Deck 2: Psychopharmacology for Mental Health, Part B

Question 1

The biggest problem with tyramine intolerance is

A)NE release and its consequences
B)GABA release and hypertensive crisis
C)Not being able to drink beer
D)5-HT agonism and increased aggression

Answer 1

NE release and its consequences

Question 2

Which of the following is not a mechanism of action for psychotropic medications?

A)Effects on 2^nd messengers
B)Effects on transporter molecules
C)Preventing the release of neurotransmitter
D)Creating new functions in a cell

Answer 2

Creating new functions in a cell

Question 3

The key mechanism of action in all families of benzodiazepines is

A)GABA antagonism
B)NE agonism
C)GABA agonism
D)DA antagonism

Answer 3

GABA agonism

Question 4

When enzymes that are responsible for drug metabolism increase in response to the consistent presence of the drug, we call that

A)metabolic tolerance
B)cross-tolerance
C)cellular tolerance
D)antagonism
E)The Michigan Rag

Question 5

In your drawing in part I, the antidepressant sertraline would likely

A)Act as a 5-HT antagonist
B)Facilitate reuptake of NE
C)Inhibit the extra-cellular transporter molecule
D)Inhibit the extra-cellular enzyme

Question 6

An example of cross tolerance is the relationship between

A)SSRI and Tricyclic antidepressants
B)MAO Inhibitors and SSRIs
C)Benzodiazepines and alcohol
D)Stimulants and dopamine antagonists

Question 7

The primary mechanism of therapeutic action for Abilify is

A)DA agonism, 5-HT antagonism
B)DA and 5-HT agonism
C)DA and NE antagonism
D)We really don't know

Question 8

A loading dose refers to

A)an initial dose that is lower than subsequent doses
B)an initial dose that is higher than subsequent doses
C)an initial dose that is quickly titrated up
D)an initial dose that is the same as the maintenance dose

Question 9

The best benzodiazepine for elderly patients would be one less reliant on the liver for metabolizing like

A)alprazolam
B)oxazepam
C)diazepam
D)chlordiazepoxide

Question 10

In your drawing from part 1, a synaptic cleft is

A)a physical gap across which neurotransmitters diffuse
B)the transmitting element of a neuron
C)the receiving element of a neuron
D)a membrane-bound package of neurotransmitter molecules

Question 11

Which of the following is not a vegetative symptom of depression?

A)pronounced anhedonia
B)sleep disruption
C)decreased sex drive
D)low self-esteem

Question 12

Stimulating an autoreceptor will

A)result in seizure
B)result in more neurotransmitter in the cleft
C)result in less neurotransmitter in the cleft
D)result in DA inhibition only
E)result in a disruption of the Laffer curve

Question 13

The black box warning on SSRI antidepressants means
a.these medications should never be given to children
b.these medications are dangerous in vulnerable populations
c.these medications should only be given under special circumstances
d.these medications lack efficacy for the groups indicated.

Question 14

A specialized chemical messenger that carries information from one neuron to another at the synapse is good definition of

A)monoamine oxidase
B)acetylcholinesterase
C)a receptor molecule
D)a neurotransmitter molecule

Question 15

Although Olanzapine is known as a new-generation anti-psychotic, it may also be used as

A)An anti-manic agent
B)An antiparkinsonian tx
C)An antidepressant
D)An antebellum drug

Question 16

The second messenger systems sequence of events moves in which order?

A)enzyme, receptor, first messenger, G-protein
B)G-protein, first messenger, receptor, enzyme
C)First messenger, G-protein, enzyme
D)First messenger, enzyme, receptor

Question 17

The efficacy of Buspirone for anxiety is

A)Exactly the same as antidepressant efficacy
B)Approximately 55%
C)Close to 90%
D)Better than alprazolam

Question 18

The blood-brain barrier

A)is inconsequential where meds are concerned
B)was discovered by Bill Glazer in 1950
C)is a lipophilicitious membrane psychotropic meds must pass through
D)is a highly permeable membrane that medications pass through

Question 19

Advocating for clients

A)is not within the ethical practice of either psychology or counseling
B)is particularly important with children
C)is usually done by psychiatrists
D)is the province of social workers and case managers.

Question 20

Of two families of benzodiazepine receptors
a.Both must be targeted for anxiolytic action
b.Both disrupt REM sleep when stimulated
c.Only one needs to be targeted to create a hypnotic
d.Both are operative in BuSpar

Question 21

the most successful non-barbiturate alternative seems to have been

A)Meprobamate
B)Ambien
C)Benzodiazepines
D)Lunestra

Question 22

You are consulting on a case of an 11-year-old with social anxiety disorder. His mother is upset because she was told by a friend her son would be on medication the rest of his life. What do you ?

Question 23

Of the following benzodiazepines, the one with the longest half-life would be

A)Serax
B)Xanax
C)Librium
D)Alprazolam

Question 24

Describe the theory of how antidepressants work describing at least 4 steps in the mechanism of action. What are the important ramifications of this theory for clients' lifestyle and the importance of counseling

Question 25

What is Melody Petersen's position on Direct-to-Consumer advertising? Do you agree or disagree and why?

Question 26

What are some of Melody Petersen's recommendations for decreasing the influence of pharmaceutical companies? Do you agree or disagree and why?

Question 27

A potentially dangerous side effect of lithium is
a.EPS
b.disrupted QTc interval
c.when a high therapeutic dose becomes a toxic dose
d.jaundice

Question 28

Lithium
a.can be effective in treating Bipolar I Disorder but requires blood monitoring
b.can be effective in treating premeditated aggression in prisons
c.can be effective in treating hyper somnolence
d.can be effective as an additive to soda

Question 29

Janice is a 23-year-old Asian-American female recently diagnosed with Major Depressive Disorder Single Episode) and put on duloxetine. She asks you what the meds should do and what side effects there are. How do you respond?

Question 30

How has the chemical imbalance theory of mental illness been falsified?

Question 31

Your client is currently taking MAO Inhibitors for tx-resistant depression. He calls in a panic because he forgot about his dietary restrictions and just ate a pint of cottage cheese. What do you advise him to do?

Question 32

The benefits of buspirone over benzodiazepines include

A)its efficacy
B)its non-addictive properties
C)onset of action
D)neurotransmitters targeted

Question 33

For children with severe depression
a.they should only get tricyclic antidepressants
b.they should only get SSRIs and be closely monitored
c.there is never a case when antidepressants are appropriate for kids
d.the amount of side effects drive which class of drugs to use
SHORT

Question 34

What are 3 important differences between Benzodiazapines and buspirone?

Question 35

For an older client age 75) we would expect prescribers to

A)start with a loading dose
B)start with a maintenance dose
C)start with a low dose to check response
D)start with the minimum therapeutic dose.

Question 36

The cellular/molecular theory of antidepressant action
a.helps us make logical links between what meds do and lifestyle choices
b.helps us make logical links between what meds do and etiology of depression
c.helps us advocate for clients because it implies a chemical imbalance.
d.reminds us that most theories build on their predecessors

Question 37

One problem with pediatric diagnosis of Bipolar I Disorder is
a.the criteria are not normed on this population
b.the criteria for depression are unreliable
c.the criteria for rapid cycling are never met
d.the criteria for mixed episode are never met