Deck 19: Infectious Diseases Affecting the Respiratory Systems

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سؤال
Rheumatic fever is caused by ________.

A) a primary streptococcal infection with Streptococcus pyogenes
B) a combination of infection with Streptococcus pyogenes and the rheumatic fever virus
C) a secondary streptococcal infection with a different type of streptococcus
D) an immunological cross-reaction in which anti-streptococcal antibodies target the heart
E) both a primary viral infection and a secondary streptococcal infection
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سؤال
Which of the following is not part of the upper respiratory tract?

A) Mouth
B) Nasal cavity
C) Trachea
D) Pharynx
E) Larynx
سؤال
The most common type of virus leading to rhinitis is ________.

A) coronavirus
B) adenovirus
C) rhinovirus
D) herpes simplex virus
E) retrovirus
سؤال
What features of the respiratory system protect us from infection?

A) Nasal hairs
B) Cilia
C) Mucus
D) Macrophages
E) All of the choices are correct.
سؤال
Which of the following is not true of Streptococcus pyogenes?

A) Group A streptococcus
B) Gram positive
C) Forms spores
D) Sensitive to bacitracin
E) Beta hemolytic
سؤال
Virulence factors of Streptococcus pyogenes include ________.

A) polysaccharides on the cell wall
B) lipoteichoic acid
C) M proteins
D) hyaluronic acid capsule
E) All of the choices are correct.
سؤال
Normal biota of the lower respiratory tract include ________.

A) Corynebacterium
B) Candida albicans
C) Haemophilus influenzae
D) Staphylococcus aureus
E) None of the choices are correct.
سؤال
Cold viruses are transmitted by ________.

A) droplet contact and indirect contact
B) endogenous
C) direct contact
D) None of the choices are correct.
E) All of the choices are correct.
سؤال
Untreated streptococcal pharyngitis can lead to all of the following except ________.

A) scarlet fever
B) pertussis
C) rheumatic fever
D) glomerulonephritis
E) erythrogenic rash
سؤال
Which antibody is concentrated in the respiratory tract?

A) IgA
B) IgE
C) IgG
D) IgM
E) All of the choices are correct.
سؤال
Normal biota of the upper respiratory tract include ________.

A) Streptococcus pyogenes
B) Streptococcus pneumoniae
C) Neisseria meningitidis
D) alpha-hemolytic streptococci
E) All of the choices are correct.
سؤال
What is the function of normal biota of the respiratory tract?

A) Compete with pathogens for resources and space
B) Microbial antagonism
C) Provide antibodies
D) Both compete with pathogens for resources and space and microbial antagonism are correct.
E) Compete with pathogens for resources and space, microbial antagonism, and provide antibodies are all correct.
سؤال
Superantigens ________.

A) include streptolysin O
B) include erythrogenic toxin
C) induce production of tumor necrosis factor
D) can initiate a cascade of immune responses
E) All of the choices are correct.
سؤال
Streptococcal pharyngitis involves all of the following except ________.

A) a purulent exudate over the tonsils
B) it can lead to scarlet fever if it is an erythrogenic toxin-producing strain
C) it can lead to serious sequelae
D) it is viral in origin
E) it causes difficulty in swallowing and fever
سؤال
The most common mode of transmission for sinusitis is ________.

A) exotoxin
B) direct contact
C) indirect contact
D) endogenous
E) droplet contact
سؤال
The most common causative agent of otitis media is ________.

A) Aspergillus fumigatus
B) Haemophilus influenzae
C) Candida albicans
D) Corynebacterium
E) Streptococcus pneumoniae
سؤال
The bright red rash and fever of scarlet fever are due to ________.

A) enterotoxins
B) hemolysins
C) toxic shock syndrome toxin
D) exfoliative toxin
E) erythrogenic toxin
سؤال
Infection travels to the middle ear by way of the ________.

A) auditory canal
B) sinuses
C) nasal cavity
D) eustachian (auditory) tubes
E) subarachnoid space
سؤال
Normal biota of the upper respiratory tract include ________.

A) Aspergillis
B) Candida albicans
C) Haemophilus influenzae
D) Staphylococcus aureus
E) All of the choices are correct.
سؤال
Which of the following is not part of the lower respiratory system?

A) Alveoli
B) Bronchi
C) Bronchioles
D) Trachea
E) Sinuses
سؤال
Respiratory syncytial virus ________.

A) causes serious disease in infants 6 months old or younger
B) is highly contagious
C) is transmitted through droplet contact and fomite contamination
D) cannot be prevented by vaccination at this time
E) All of the choices are correct.
سؤال
All of the following pertain to tuberculosis except ________.

A) live bacilli can remain dormant in the lungs and reactivate later in life
B) symptoms of active TB include low-grade fever, coughing, fatigue, weight loss, and night sweats
C) lung infection can disseminate to many other organs in extrapulmonary TB
D) the BCG vaccine is used in other countries
E) antimicrobials cannot treat and cure tuberculosis
سؤال
Pertussis has the following characteristics except ________.

A) the disease progresses through several distinct stages
B) the catarrhal stage has persistent, hacking coughs with "whoops"
C) the early stage resembles a cold with nasal discharge and sneezing
D) DTaP immunization will prevent it
E) transmission is by droplet contact
سؤال
Which of the following is not true of influenza?

A) It has glycoprotein spikes of hemagglutinin (H) and neuraminidase (N).
B) Antigenic drift which changes the antigens to reduce immune recognition.
C) Antigenic shift causes changes in the RNA strands.
D) Symptoms are very similar to the common cold.
E) The virus can infect both humans and swine.
سؤال
Symptoms of influenza include ________.

A) nasal discharge, mild fever, and absence of cough
B) fever, diarrhea, and vomiting
C) fever, myalgia, sore throat, cough, and nasal discharge
D) fever, sore throat, rash, and cough
E) fever and pneumonia
سؤال
Which of the following is not a virulence factor of Bordetella pertussis?

A) Endotoxin
B) Tracheal cytotoxin
C) M protein
D) Pertussis toxin
E) Filamentous hemagglutinin
سؤال
The causative organism of whooping cough is ________.

A) Bordetella pertussis
B) Streptococcus pneumoniae
C) Haemophilus influenzae
D) Streptococcus pyogenes
E) Corynebacterium diphtheriae
سؤال
The enzyme associated with the influenza virus that hydrolyzes the protective mucous coating of the respiratory tract is ________.

A) catalase
B) reverse transcriptase
C) hyaluronidase
D) neuraminidase
E) kinase
سؤال
A diagnosis of tuberculosis involves a(n) ________.

A) chest X-ray
B) acid-fast stain of sputum
C) sputum culture
D) tuberculin skin test
E) All of the choices are correct.
سؤال
Influenza vaccines include all the following except ________.

A) an inactivated dead virus
B) the incorporation of usually three different strains
C) an attenuated nasal drops vaccine
D) the ability to provide lifelong immunity
E) an overall effectiveness of 70%−90%
سؤال
Which of the following causes a noncommunicable pulmonary infection that resembles tuberculosis?

A) Mycobacterium avium complex (MAC)
B) Mycobacterium kansasii
C) Mycobacterium scrofulaceum
D) Mycobacterium fortuitum complex
E) Mycobacterium marinum
سؤال
Which of the following is not true of whooping cough?

A) Secondary infections can occur during the convalescent phase
B) Caused by a small gram-positive rod
C) Incubation period is 3-21 days
D) Coldlike symptoms are common for the paroxysmal stage
E) An uncontrollable cough occurs during the paroxysmal stage
سؤال
Diphtherotoxin targets cells in the ________.

A) pharynx and lungs
B) lungs and heart
C) heart and brain
D) heart and nerves
E) lungs and nerves
سؤال
The major virulence factor of Corynebacterium diphtheriae that causes serious systemic effects is ________.

A) its capsules
B) metachromatic granules
C) an exotoxin
D) endospores
E) an endotoxin
سؤال
Formation of a pseudomembrane in the back of the throat is seen in ________.

A) diphtheria
B) pharyngitis
C) tuberculosis
D) pertussis
E) SARS
سؤال
The tubercles formed in primary tuberculosis are caused by an influx of ________.

A) neutrophils
B) basophils
C) mononuclear cells
D) polymorphonuclear leukocytes
E) antibodies
سؤال
Which of the following pertains to diphtheria?

A) Results in meningitis
B) Symptoms include vomiting and diarrhea
C) Can be transmitted from mother's birth canal to neonate
D) Prevented by the DTaP immunization
E) All of the choices are correct.
سؤال
Tuberculin skin testing ________.

A) injects PPD intradermally
B) uses a purified protein filtrate of Mycobacterium tuberculosis
C) will be positive if the person has had previous exposure to TB
D) will be positive if the person has active TB
E) All of the choices are correct.
سؤال
Extrapulmonary TB can involve the ________.

A) kidneys
B) long bones
C) spine
D) brain
E) All of the choices are correct.
سؤال
Which is not correct about Mycobacterium species?

A) All species are human pathogens.
B) Cell walls have waxy lipids.
C) They are acid fast.
D) Usually have a slow growth rate.
E) They are long, slender rods.
سؤال
Legionella pneumophila ________.

A) is easily killed by chlorine
B) often lives intracellularly in amoebas
C) is transmitted through the soil
D) always causes a severe pneumonia
E) is a gram-positive bacterium
سؤال
Secondary bacterial infections may occur with the common cold.
سؤال
Inhalation of respiratory secretions is involved in the transmission of the following except ________.

A) influenza
B) rhinitis
C) legionella
D) diphtheria
E) All of the choices involve respiratory secretions.
سؤال
Influenza is predominantly transmitted by the fecal-oral route.
سؤال
Respiratory syncytial virus is a major cause of global respiratory infection outbreaks in infants 6 months of age or younger.
سؤال
Influenza virus can exhibit constant mutation of viral glycoproteins called ________, or ________, a more serious phenomenon caused by the exchange of a viral gene with that of another influenza virus strain.

A) antigenic shift, antigenic drift
B) antigenic drift, antigenic shift
C) None of these are correct.
سؤال
Treatment for diphtheria requires only penicillin or erythromycin.
سؤال
The primary transmission route for acquiring agents of the common cold is by contact with hands and fomites contaminated with the nasal discharges of an infected person.
سؤال
Drug-resistant strains of Streptococcus pneumoniae are now treated with ________.

A) penicillin V
B) erythromycin
C) tetracyline
D) vancomycin
E) cefuroxime
سؤال
Streptococcus pneumoniae is ________.

A) alpha-hemolytic on blood agar
B) often referred to as pneumococcus
C) a gram-positive diplococcus with a capsule
D) most likely to cause infection in older adults
E) All of the choices are correct.
سؤال
Which disease involves transmission by aerosolized water from whirlpool spas, air conditioners, cooling towers, and supermarket vegetable misters?

A) Legionellosis
B) Pertussis
C) Brucellosis
D) Plague
E) Traveler's diarrhea
سؤال
An induration of less than 5 mm in the Mantoux test is negative for TB.
سؤال
People who have received the BCG immunization will generally have a negative tuberculin skin test.
سؤال
Pertussis outbreaks still occur in the United States.
سؤال
This opportunist is the most frequent cause of life-threatening pneumonia in AIDS patients.

A) Cryptococcus neoformans
B) Candida albicans
C) Malassezia furfur
D) Pneumocystis (carinii) jiroveci
E) None of the choices are correct.
سؤال
When the centers of tubercles break down into ________ lesions, they gradually heal by calcification that replaces normal lung tissue.

A) primary
B) secondary
C) necrotic caseous
D) granuloma
E) tertiary
سؤال
The highest incidence of histoplasmosis in the United States occurs in the ________.

A) Southeast
B) Southwest
C) East and Midwest
D) Northeast
E) Rocky Mountains
سؤال
Hantavirus has all of the following characteristics except ________.

A) a reservoir is human carriers
B) it is a zoonotic infection
C) the symptoms are abrupt fever, lung edema, respiratory distress, and hypotension
D) it is transmitted by aerosol transmission from rodent excreta
E) the first U.S. outbreak occurred in 1993 in the Southwest
سؤال
Characteristics of Histoplasma capsulatum include ________.

A) it grows in moist soil; rich in nitrogen from bird and bat droppings
B) it is a yeast with a capsule
C) it is commonly found in the southwestern United States
D) it always results in severe infections
E) its transmission occurs through water droplets
سؤال
Antibiotic treatment for otitis media is standard procedure today.
سؤال
Which of the following pairs of defense mechanisms is mismatched?

A) Complement activation - third line of defense
B) Ciliated epithelium - first line of defense
C) Secretory IgA - third line of defense
D) Antimicrobial peptides - second line of defense
E) Coughing - first line of defense
سؤال
The major reservoir for the hantavirus is the deer mouse.
سؤال
Anatomical features situated below the tonsils are considered the lower respiratory tract.
سؤال
A paroxysmal cough is associated with Legionnaires' disease.
سؤال
Suspecting the patient is infected with influenza, the nurse prepares to obtain which of the following specimens for rapid testing at an external laboratory?

A) Blood
B) Cerebrospinal fluid
C) Nasal swab
D) Skin scraping
سؤال
Extensively drug-resistant tuberculosis, while harder to treat because some antibiotics are ineffective, has a similar prognosis and recovery rate compared to nonresistant tuberculosis.
سؤال
The rapid microbial analysis is negative for group A Streptococcus and reveals the presence of only normal biota in the patient specimen. Based upon this information, all of the following microbes can be ruled out in the diagnosis except ________.

A) Streptococcus pyogenes
B) Staphylococcus aureus
C) Haemophilus influenzae
D) Influenza A
سؤال
Legionellosis is a zoonosis.
سؤال
The patient's clinical condition deteriorates rapidly. Even without laboratory confirmation of the pathogen, the provider orders which course of treatment?

A) Administration of rimantadine to treat the patient's suspected influenza
B) Administration of trimethoprim-sulfamethoxazole to treat the patient's suspected PCP
C) Administration of ciprofloxacin to treat the patient's suspected pulmonary anthrax
D) Administration of antitoxin to treat the patient's suspected diphtheria
سؤال
The main contributing factor to the evolution of MDR-TB is ________.

A) the slow growth of Mycobacterium tuberculosis requires antibiotic therapy for months rather than days, which is hard to sustain in some populations; cutting the regimen short allows the resistant bacteria to flourish
B) the organisms that develop multidrug resistance have a different cell wall composition to the drug-susceptible organisms
C) certain species of Mycobacterium tuberculosis are able to undergo bacterial transformation at a faster rate than other species, resulting in the transfer of resistance genes
D) the abundance of antibiotics available in the United States and other developed countries makes it a particular problem for resistant strains to emerge in those parts of the world
سؤال
Assess the following statements and determine which one is incorrect regarding antigenic shift.

A) The influenza virus genome mutates over time changing the amino acid sequence of the envelope glycoproteins. Each encounter with a new version of the virus requires activation of naive lymphocytes rather than memory cells, which is the reason we receive a new vaccination each year.
B) The influenza genome contains 10 genes distributed on 8 separate RNA strands. These strands can be exchanged between different viruses.
C) Some virus strains infect birds and swine, some infect swine and humans. If the strain that infects swine and humans exchanges strands with a bird flu strain while in a swine host cell, that virus can go on to infect a human who will have no recognition for the bird protein.
D) If a new strain of virus emerged from an antigenic shift event, a vaccine different to the annual flu vaccine would have to be administered because the proteins coded for by the new strain would be different to those made as a result of antigenic drift.
سؤال
The laboratory findings are discussed with the medical team. Culturing on specialized media will be required for definitive identification of the microbe. Which medium will the technicians use to culture this suspected pathogen?

A) Tellurite medium
B) Mannitol salt agar
C) Eosin methylene blue agar
D) None of the choices are correct. This pathogen must be propagated using tissue culture.
سؤال
Medical professionals actually observe MDR-TB patients take their medicine through a program called DOT.
سؤال
Examination of the throat swab specimen reveals distinct gram-positive club-shaped bacilli. The laboratory technician immediately contacts the medical team and begins the process of submitting specimens for PCR testing to the CDC. The suspected pathogen is ________.

A) influenza A
B) Pneumocystis (carinii) jiroveci
C) Corynebacterium diphtheriae
D) Bacillus anthracis
سؤال
The RN educates the patient about diphtheria. In explaining the role of exotoxin in the pathogenesis of the disease, the nurse correctly states that the exotoxin ________.

A) is the major virulence factor of the disease
B) is isolated to the respiratory tract, causing upper and lower respiratory tract symptoms
C) is released in the blood, causing systemic effects
D) is the major virulence factor of the disease and is released in the blood, causing systemic effects
سؤال
The nurse assesses the patient's medical history and notes that she has not received routine medical screening and treatment in the past 15 years. This patient could avoided this preventable disease by staying current with which vaccination?

A) MMR
B) Influenza
C) Td
D) HPV
سؤال
The laboratory findings report that the child is infected with influenza B virus. Which of the following medications would the nurse expect to be ordered for this child?

A) Penicillin
B) No medication
C) Acyclovir
D) Oseltamivir
سؤال
Antigenic drift differs from antigenic shift in that antigenic drift reflects the exchange of RNA strands between different virus strains within a common host cell, whereas antigenic shift is the gradual mutation over time of the glycoproteins on the viral envelope that bind to immune cells.
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ملء الشاشة (f)
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Deck 19: Infectious Diseases Affecting the Respiratory Systems
1
Rheumatic fever is caused by ________.

A) a primary streptococcal infection with Streptococcus pyogenes
B) a combination of infection with Streptococcus pyogenes and the rheumatic fever virus
C) a secondary streptococcal infection with a different type of streptococcus
D) an immunological cross-reaction in which anti-streptococcal antibodies target the heart
E) both a primary viral infection and a secondary streptococcal infection
an immunological cross-reaction in which anti-streptococcal antibodies target the heart
2
Which of the following is not part of the upper respiratory tract?

A) Mouth
B) Nasal cavity
C) Trachea
D) Pharynx
E) Larynx
Trachea
3
The most common type of virus leading to rhinitis is ________.

A) coronavirus
B) adenovirus
C) rhinovirus
D) herpes simplex virus
E) retrovirus
rhinovirus
4
What features of the respiratory system protect us from infection?

A) Nasal hairs
B) Cilia
C) Mucus
D) Macrophages
E) All of the choices are correct.
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5
Which of the following is not true of Streptococcus pyogenes?

A) Group A streptococcus
B) Gram positive
C) Forms spores
D) Sensitive to bacitracin
E) Beta hemolytic
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6
Virulence factors of Streptococcus pyogenes include ________.

A) polysaccharides on the cell wall
B) lipoteichoic acid
C) M proteins
D) hyaluronic acid capsule
E) All of the choices are correct.
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7
Normal biota of the lower respiratory tract include ________.

A) Corynebacterium
B) Candida albicans
C) Haemophilus influenzae
D) Staphylococcus aureus
E) None of the choices are correct.
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8
Cold viruses are transmitted by ________.

A) droplet contact and indirect contact
B) endogenous
C) direct contact
D) None of the choices are correct.
E) All of the choices are correct.
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9
Untreated streptococcal pharyngitis can lead to all of the following except ________.

A) scarlet fever
B) pertussis
C) rheumatic fever
D) glomerulonephritis
E) erythrogenic rash
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10
Which antibody is concentrated in the respiratory tract?

A) IgA
B) IgE
C) IgG
D) IgM
E) All of the choices are correct.
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11
Normal biota of the upper respiratory tract include ________.

A) Streptococcus pyogenes
B) Streptococcus pneumoniae
C) Neisseria meningitidis
D) alpha-hemolytic streptococci
E) All of the choices are correct.
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12
What is the function of normal biota of the respiratory tract?

A) Compete with pathogens for resources and space
B) Microbial antagonism
C) Provide antibodies
D) Both compete with pathogens for resources and space and microbial antagonism are correct.
E) Compete with pathogens for resources and space, microbial antagonism, and provide antibodies are all correct.
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13
Superantigens ________.

A) include streptolysin O
B) include erythrogenic toxin
C) induce production of tumor necrosis factor
D) can initiate a cascade of immune responses
E) All of the choices are correct.
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14
Streptococcal pharyngitis involves all of the following except ________.

A) a purulent exudate over the tonsils
B) it can lead to scarlet fever if it is an erythrogenic toxin-producing strain
C) it can lead to serious sequelae
D) it is viral in origin
E) it causes difficulty in swallowing and fever
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15
The most common mode of transmission for sinusitis is ________.

A) exotoxin
B) direct contact
C) indirect contact
D) endogenous
E) droplet contact
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16
The most common causative agent of otitis media is ________.

A) Aspergillus fumigatus
B) Haemophilus influenzae
C) Candida albicans
D) Corynebacterium
E) Streptococcus pneumoniae
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17
The bright red rash and fever of scarlet fever are due to ________.

A) enterotoxins
B) hemolysins
C) toxic shock syndrome toxin
D) exfoliative toxin
E) erythrogenic toxin
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18
Infection travels to the middle ear by way of the ________.

A) auditory canal
B) sinuses
C) nasal cavity
D) eustachian (auditory) tubes
E) subarachnoid space
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19
Normal biota of the upper respiratory tract include ________.

A) Aspergillis
B) Candida albicans
C) Haemophilus influenzae
D) Staphylococcus aureus
E) All of the choices are correct.
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20
Which of the following is not part of the lower respiratory system?

A) Alveoli
B) Bronchi
C) Bronchioles
D) Trachea
E) Sinuses
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21
Respiratory syncytial virus ________.

A) causes serious disease in infants 6 months old or younger
B) is highly contagious
C) is transmitted through droplet contact and fomite contamination
D) cannot be prevented by vaccination at this time
E) All of the choices are correct.
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22
All of the following pertain to tuberculosis except ________.

A) live bacilli can remain dormant in the lungs and reactivate later in life
B) symptoms of active TB include low-grade fever, coughing, fatigue, weight loss, and night sweats
C) lung infection can disseminate to many other organs in extrapulmonary TB
D) the BCG vaccine is used in other countries
E) antimicrobials cannot treat and cure tuberculosis
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23
Pertussis has the following characteristics except ________.

A) the disease progresses through several distinct stages
B) the catarrhal stage has persistent, hacking coughs with "whoops"
C) the early stage resembles a cold with nasal discharge and sneezing
D) DTaP immunization will prevent it
E) transmission is by droplet contact
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24
Which of the following is not true of influenza?

A) It has glycoprotein spikes of hemagglutinin (H) and neuraminidase (N).
B) Antigenic drift which changes the antigens to reduce immune recognition.
C) Antigenic shift causes changes in the RNA strands.
D) Symptoms are very similar to the common cold.
E) The virus can infect both humans and swine.
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25
Symptoms of influenza include ________.

A) nasal discharge, mild fever, and absence of cough
B) fever, diarrhea, and vomiting
C) fever, myalgia, sore throat, cough, and nasal discharge
D) fever, sore throat, rash, and cough
E) fever and pneumonia
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26
Which of the following is not a virulence factor of Bordetella pertussis?

A) Endotoxin
B) Tracheal cytotoxin
C) M protein
D) Pertussis toxin
E) Filamentous hemagglutinin
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27
The causative organism of whooping cough is ________.

A) Bordetella pertussis
B) Streptococcus pneumoniae
C) Haemophilus influenzae
D) Streptococcus pyogenes
E) Corynebacterium diphtheriae
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28
The enzyme associated with the influenza virus that hydrolyzes the protective mucous coating of the respiratory tract is ________.

A) catalase
B) reverse transcriptase
C) hyaluronidase
D) neuraminidase
E) kinase
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29
A diagnosis of tuberculosis involves a(n) ________.

A) chest X-ray
B) acid-fast stain of sputum
C) sputum culture
D) tuberculin skin test
E) All of the choices are correct.
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30
Influenza vaccines include all the following except ________.

A) an inactivated dead virus
B) the incorporation of usually three different strains
C) an attenuated nasal drops vaccine
D) the ability to provide lifelong immunity
E) an overall effectiveness of 70%−90%
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31
Which of the following causes a noncommunicable pulmonary infection that resembles tuberculosis?

A) Mycobacterium avium complex (MAC)
B) Mycobacterium kansasii
C) Mycobacterium scrofulaceum
D) Mycobacterium fortuitum complex
E) Mycobacterium marinum
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32
Which of the following is not true of whooping cough?

A) Secondary infections can occur during the convalescent phase
B) Caused by a small gram-positive rod
C) Incubation period is 3-21 days
D) Coldlike symptoms are common for the paroxysmal stage
E) An uncontrollable cough occurs during the paroxysmal stage
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33
Diphtherotoxin targets cells in the ________.

A) pharynx and lungs
B) lungs and heart
C) heart and brain
D) heart and nerves
E) lungs and nerves
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34
The major virulence factor of Corynebacterium diphtheriae that causes serious systemic effects is ________.

A) its capsules
B) metachromatic granules
C) an exotoxin
D) endospores
E) an endotoxin
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35
Formation of a pseudomembrane in the back of the throat is seen in ________.

A) diphtheria
B) pharyngitis
C) tuberculosis
D) pertussis
E) SARS
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36
The tubercles formed in primary tuberculosis are caused by an influx of ________.

A) neutrophils
B) basophils
C) mononuclear cells
D) polymorphonuclear leukocytes
E) antibodies
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37
Which of the following pertains to diphtheria?

A) Results in meningitis
B) Symptoms include vomiting and diarrhea
C) Can be transmitted from mother's birth canal to neonate
D) Prevented by the DTaP immunization
E) All of the choices are correct.
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38
Tuberculin skin testing ________.

A) injects PPD intradermally
B) uses a purified protein filtrate of Mycobacterium tuberculosis
C) will be positive if the person has had previous exposure to TB
D) will be positive if the person has active TB
E) All of the choices are correct.
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39
Extrapulmonary TB can involve the ________.

A) kidneys
B) long bones
C) spine
D) brain
E) All of the choices are correct.
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40
Which is not correct about Mycobacterium species?

A) All species are human pathogens.
B) Cell walls have waxy lipids.
C) They are acid fast.
D) Usually have a slow growth rate.
E) They are long, slender rods.
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41
Legionella pneumophila ________.

A) is easily killed by chlorine
B) often lives intracellularly in amoebas
C) is transmitted through the soil
D) always causes a severe pneumonia
E) is a gram-positive bacterium
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42
Secondary bacterial infections may occur with the common cold.
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43
Inhalation of respiratory secretions is involved in the transmission of the following except ________.

A) influenza
B) rhinitis
C) legionella
D) diphtheria
E) All of the choices involve respiratory secretions.
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44
Influenza is predominantly transmitted by the fecal-oral route.
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45
Respiratory syncytial virus is a major cause of global respiratory infection outbreaks in infants 6 months of age or younger.
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46
Influenza virus can exhibit constant mutation of viral glycoproteins called ________, or ________, a more serious phenomenon caused by the exchange of a viral gene with that of another influenza virus strain.

A) antigenic shift, antigenic drift
B) antigenic drift, antigenic shift
C) None of these are correct.
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47
Treatment for diphtheria requires only penicillin or erythromycin.
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48
The primary transmission route for acquiring agents of the common cold is by contact with hands and fomites contaminated with the nasal discharges of an infected person.
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49
Drug-resistant strains of Streptococcus pneumoniae are now treated with ________.

A) penicillin V
B) erythromycin
C) tetracyline
D) vancomycin
E) cefuroxime
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50
Streptococcus pneumoniae is ________.

A) alpha-hemolytic on blood agar
B) often referred to as pneumococcus
C) a gram-positive diplococcus with a capsule
D) most likely to cause infection in older adults
E) All of the choices are correct.
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51
Which disease involves transmission by aerosolized water from whirlpool spas, air conditioners, cooling towers, and supermarket vegetable misters?

A) Legionellosis
B) Pertussis
C) Brucellosis
D) Plague
E) Traveler's diarrhea
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52
An induration of less than 5 mm in the Mantoux test is negative for TB.
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53
People who have received the BCG immunization will generally have a negative tuberculin skin test.
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54
Pertussis outbreaks still occur in the United States.
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55
This opportunist is the most frequent cause of life-threatening pneumonia in AIDS patients.

A) Cryptococcus neoformans
B) Candida albicans
C) Malassezia furfur
D) Pneumocystis (carinii) jiroveci
E) None of the choices are correct.
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56
When the centers of tubercles break down into ________ lesions, they gradually heal by calcification that replaces normal lung tissue.

A) primary
B) secondary
C) necrotic caseous
D) granuloma
E) tertiary
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57
The highest incidence of histoplasmosis in the United States occurs in the ________.

A) Southeast
B) Southwest
C) East and Midwest
D) Northeast
E) Rocky Mountains
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58
Hantavirus has all of the following characteristics except ________.

A) a reservoir is human carriers
B) it is a zoonotic infection
C) the symptoms are abrupt fever, lung edema, respiratory distress, and hypotension
D) it is transmitted by aerosol transmission from rodent excreta
E) the first U.S. outbreak occurred in 1993 in the Southwest
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59
Characteristics of Histoplasma capsulatum include ________.

A) it grows in moist soil; rich in nitrogen from bird and bat droppings
B) it is a yeast with a capsule
C) it is commonly found in the southwestern United States
D) it always results in severe infections
E) its transmission occurs through water droplets
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60
Antibiotic treatment for otitis media is standard procedure today.
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61
Which of the following pairs of defense mechanisms is mismatched?

A) Complement activation - third line of defense
B) Ciliated epithelium - first line of defense
C) Secretory IgA - third line of defense
D) Antimicrobial peptides - second line of defense
E) Coughing - first line of defense
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62
The major reservoir for the hantavirus is the deer mouse.
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63
Anatomical features situated below the tonsils are considered the lower respiratory tract.
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64
A paroxysmal cough is associated with Legionnaires' disease.
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65
Suspecting the patient is infected with influenza, the nurse prepares to obtain which of the following specimens for rapid testing at an external laboratory?

A) Blood
B) Cerebrospinal fluid
C) Nasal swab
D) Skin scraping
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66
Extensively drug-resistant tuberculosis, while harder to treat because some antibiotics are ineffective, has a similar prognosis and recovery rate compared to nonresistant tuberculosis.
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67
The rapid microbial analysis is negative for group A Streptococcus and reveals the presence of only normal biota in the patient specimen. Based upon this information, all of the following microbes can be ruled out in the diagnosis except ________.

A) Streptococcus pyogenes
B) Staphylococcus aureus
C) Haemophilus influenzae
D) Influenza A
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68
Legionellosis is a zoonosis.
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69
The patient's clinical condition deteriorates rapidly. Even without laboratory confirmation of the pathogen, the provider orders which course of treatment?

A) Administration of rimantadine to treat the patient's suspected influenza
B) Administration of trimethoprim-sulfamethoxazole to treat the patient's suspected PCP
C) Administration of ciprofloxacin to treat the patient's suspected pulmonary anthrax
D) Administration of antitoxin to treat the patient's suspected diphtheria
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70
The main contributing factor to the evolution of MDR-TB is ________.

A) the slow growth of Mycobacterium tuberculosis requires antibiotic therapy for months rather than days, which is hard to sustain in some populations; cutting the regimen short allows the resistant bacteria to flourish
B) the organisms that develop multidrug resistance have a different cell wall composition to the drug-susceptible organisms
C) certain species of Mycobacterium tuberculosis are able to undergo bacterial transformation at a faster rate than other species, resulting in the transfer of resistance genes
D) the abundance of antibiotics available in the United States and other developed countries makes it a particular problem for resistant strains to emerge in those parts of the world
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71
Assess the following statements and determine which one is incorrect regarding antigenic shift.

A) The influenza virus genome mutates over time changing the amino acid sequence of the envelope glycoproteins. Each encounter with a new version of the virus requires activation of naive lymphocytes rather than memory cells, which is the reason we receive a new vaccination each year.
B) The influenza genome contains 10 genes distributed on 8 separate RNA strands. These strands can be exchanged between different viruses.
C) Some virus strains infect birds and swine, some infect swine and humans. If the strain that infects swine and humans exchanges strands with a bird flu strain while in a swine host cell, that virus can go on to infect a human who will have no recognition for the bird protein.
D) If a new strain of virus emerged from an antigenic shift event, a vaccine different to the annual flu vaccine would have to be administered because the proteins coded for by the new strain would be different to those made as a result of antigenic drift.
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72
The laboratory findings are discussed with the medical team. Culturing on specialized media will be required for definitive identification of the microbe. Which medium will the technicians use to culture this suspected pathogen?

A) Tellurite medium
B) Mannitol salt agar
C) Eosin methylene blue agar
D) None of the choices are correct. This pathogen must be propagated using tissue culture.
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73
Medical professionals actually observe MDR-TB patients take their medicine through a program called DOT.
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74
Examination of the throat swab specimen reveals distinct gram-positive club-shaped bacilli. The laboratory technician immediately contacts the medical team and begins the process of submitting specimens for PCR testing to the CDC. The suspected pathogen is ________.

A) influenza A
B) Pneumocystis (carinii) jiroveci
C) Corynebacterium diphtheriae
D) Bacillus anthracis
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75
The RN educates the patient about diphtheria. In explaining the role of exotoxin in the pathogenesis of the disease, the nurse correctly states that the exotoxin ________.

A) is the major virulence factor of the disease
B) is isolated to the respiratory tract, causing upper and lower respiratory tract symptoms
C) is released in the blood, causing systemic effects
D) is the major virulence factor of the disease and is released in the blood, causing systemic effects
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76
The nurse assesses the patient's medical history and notes that she has not received routine medical screening and treatment in the past 15 years. This patient could avoided this preventable disease by staying current with which vaccination?

A) MMR
B) Influenza
C) Td
D) HPV
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77
The laboratory findings report that the child is infected with influenza B virus. Which of the following medications would the nurse expect to be ordered for this child?

A) Penicillin
B) No medication
C) Acyclovir
D) Oseltamivir
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78
Antigenic drift differs from antigenic shift in that antigenic drift reflects the exchange of RNA strands between different virus strains within a common host cell, whereas antigenic shift is the gradual mutation over time of the glycoproteins on the viral envelope that bind to immune cells.
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