Deck 21: Diuretic Drugs

Question 1

The location of the mechanism that leads to hypokalemia with many diuretics is located in the:

A) Glomerulus
B) Proximal convoluted tubule
C) Descending loop
D) Ascending loop
E) Collecting tubule

Answer 1

Collecting tubule

Question 2

Diuretic resistance after chronic loop diuretic administration is due to:

A) Increase in the transport of organic cations from the blood to the urine
B) Increased Na⁺/K⁺ -ATPase activity
C) A decrease in Na⁺ reabsorption by distal tubule cells
D) Decreased osmotic load at the distal tubule
E) Decreased Na⁺/K⁺ -ATPase activity

Answer 2

Increased Na⁺/K⁺ -ATPase activity

Question 3

Carbonic anhydrase inhibitors promote the excretion of Na⁺ and HCO^-₃ whereas thiazide diuretics promote:

A)Excretion of Na⁺, Cl^-, and Ca⁺⁺
B)Excretion of Na⁺ and Cl^- while diminishing Ca⁺⁺ excretion
C)Excretion of Na⁺, Cl^-, Ca⁺⁺, and Mg⁺⁺
D)Excretion of Na⁺ and Cl^- while reabsorbing Mg⁺⁺
E)Excretion of Na⁺ while diminishing Cl^- excretion

Answer 3

Excretion of Na⁺ and Cl^- while diminishing Ca⁺⁺ excretion