Deck 77: Medicines Used in Diseases of the Skin

Question 1

Psoriasis is thought to involve:

A) an inflammatory response involving T cell activation.
B) an allergic reaction where skin mast cells degranulate.
C) immune complexes lodging in the skin and triggering a hypersensitivity reaction.
D) a viral infection of the skin and adjacent mucous membranes.

Answer 1

an inflammatory response involving T cell activation.

Question 2

Useful drugs in the management of baldness are those that:

A) act as oestrogen receptor antagonists.
B) stimulate the release of luteinising hormone.
C) inhibit the metabolism of testosterone.
D) have progestogenic activity.

Answer 2

inhibit the metabolism of testosterone.

Question 3

Children with eczema are more likely to develop:

A) skin cancer.
B) asthma.
C) verrucae.
D) alopecia.

Answer 3

asthma.

Question 4

Which one of the following sunscreens blocks almost 97 per cent of UVB light?

A) SPF 6
B) SPF 15
C) SPF 30
D) SPF 50

Question 5

How many applications of podophyllum are usually require to remove a wart?

A) One
B) Two
C) Three
D) Four

Question 6

Which non-drug product is considered the mainstay of eczema treatment?

A) Colloidal oatmeal
B) Coal tar
C) Emollients
D) Baking soda

Question 7

Botulinum toxin is indicated in the treatment of which skin disorder?

A) Hyperhidrosis
B) Rosacea
C) Eczema
D) Psoriasis

Question 8

Dandruff can be caused in part by a fungal infection.

Question 9

The mechanism of action of the counterirritant capsaicin is thought to involve:

A) vasoconstriction of skin blood vessels.
B) a stimulation of opioid receptors.
C) an interference in the release of substance P.
D) a softening and loosening of the outer layers of the skin.

Question 10

Acne rosacea is best treated with topical:

A) erythromycin.
B) clindamycin.
C) metronidazole.
D) clotrimazole.

Question 11

Which of the following statements about the skin are true? Select all that apply.

A) It has three main layers.
B) The subcutaneous layer is the second layer.
C) It is the largest organ.
D) It helps regulate body temperature.
E) Melanocytes in the skin cause pigmentation.

Question 12

When using the vitamin D analogue calcipotriol for psoriasis,it can be carefully applied to lesions located on the:

A) scalp.
B) face.
C) body surface.
D) skin folds.

Question 13

For the treatment of scabies with crotamiton,application is required ________ until eradicated.

A) hourly
B) daily
C) twice weekly
D) weekly

Question 14

The epidermal layer that is also known as the grainy layer is called the stratum:

A) basale.
B) granulosum.
C) corneum.
D) spinosum.

Question 15

One of the newer treatments for psoriasis is:

A) coal tar.
B) UV light treatment.
C) methotrexate.
D) ustekinumab.

Question 16

Which topical preparation would be most difficult to completely absorb?

A) Gel
B) Lotion
C) Cream
D) Ointment

Question 17

Nappy rash can occur due to:

A) the use of disposable nappy products.
B) the production of ammonia from the breakdown of urine.
C) hypersensitivity reactions to breast milk.
D) all of the above.

Question 18

Which drug is absolutely prohibited in pregnancy?

A) Tetracycline
B) Azelaic acid
C) Metronidazole
D) Isotretinoin

Question 19

Women of childbearing age should take which precaution with isotretinoin treatment?

A) Avoid sunscreen use.
B) Monitor iron levels.
C) Supplement with folate.
D) Ensure adequate contraception.

Question 20

SPF 15 sunscreens block about:

A) 94 per cent of UVB light, and allow for 6 per cent penetration.
B) 95 per cent of UVB light, and allow for 5 per cent penetration.
C) 96 per cent of UVB light, and allow for 4 per cent penetration.
D) 97 per cent of UVB light, and allow for 3 per cent penetration.

Question 21

Discuss the effects of UV rays on the skin.