Question 1

Which of the follow is standard therapy in non-myeloid anaemia?&#10;A) Ferrous sulfate&#10;B) Folic acid&#10;C) Erythropoietin&#10;D) Parenteral B12

Accepted Answer

Erythropoietin is a standard therapy in non-myeloid anemia as it stimulates the production of red blood cells. Ferrous sulfate and folic acid may be used as supplements to address iron or folate deficiencies, but they are not always necessary or appropriate. Parenteral B₁₂ is not a known medication or treatment for anemia.

Question 2

An important consideration associated with anaemias caused by vitamin B12 deficiency is that:&#10;A) high doses of vitamin B?? can induce hyperkalaemia.&#10;B) in pernicious anaemia, vitamin B?? must be administered parenterally.&#10;C) the clinical form of vitamin B?? is called pyridoxine.&#10;D) solutions of vitamin B?? must be kept refrigerated.

Accepted Answer

Pernicious anaemia is caused by a deficiency in vitamin B12, which is necessary for red blood cell production. This type of anaemia requires vitamin B12 to be administered parenterally (intramuscularly or subcutaneously) as oral supplements are not effective. High doses of vitamin B12 do not induce hyperkalaemia. Pyridoxine is the clinical form of vitamin B6, not vitamin B12. There is no requirement to keep solutions of vitamin B12 refrigerated.

Question 3

Which one of the following is considered a cause of anaemia?&#10;A) Vitamin D? deficiency&#10;B) Exposure to anabolic steroids&#10;C) Chronic renal failure&#10;D) Elemental iron overload

Accepted Answer

Chronic renal failure can cause anaemia by affecting the production of the hormone erythropoietin, which is important for the production of red blood cells.

Question 4

To reduce the gastric irritation associated with oral iron therapy,the person should be advised to take the preparation:&#10;A) as a suppository.&#10;B) with or immediately after meals.&#10;C) at bedtime.&#10;D) with an antacid.

Accepted Answer

Taking oral iron preparations with or immediately after meals can help reduce gastric irritation by allowing the medication to mix with food and be slowly absorbed in the digestive tract. Taking the medication at bedtime may interfere with sleep or cause discomfort. Using a suppository would not be appropriate for oral iron therapy, and while taking an antacid may help reduce gastric irritation, it may also decrease the absorption of the iron.

Question 5

The form of erythropoietin for clinical use:&#10;A) may induce a hypertensive state during therapy.&#10;B) is extracted from human urine.&#10;C) induces a rise in haemoglobin levels within two days of starting therapy.&#10;D) contains iron supplements in order to facilitate haemoglobin production.

Accepted Answer

Erythropoietin used in clinical settings can indeed cause hypertension as a side effect. This is because it stimulates the production of red blood cells, which can increase blood viscosity and in turn, raise blood pressure.

Question 6

Treatment with iron supplementation is usually continued for about ________ to ensure replenishment of iron stores in iron deficiency anaemia.&#10;A) two weeks&#10;B) one month&#10;C) two months&#10;D) three months

Accepted Answer

Treatment with iron supplementation for iron deficiency anemia is typically continued for about three months to ensure full replenishment of iron stores, even after the normalization of hemoglobin levels.

Question 7

High doses of vitamin B?? may cause&#10;A) hypotension.&#10;B) hypokalaemia.&#10;C) constipation.&#10;D) folate deficiency.

Accepted Answer

High doses of vitamin B12 can lead to hypokalaemia (low potassium levels) due to increased red blood cell production, which can deplete potassium.

Question 8

The absorption of iron in the gut may be enhanced by :&#10;A) vitamin A.&#10;B) vitamin E.&#10;C) vitamin C.&#10;D) folate.

Accepted Answer

Vitamin C is known to enhance the absorption of non-heme iron, which is the form of iron found in plant-based sources and iron-fortified foods. Vitamin A, vitamin E, and folate do not have a significant impact on iron absorption.

Question 9

Which food is a natural source of folic acid?&#10;A) Brussel sprouts&#10;B) Chocolate&#10;C) Limes&#10;D) Barley

Accepted Answer

Brussel sprouts are a natural source of folic acid. Folic acid is also known as vitamin B9 or folate. It is an essential nutrient that supports many bodily functions, including cell growth and reproduction. Adequate intake of folic acid is especially important for pregnant women, as it helps prevent birth defects in the baby's brain and spine. Brussel sprouts are also rich in other nutrients, such as vitamin C, vitamin K, and fiber.

Deck 52: Antianaemic Agents