Deck 42: Thyroid and Antithyroid Drugs

Question 1

Which of the following drugs interacts with thyroperoxidase and NADPH oxidases to inhibit the organification of iodide?

A) Perchlorate
B) Propylthiouracil
C) L-thyroxine
D) Lithium
E) Iopanoate

Answer 1

Propylthiouracil

Question 2

Why are corticosteroids often included in the treatment of hyperthyroidism?

A) To stabilize the erratic blood sugars of hyperthyroidism
B) To increase the catabolism of T₄ to T₃
C) As an antiinflammatory agent for the thyroid
D) To counteract the increased delta-4 steroid reductase activity
E) To displace thyroxine-binding globulin from plasma proteins

Answer 2

To counteract the increased delta-4 steroid reductase activity