Deck 2: Pharmacokinetics: Absorption, Distribution, Metabolism, and Elimination

Question 1

Drugs commonly undergo all of the following types of metabolism in the liver EXCEPT FOR:

A) Polymerization
B) Conjugation
C) Oxidation
D) Reduction
E) Hydrolysis

Answer 1

Polymerization

Question 2

Drugs commonly undergo all of the following types of metabolism in the liver EXCEPT FOR:

A) Polymerization
B) Conjugation
C) Oxidation
D) Reduction
E) Hydrolysis

Answer 2

Polymerization

Question 3

Which of the following features of a drug would enhance its uptake in the GI tract?

A) Polar
B) Water soluble
C) Ionized
D) Low molecular weight
E) Low concentration gradient

Answer 3

Low molecular weight

Question 4

Which organ contains predominantly tight intercellular junctions, thereby restricting its uptake of drugs?

A) Kidney
B) Liver
C) Brain
D) Heart
E) Lungs

Question 5

Which organ contains predominantly tight intercellular junctions, thereby restricting its uptake of drugs?

A) Kidney
B) Liver
C) Brain
D) Heart
E) Lungs