Deck 17: Adaptive Immunity: Specific Defenses of the Host

Question 1

Which of the following is not a characteristic of cellular immunity?

A) Cells are processed in the thymus gland.
B) It can inhibit the immune response.
C) The cells originate in bone marrow.
D) It includes macrophages.
E) None of the above.

Answer 1

D

Question 2

Patients with an inherited type of colon cancer called familial adenomatous polyposis have a mutation in the gene that codes for

A) IgE antibodies.
B) Helper T cells.
C) Phagocytosis.
D) Apoptosis.
E) ADCC.

Answer 2

D

Question 3

Type of immunity resulting from transfer of antibodies from one individual to a susceptible individual by means of injection.

A) Innate immunity
B) Naturally acquired active immunity
C) Naturally acquired passive immunity
D) Artificially acquired active immunity
E) Artificially acquired passive immunity

Answer 3

E

Question 4

Which statement is incorrect?

A) The constant region of a heavy chain is the same for all antibodies.
B) The Fc region attaches to a host cell.
C) The variable region of a heavy chain binds with antigen.
D) The variable region of a light chain binds with antigen.
E) None of the above.

Question 5

Which of the following destroys virus- infected cells?

A) TR
B) Dendritic cells
C) TC
D) TH
E) None of the above

Question 6

All of the following are true about natural killer cells except

A) They are stimulated by an antigen.
B) They destroy tumor cells.
C) They destroy virus- infected cells.
D) They destroy cells lacking MHC I.
E) None of the above.

Question 7

The antibodies found in mucus, saliva, and tears are

A) IgG.
B) IgM.
C) IgA.
D) IgD.
E) IgE.

Question 8

In addition to IgG, the antibodies that can fix complement are

A) IgG.
B) IgM.
C) IgA.
D) IgD.
E) IgE.

Question 9

Chemical signals sent between leukocytes are

A) Colony- stimulating factor.
B) TCRs
C) Tumor necrosis factor.
D) Interferons.
E) Interleukins.

Question 10

Immunity due to injection of an antigen.

A) Innate immunity
B) Naturally acquired active immunity
C) Naturally acquired passive immunity
D) Artificially acquired active immunity
E) Artificially acquired passive immunity

Question 11

IL- 2, produced by TH cells,

A) Stimulates TH cell maturation.
B) Activates antigen- presenting cells.
C) Causes phagocytosis.
D) Activates macrophages.
E) None of the above.

Question 12

Large antibodies that agglutinate antigens are

A) IgG.
B) IgM.
C) IgA.
D) IgD.
E) IgE.

Question 13

T cells are activated by:

A) Complement.
B) Cytokines released by B cells.
C) Cytokines released by dentritic cells.
D) Interaction between TCRs and MHC II.
E) Interaction between CD4 and MHC II.

Question 14

Figure 17.2

In Figure 17.2, which areas represent antigen- binding sites?

A) a and b
B) a and c
C) b and c
D) c and d
E) b and d

Question 15

Figure 17.1

In Figure 17.1, which letter on the graph indicates the patient's response to a second antigen?

A) a
B) b
C) c
D) d
E) e

Question 16

Which one of the following causes transmembrane channels in target cells?

A) IL- 1
B) Antigen
C) Perforin
D) Hapten
E) IL- 2

Question 17

The best definition of an antigen is

A) Something foreign in the body.
B) A chemical that combines with antibodies.
C) A chemical that elicits an antibody response and can combine with these antibodies.
D) A protein that combines with antibodies.
E) A pathogen.

Question 18

Newborns' immunity due to the transfer of antibodies across the placenta.

A) Innate immunity
B) Naturally acquired active immunity
C) Naturally acquired passive immunity
D) Artificially acquired active immunity
E) Artificially acquired passive immunity

Question 19

Cytokines released by TH1 cells:

A) Kill parasites.
B) Convert B cells to T cells.
C) Convert TH2cells to TH1 cells.
D) Convert TH1 cells to TH2 cells.
E) Activate CD8 cells to CTLs.

Question 20

Figure 17.2

In Figure 17.2, which areas are similar for all IgG antibodies?

A) a and b
B) a and c
C) b and c
D) c and d
E) b and d

Question 21

Antigens coated with antibodies are susceptible to

A) B cells.
B) Phagocytosis.
C) Helper T cells.
D) Further antibody attack.
E) None of the above.

Question 22

Figure 17.2

In Figure 17.2, which areas are different for all IgM antibodies?

A) a and b
B) a and c
C) b and c
D) c and d

Question 23

The most abundant class of antibodies in serum is

A) IgG.
B) IgM.
C) IgA.
D) IgD.
E) IgE.

Question 24

Antigen- antibody binding may result in all of the following except

A) Complement activation.
B) Agglutination of the antigens.
C) IL- 2 production.
D) Neutralization of the antigen.
E) Opsonization of the antigen.

Question 25

The antibodies that can bind to large parasites are

A) IgG.
B) IgM.
C) IgA.
D) IgD.
E) IgE.

Question 26

Cell death caused by perforin and granzymes is caused by

A) TH₂ cells.
B) TH1 cells.
C) CD8 cells.
D) Cytotoxic T lymphocytes.
E) B cells.

Question 27

Immunity resulting from recovery from mumps.

A) Innate immunity
B) Naturally acquired active immunity
C) Naturally acquired passive immunity
D) Artificially acquired active immunity
E) Artificially acquired passive immunity

Question 28

The specificity of an antibody is due to

A) Its valence.
B) The constant portions of the H and L chains.
C) The variable portions of the H and L chains.
D) The L chains.
E) The H chains.

Question 29

Immunity due to injection of tetanus toxoid.

A) Innate immunity
B) Naturally acquired active immunity
C) Naturally acquired passive immunity
D) Artificially acquired active immunity
E) Artificially acquired passive immunity

Question 30

An antibody's Fc region can be bound by

A) Macrophages.
B) B cells.
C) Helper T cells.
D) Antibodies.
E) None of the above.

Question 31

Plasma cells are activated by a(n)

A) T cell.
B) Memory cell.
C) Antigen.
D) B cell.
E) None of the above.

Question 32

Figure 17.1

In Figure 17.1, the arrow at time d indicates

A) The secondary response.
B) The time of exposure to the same antigen as at time a.
C) Exposure to a new antigen.
D) The primary response.
E) None of the above.

Question 33

Which of the following is not a characteristic of B cells?

A) They have antibodies on their surfaces.
B) They recognize antigens associated with MHC I.
C) They are responsible for antibody formation.
D) They originate in bone marrow.
E) They are responsible for the memory response.

Question 34

Type of immunity resulting from vaccination.

A) Innate immunity
B) Naturally acquired active immunity
C) Naturally acquired passive immunity
D) Artificially acquired active immunity
E) Artificially acquired passive immunity

Question 35

The presence of which of the following indicates a current infection rather than a previous infection or vaccination?

A) IgG
B) IgA
C) IgD
D) IgE
E) IgM

Question 36

The best definition of an antibody is

A) A protein that inactivates or kills an antigen.
B) An immunoglobulin.
C) A protein made in response to an antigen that can combine with that antigen.
D) A serum protein.
E) None of the above.

Question 37

The following events elicit an antibody response. What is the third step?

A) APC phagocytizes antigen.
B) TH cell produces cytokines.
C) B cell is activated.
D) Antigen- digest goes to surface of APC.
E) TH cell recognizes antigen- digest and MHC II.

Question 38

The antibodies found on B cells are

A) IgG.
B) IgM.
C) IgA.
D) IgD.
E) IgE.

Question 39

Immunity that is not due to antibodies.

A) Innate immunity
B) Naturally acquired active immunity
C) Naturally acquired passive immunity
D) Artificially acquired active immunity
E) Artificially acquired passive immunity

Question 40

Which of the following recognizes antigens displayed on host cells with MHC II?

A) TH cell
B) Natural killer cell
C) Basophil
D) B cell
E) TC cell

Question 41

A human's resistance to canine distemper.

A) Innate immunity
B) Naturally acquired active immunity
C) Naturally acquired passive immunity
D) Artificially acquired active immunity
E) Artificially acquired passive immunity

Question 42

The following events occur in cellular immunity. What is the third step?

A) Antigen enters M cell
B) TH cells proliferate.
C) Antibodies are produced.
D) Dendritic cell takes up antigen.
E) TH cell produces cytokines.