tonsils.
C)appendix and tonsils.
D)small intestine and appendix.
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18
Lymphatic tissue contains an interlaced network of reticular fibers that functions to

A)produce lymphocytes.
B)produce capsules around lymph nodes.
C)attack microorganisms.
D)line the walls of lymphatic vessels.
E)trap microorganisms.
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19
Lymph capillaries are found in the

A)epidermis.
B)cornea.
C)bone marrow.
D)central nervous system.
E)dermis.
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20
Lymph containing a high lipid content is called

A)chyle.
B)chyme.
C)lacteal.
D)interstitial fluid.
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21
When innate immunity is activated,

A)each exposure is very specific.
B)previous exposures are remembered.
C)each exposure produces the same response.
D)each exposure increases the strength of the immune response.
E)the second exposure does not produce a response.
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22
Complement proteins

A)can form holes in the plasma membrane of target cells.
B)are on the surface of macrophages.
C)are hormones found in the blood.
D)may cause the release of interferon.
E)do not attract neutrophils,monocytes,macrophages,or eosinophils.
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23
What is the function of thymosin?

A)destroys damaged red blood cells
B)destroys damaged white blood cells
C)activates lymphocytes in lymph nodes
D)maturation of T-cells
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24
Bacteria and debris are actively removed from the lymph by _____ in the sinuses of lymph nodes.

A)trabecular cells
B)germinal cells
C)macrophages.
D)lymphocytes
E)plasma cells
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25
Which of the following is NOT a characteristic of adaptive immunity?

A)It has memory.
B)You are born with it.
C)It has specificity.
D)Acquired throughout your lifetime.
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26
The spleen

A)filters damaged red blood cells from the blood.
B)changes undifferentiated lymphocytes into competent lymphocytes.
C)is necessary for life.It can't be removed without causing death.
D)produces several different hormones with unknown function.
E)has additional digestive functions.
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27
Which of the following characteristics is/are most consistent with adaptive immunity?

A)constant response to each exposure
B)specificity
C)memory
D)increased response to second and subsequent exposures
E)specificity,memory and increased response to second and subsequent exposures
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28
Which of the following is true of adaptive immunity?

A)It is present at birth.
B)Previous encounters with the foreign substance does not change the response.
C)The second response is faster and stronger than the first response.
D)Responses are general,not specific.
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29
Which of the following statements accurately describes the thymus gland?

A)The thymus gland lacks a capsule.
B)The thymus gland contains many reticular fibers.
C)The thymus gland decreases in size after age 60.
D)Lymphocytes are found only in the medulla of the thymus gland.
E)The thymus increases in size with aging.
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30
Adenoids are enlarged

A)lingual tonsils.
B)pharyngeal tonsils.
C)palatine tonsils.
D)cervical lymph nodes.
E)axillary lymph nodes.
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31
The only structures that filter lymph is/are the

A)tonsils.
B)spleen.
C)lymph nodes.
D)thymus.
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32
Which of the following would be classified as an innate physical barrier?

A)activation of complement
B)phagocytosis of invading organisms
C)washing action of tears and saliva
D)inflammation
E)release of histamine
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33
The palatine tonsils

A)interfere with breathing when enlarged.
B)are located at the junction of the oral cavity and pharynx.
C)are located superior to the palate.
D)are really lymph nodes in disguise.
E)are located in the nasopharynx.
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34
Tonsils

A)increase in size in adults.
B)are located in both the oral and abdominal cavities.
C)provide protection against bacteria entering the oral and nasal cavities.
D)contain red pulp and white pulp.
E)are not functional in children.
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35
The white pulp of the spleen

A)contains lymphocytes that can stimulate an immune response.
B)filters lymph as it flows through the spleen.
C)destroys defective red blood cells.
D)stimulates immune responses,filter lymph,and destroys defective red blood cells.
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36
Germinal centers are the sites of

A)increased blood flow to the lymph nodes.
B)fluid production.
C)increased flow of lymph from infected tissues.
D)entrance of lymph into lymph nodes.
E)proliferation of lymphocytes in the lymph nodes.
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37
Which of the following statements concerning the spleen is true?

A)Splenic arteries enter the organ at the periarterial sheath.
B)The spleen can act as a blood reservoir.
C)The white pulp is associated with the venous supply.
D)The red pulp has trabeculae.
E)Humans can not survive without a spleen.
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38
Bean-shaped lymphatic organs found along lymphatic vessels are called

A)lymph nodes.
B)medullary cords.
C)cisterna chyli.
D)trabeculae.
E)lymph nodules.
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39
Lymph exits a lymph node via the

A)efferent lymphatic vessels.
B)afferent lymphatic vessels.
C)cortical sinuses.
D)trabeculae.
E)lymphatic duct.
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40
Lymph nodes are surrounded by a dense connective tissue called

A)cortex.
B)capsule.
C)reticulum.
D)trabeculum.
E)basement membrane.
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41
The movement of leukocytes to the source of certain chemicals is called

A)chemotaxis.
B)opsonization.
C)chemoreception.
D)phagocytosis.
E)hemolysis.
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42
In a patient experiencing a parasitic worm infection,which of the following immune cells will greatly increase in number?

A)mast cells
B)eosinophils
C)monocytes
D)neutrophils
E)basophils
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43
Which of the following substances causes increased capillary permeability,chemotaxis,and vasodilation?

A)histamine
B)protaglandins
C)leukotrienes
D)complement
E)cytokines
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44
The inflammatory response

A)prevents the spread of an infection.
B)stimulates erythrocytes to leave the blood.
C)delays healing of damaged tissues.
D)depresses immunity.
E)is harmful and should be immediately reversed.
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45
A protein that helps to protect the body against viral infections is

A)complement.
B)interferon.
C)lysozyme.
D)histamine.
E)kinin.
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46
The two major types of phagocytic cells are

A)neutrophils and monocytes.
B)neutrophils and macrophages.
C)monocytes and macrophages.
D)lymphocytes and monocytes.
E)eosinophils and T cells.
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47
Which of the following is usually the first cell type to leave the blood and enter infected tissues?

A)eosinophil
B)lymphocyte
C)monocyte
D)natural killer cell
E)neutrophil
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48
The key signs of inflammation include all of the following EXCEPT

A)jaundice.
B)pain.
C)swelling.
D)redness.
E)heat.
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49
Which of the following statements concerning neutrophils and macrophages is false?

A)They both exhibit chemotaxis.
B)They both move by amoeboid motion.
C)Both are capable of phagocytosis.
D)Both release histamine when activated.
E)Both can squeeze between cells.
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50
A surface chemical that prevents microbial growth is

A)histamine.
B)leukotriene.
C)sebum.
D)kinin.
E)interferon.
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51
Which of the following is NOT a mechanism of complement action?

A)produces cytokines
B)opsonization
C)attracts other immune cells to the site of infection
D)forms a MAC that leads to cell lysis
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52
Lysozyme is

A)an enzyme found in body fluids that destroys certain bacteria.
B)a type of antibody that attracts a phagocyte.
C)a cytokine produced by T cells.
D)an antigen.
E)a bacteria.
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53
Interferon

A)directly attacks viruses.
B)protects cells that have been invaded by viruses.
C)increases vascular permeability.
D)is not produced by most cells.
E)is a protein that interferes with virus production and infection.
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54
Natural Killer (NK)cells

A)a type of macrophage.
B)are a type of plasma cell.
C)secrete enzymes that kill tumor or virus-infected cells.
D)are derived from B cells.
E)promote inflammation.
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55
During the inflammatory response,

A)vasoconstriction occurs.
B)chemical mediators are released.
C)vascular permeability is decreased.
D)neutrophil production is depressed.
E)blood flow is reduced.
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56
Macrophages

A)are derived from basophils.
B)reduce the inflammatory response.
C)are responsible for most phagocytic activity in the late stages of an infection.
D)produce cytokines that aid in the destruction of antigens.
E)are the first at the site of infection.
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57
Histamine and leukotrienes are released from

A)basophils and mast cells.
B)eosinophils and basophils.
C)neutrophils and lymphocytes.
D)macrophages and microphages.
E)phagocytes.
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58
The redness and heat seen in an inflamed area are the result of

A)vasoconstriction.
B)increased blood flow to the area.
C)phagocyte mobilization.
D)production of interferon.
E)a reddish substance released by erythrocytes.
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59
Interferon production is stimulated by

A)a viral infection.
B)the complement cascade.
C)antigen-presenting cells.
D)degranulation of basophils.
E)inflammation.
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60
Which of the following most accurately describes how foreign substances can activate complement?

A)Antibodies can bind to foreign antigens and activate complement through the classical pathway.
B)Foreign substances can bind to spontaneously activated C3 and stabilize it.
C)Foreign proteins bind to C1 and activate it.
D)Foreign proteins are phagocytized by macrophages and directly activate complement.
E)Antibodies can bind to foreign antigens and activate complement through the classical pathway and foreign substances can bind to spontaneously activated C3 and stabilize it.
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61
The effects of cell-mediated immunity are the result of activities of

A)B cells.
B)cytotoxic T cells.
C)macrophages.
D)dendritic cells.
E)helper T cells.
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62
Circulatory changes that occur in inflammation include

A)increased viscosity of the blood.
B)decreased vascular permeability.
C)increased vascular permeability.
D)decreased blood flow to the area.
E)vasoconstriction.
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63
What areas of an antigen are recognized by lymphocytes so that they can respond?

A)major histocompatibility complexes
B)antigenic determinants
C)T-cell receptors
D)epitopes
E)Both antigenic determinants and epitopes are correct.
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64
Adaptive immunity is stimulated by

A)antigens.
B)histamines.
C)antibodies.
D)complement.
E)plasma proteins.
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65
In systemic inflammation,pyrogens

A)decrease phagocytosis.
B)decrease vasodilation.
C)increase neutrophil production.
D)stimulate fever production.
E)are chemotaxic factors.
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66
Which of the following is NOT a secondary lymphatic organ?

A)spleen
B)lymph node
C)lymphatic nodule
D)thymus gland
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67
The process of eliminating those lymphocytes that react or respond against self-antigens is called

A)phagocytosis.
B)inflammation.
C)negative selection.
D)activation of complement.
E)natural selection.
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68
______ determines which B-cell is cloned in an antibody-mediated response.

A)The antibody
B)The antigen
C)A macrophage
D)Complement
E)A neutrophil
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69
Which of the following is a subpopulation of T cells?

A)cytotoxic
B)antigenic
C)cytokinetic
D)basophilic
E)antitoxic
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70
Transplanted tissues and organs that contain _________ _________ are rejected by the body.

A)self-antigens
B)foreign antigens
C)foreign antibodies
D)self-antibodies
E)plasma proteins
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71
A small molecule that can cause an allergic reaction is a/an

A)T cell.
B)B cell.
C)antibody.
D)hapten.
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72
Different T-cell receptors can respond to different antigens because of different

A)variable regions in the structure of the receptors.
B)epitopes in the receptor's structure.
C)selection processes.
D)complement binding sites in the receptors.
E)antigenic determinants.
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73
Positive selection of lymphocytes refers to the

A)processing of an antigen by a macrophage.
B)proliferation of natural killer cells.
C)production of antigen-specific antibodies.
D)survival of pre-B and pre-T cells that are capable of an immune response.
E)replication of memory cells.
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74
The MHC (major histocompatibility complex)class molecules

A)are only found on B cells.
B)are found in the nucleus of cells.
C)allow the immune system to respond to antigens inside cells.
D)are lipoproteins on cell surfaces.
E)do not attach to plasma membranes.
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75
MHC class II molecules are found on

A)neutrophils,monocytes,and macrophages.
B)dendritic cells,B cells,and helper T cells.
C)monocytes,helper T cells,and neutrophils.
D)B cells,macrophages,and dendritic cells.
E)B cells,C cells and D cells.
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76
Lymphocyte activation can occur in several ways.However,in all cases

A)lymphocytes must recognize an antigen.
B)helper T cells are activated first and they then stimulate other cells.
C)antigen-presenting cells process the antigen and present it to the lymphocytes.
D)cytokines released by the antigen stimulate the lymphocyte response.
E)antigens must be able to recognize the lymphocytes.
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77
The thymus is where ____ mature and become functional immune cells.

A)pre-T cells
B)pre-B cells
C)macrophages
D)null cells
E)C cells.
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78
____ are part of cell-mediated immunity while ____ are part of antibody-mediated immunity.

A)B cells,NK cells
B)Antibodies,antigens
C)T cells,B cells
D)Macrophages,antibodies
E)Neutrophils,monocytes
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79
Primary lymphatic organs include the

A)tonsils and spleen.
B)thymus and lymph nodes.
C)red bone marrow and thymus.
D)red bone marrow and lymph nodes.
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80
The MHC class I antigen complex displays a foreign antigen on the cell surface.This prompts the immune system to destroy

A)B cell clones.
B)extracellular antigens.
C)the displaying cell.
D)mature red blood cells.
E)the virus inside the cell,but not the cell.
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