Question 1

Drugs that inhibit the synaptic serotonin reuptake are used for:&#10;A) autism.&#10;B) depression.&#10;C) glaucoma.&#10;D) termination of pregnancy.

Accepted Answer

Drugs that inhibit the synaptic serotonin reuptake, also known as SSRIs, are commonly used for the treatment of depression. These drugs increase the levels of serotonin in the brain, which in turn can help regulate mood and alleviate symptoms of depression.

Question 2

5-HT? receptor antagonists have been used for:&#10;A) nausea.&#10;B) somnolence.&#10;C) REMS sleep disorder.&#10;D) GERD.

Accepted Answer

5-HT₃ receptor antagonists are commonly used as anti-emetic drugs for the treatment of nausea. They work by blocking serotonin receptors in the gut and in the brain that are responsible for triggering the vomiting reflex. Some examples of 5-HT₃ receptor antagonists used for nausea include ondansetron, granisetron, and palonosetron. B, C, and D are not correct choices because 5-HT₃ receptor antagonists are not typically used for somnolence, REMS sleep disorder, or GERD.

Question 3

Common eicosanoids include:&#10;A) thromboxanes.&#10;B) leukotrienes.&#10;C) hydroperoxyeicosatrienoic acids.&#10;D) all of the above.

Accepted Answer

All of the given options, thromboxanes, leukotrienes, and hydroperoxyeicosatrienoic acids, are common eicosanoids. Eicosanoids are signaling molecules derived from polyunsaturated fatty acids and they play an important role in inflammation, pain, and other physiological processes. Thromboxanes are involved in platelet aggregation and blood clot formation, leukotrienes are involved in asthma and allergic reactions, and hydroperoxyeicosatrienoic acids are involved in vascular and immune responses.

Question 4

Prostaglandin analogues have been used for:&#10;A) termination of pregnancy.&#10;B) glaucoma.&#10;C) treatment of impotence.&#10;D) all of the above.

Accepted Answer

Prostaglandin analogues have diverse medical applications, including the termination of pregnancy, treatment of glaucoma by reducing intraocular pressure, and in some cases, treatment of erectile dysfunction, making all of the provided options correct.

Deck 30: Prostaglandins and Serotonin