Deck 37: Pediatric Solid Tumors

Question 1

16)Which pediatric cancer occurs in the testes and ovaries?

A) Germ cell tumor
B) Neuroblastoma
C) Rhabdomyosarcoma
D) Wilms' tumor

Answer 1

A
According to embryologic development, benign and malignant germ cell tumors can occur anywhere in the midline-from the CNS through the mediastinum, retroperitoneum, and down to the ovaries and testicles.

Question 2

15)Which pediatric cancer occurs in the sympathetic nervous system ganglia?

A) Medulloblastoma
B) Neuroblastoma
C) Primary brain lesions
D) Retinoblastoma

Answer 2

B
Neuroblastoma is a small, round, blue cell tumor derived from cells of neural crest origin.These cells migrate embryologically to form paravertebral sympathetic ganglia, the adrenal medulla, and peripheral nerves.

Question 3

17)Wilms' tumors are cancers of which organ?

A) Kidney
B) Bone
C) Skeletal muscle
D) Smooth muscle

Answer 3

A
Wilms' tumor is a malignant embryonal cancer of the kidney.

Question 4

13)Which area is least likely to develop rhabdomyosarcoma?

A) Testis
B) Head and neck
C) Lower extremity
D) Upper extremity

Question 5

7)The craniospinal treatment technique is used to treat what specific type of pediatric cancer?

A) Medulloblastoma
B) Neuroblastoma
C) Rhabdomyosarcoma
D) Retinoblastoma

Question 6

12)Which pediatric cancer has the best overall survival?

A) ALL
B) Neuroblastoma
C) Wilms' tumor
D) HD

Question 7

2)Children are most likely to develop which type of leukemia?

A) ALL
B) AML
C) CLL
D) CML

Question 8

3)Ewing sarcomas are cancers of which organ?

A) Kidney
B) Bone
C) Skeletal muscle
D) Smooth muscle

Question 9

6)Treatment of rhabdomyosarcoma with radiation therapy is most effective when the cancer is located in the _______________.

A) orbit
B) bladder
C) skeletal muscle
D) kidney

Question 10

19)Which pediatric brain tumor often mimics medulloblastomas?

A) Ependymomas
B) Low-grade astrocytomas
C) High-grade astrocytomas
D) CNS germ cell tumors

Question 11

8)Which pediatric cancer is closely associated to nephroblastomatoses?

A) Ewing sarcoma
B) Medulloblastoma
C) Rhabdomyosarcoma
D) Wilms' tumor

Question 12

11)What is the most common intracranial tumor in children?

A) Medulloblastoma
B) Metastatic lesion
C) Astrocytoma
D) Craniopharyngioma

Question 13

9)Trilateral retinoblastoma includes cancer of which other cranial structure?

A) Pituitary gland
B) Pineal gland
C) Parotid gland
D) Paranasal sinuses

Question 14

5)Successful treatment of Langerhans cell histiocytosis requires what dose?

A) 200 to 400 cGy
B) 400 to 1200 cGy
C) 1500 to 2500 cGy
D) Greater than 4000 cGy

Question 15

18)Medulloblastomas typically begin in which area of the brain?

A) Brain stem
B) Cerebellum
C) Cerebrum
D) Hypothalamus

Question 16

4)Rhabdomyosarcomas are cancers of which organ?

A) Kidney
B) Bone
C) Brain
D) Mesenchymal

Question 17

10)What is the most common presenting symptom of a soft tissue sarcoma of the extremity?

A) Pain
B) Mass
C) Loss of mobility
D) Headache

Question 18

20)To what dose are medulloblastomas traditionally treated?

A) 2600 cGy
B) 3600 cGy
C) 4600 cGy
D) 5600 cGy
E) 6600 cGy

Question 19

1)Which of the following cancers would most likely be seen in a child?

A) Retinoblastoma
B) Primary brain
C) Osteosarcoma
D) Hodgkin's disease (HD)

Question 20

14)Which pediatric cancer spreads through the cerebrospinal fluid (CSF)?

A) Leukemia
B) Medulloblastoma
C) Neuroblastoma
D) Retinoblastoma

Question 21

23)Pituitary adenomas in children that are not successfully managed by surgery and hormonal suppression may be treated with radiation using which of the following?

A) Single-field electrons
B) Multiple-field photons
C) HDR brachytherapy
D) Multiple-field electrons

Question 22

21)The most common pediatric cancer is _________________.

A) medulloblastoma
B) retinoblastoma
C) acute leukemia
D) Wilms' tumor

Question 23

22)Keloids may be treated by surgical resection and adjuvant radiation therapy to doses of ____________ cGy.

A) 900 to 1200
B) 2000 to 3000
C) 3500 to 4500
D) 4500 to 5000