Deck 6: Medicine Formulations, Storage and Routes of Administration

Question 1

Following buccal administration,a drug:

A) travels along the gastrointestinal system.
B) goes directly to the hepatic portal circulation.
C) is absorbed directly into blood vessels.
D) is broken down by the stomach.

Answer 1

is absorbed directly into blood vessels.

Question 2

Eye drops are made isotonic to:

A) avoid pain or discomfort on application.
B) prevent infection.
C) prevent an increase in intraocular pressure.
D) prevent trachoma.

Answer 2

avoid pain or discomfort on application.

Question 3

Is it problematic to administer heparin via intramuscular injection?

A) No, intramuscular and subcutaneous administration are both safe and effective.
B) No, as long as the dose is appropriate.
C) Yes, it can cause a haematoma to form.
D) Yes, limited blood flow to skeletal muscles causes reduced bioavailability of the drug.

Answer 3

Yes, it can cause a haematoma to form.

Question 4

Laxative enemas are hypertonic in order to:

A) draw water into the lower gastrointestinal tract to soften stool.
B) dissolve faecal matter to enable it to be excreted.
C) improve the fluid balance of the client.
D) bulk up the faeces in order to minimise diarrhoea.

Question 5

Intrathecal injection is a mode of drug delivery into

A) blood.
B) lymph nodes.
C) cerebrospinal fluid.
D) synovial fluid.

Question 6

After administering ear drops,to allow the medication to disperse and absorb,the client should:

A) not talk for 5 minutes.
B) lie down with the affected ear facing up for about 10 minutes.
C) lie down flat for 10 minutes.
D) sit for 5 minutes.

Question 7

Which is true of a linctus?

A) It needs to be stored at or below 25°C.
B) It is administered without water.
C) It is a viscous liquid with expectorant, sedating and cough-suppressing properties.
D) All of the above.

Question 8

Which of the following routes of drug administration is recommended for a rapid drug effect?

A) Intradermal
B) Intravenous
C) Oral
D) Topical

Question 9

In children over the age of 3 years and adults,for aural administration the auricle is pulled:

A) down and back.
B) up and back.
C) down and outwards.
D) up and outwards.

Question 10

Ointments are lipid-based preparations that act like an occlusive dressing to:

A) completely shut out the skin from the air but allow sweating to still occur.
B) partially shut out the skin from the air but allow sweating to still occur.
C) partially shut out the skin from the air and prevent sweating.
D) completely shut out the skin from the air and prevent sweating.

Question 11

Administering enteric-coated medications via a nasogastric tube is:

A) usually alright if a large flush of water is given afterwards.
B) not advisable as medications administered via a nasogastric tube need to be crushed.
C) standard practice.
D) acceptable as long as the crushed tablet is not mixed with other medications.

Question 12

Suppositories,in general,when inserted into the lower third of the rectum:

A) always have a fast onset of action.
B) avoid the hepatic first pass.
C) are useful for ulcerative colitis.
D) are for laxative use only.

Question 13

Sublingual administration of a drug always ensures:

A) rapid action.
B) avoidance of hepatic first pass.
C) minimal adverse effects.
D) all of the above.

Question 14

A drug formulated into a(n)________ will penetrate the deeper layers of the skin most effectively.

A) lotion
B) gel
C) ointment
D) cream

Question 15

Which of the following injections involves drug administration to a highly vascular area of the body?

A) Subcutaneous injection
B) Intradermal injection
C) Intrathecal injection
D) Intramuscular injection

Question 16

Which of the following respiratory devices are NOT effective for use in acute exacerbation of asthma?

A) Metered-dose inhalers
B) Spacer devices
C) Nebulisers
D) Dry powder inhalers

Question 17

For best results when administering nystatin oral drops,you should do all of the following EXCEPT:

A) place it under the tongue.
B) hold it in the mouth for as long as possible.
C) swallow it straight away.
D) place it in the buccal cavity.

Question 18

To avoid hydrolysis of aspirin tablets,the container should be kept in:

A) the bathroom.
B) the kitchen.
C) a coat pocket.
D) a cool, dry place.

Question 19

Drugs administered transdermally must be:

A) lipophilic.
B) hydrophilic.
C) lipophobic.
D) amphipathic.

Question 20

Following use of a nebuliser unit:

A) dismantle the unit, rinse and shake to allow to dry.
B) pack it away in the client's bedside drawer.
C) dismantle the unit, rinse and towel dry.
D) leave it hanging by the client's bedside.

Question 21

The deltoid muscle is more vascular than the gluteus muscle,so it is possible to inject a large volume (exceeding 1 mL)of drug into the deltoid muscle.

Question 22

Drugs of biological origin such as vaccine preparations need to be stored

A) between 25°C and 37°C.
B) at room temperature.
C) between 10°C and 20°C.
D) between 0°C and 4°C.

Question 23

The shelf life of eye drops after opening the container is:

A) 12 days.
B) 24 days.
C) 28 days.
D) 36 days.

Question 24

The shelf life of a reconstituted penicillin mixture for oral use is:

A) 5 days.
B) 7 days.
C) 9 days.
D) 12 days.

Question 25

Storing biological products,for example insulin at 0-4°C,prevents:

A) proliferation.
B) pain on administration.
C) medication errors.
D) denaturation.

Question 26

Sustained or controlled-release medication should not be crushed or chewed.

Question 27

What is the rationale for lying down when inserting a pessary with an applicator and remaining in a supine position for approximately 20 minutes?

Question 28

There is a risk of damage to the large sciatic nerve when administering a drug by intramuscular injection into the gluteus muscle.

Question 29

Nasal preparations are not absorbed systemically.

Question 30

What effect does exercise have on absorption of a drug that is administered by intramuscular injection?

Question 31

The shelf life of glyceryl trinitrate tablets after opening the container is:

A) 80 days.
B) 85 days.
C) 90 days.
D) 100 days.