Deck 58: Pancreatic and Biliary Secretion

Question 1

Contraction of the gallbladder is caused mainly by

A) CCK
B) So m ato sta tin
C) G as trin
D) Se cr etin
E) M otilin

Answer 1

A

Question 2

Which of the following is NOT a proteolytic secretion of the pancreas?

A) T ryp sin
B) C hym otr yps in
C) Elastase
D) Pe ps in
E) Carboxypeptidase

Answer 2

D

Question 3

Which of the following is NOT a component of bile?

A) M uc in
B) Cholesterol
C) Phospholipids
D) Bile acids
E) Co-lipase

Answer 3

E

Question 4

The sphincter of Oddi

A) Regulates flow of bile from liver to gallbladder
B) Controls flow of bile into the pancreas
C) Regulates the flow of bile and pancreatic juice into the small intestine
D) Regulates intestinal secretion from the Crypts of Lieberkuhn
E) Regulates flow from ileum to cecum

Question 5

The pancreas secretes all of the following lipolytic enzymes EXCEPT

A) Cholesterol hydrolase
B) Pancreatic co-lipase
C) Phospholipase A2
D) Pancreatic lipase
E) Phospholipase C

Question 6

Enzyme secretion by the pancreas is stimulated by

A) CC K ac ting on pan cre atic du ctal ce lls via vag al affe rents
B) CC K acting on p ancrea tic acinar cells via vag al afferents
C) Se cr etin ac ting on pa nc re atic du cta l ce lls
D) Se cr etin ac ting on pa nc re atic ac ina r c ells
E) SS T ac ting on pa nc re atic ac ina r c ells

Question 7

Pr ote olys is in the pa nc re as is p re ve nte d b y

A) Sec retion of pro teolytic e nzym es in in active prec urso r form
B) Encasing the enzymes in liposomes
C) Tryp sin inh ibitor
D) Com petitive inhibition
E) A and C are correct

Question 8

The m ain fun ctio n o f bile ac ids is d ue to th eir

A) Solub ilizing ac tion on fats and fat d igestion p rodu cts
B) Enterohepatic circulation
C) Activation of phospholipase A2
D) Content of cholesterol
E) Hydrolysis of triglycerides

Question 9

Secon dary bile acids are

A) Mad e by bacteria in the intestines
B) Made by hepatocytes from cholesterol
C) Absorbed in the terminal ileum
D) Absorbed along with micelles
E) Both A and C are correct

Question 10

The m ajo r s tim ulu s f or se cr etin se cr etio n is

A) Mechanical irritation of the duodenum
B) H + in the duodenal lumen
C) Distension of the duodenum
D) Am ino acids in the duodenum
E) Fat digestion products in the duodenum

Question 11

The pancreatic proteolytic enzymes do not digest the pancreas because

A) They are s ecrete d in ina ctive p recu rsor fo rm
B) The zymogen granules protect the cell by compartmentalization
C) Trypsin inhibitor prevents premature activation of the enzymes
D) There are no substrates for the enzymes in the pancreas Both A and C are correct

Question 12

The funct ion of HCO - in pan cre atic juic e is to

A) Neutralize stomach H+ sec rete d b y pa rietal c ells
B) Neutralize blood HCO - produced by the stomach
C) Balance PCO₂ in the gut
D) Activate proteolytic enzymes
E) D en atu re pro tein s in the ch ym e

Question 13

The gallbladder

A) Sto res a nd con cen trate s bile
B) Mainly stores toxic materials prior to their excretion
C) C on tra cts in re sp on se to s ec re tin
D) C on tra cts in re sp on se to g as trin
E) Converts primary bile acids to secondary bile acids

Question 14

CFT R stands for

A) Cholecystokinin free transfer receptor
B) Cholesterol free transport receptor
C) Chloride free transport receptor
D) Cystic fibrosis transmembrane conductance regulator
E) Chloride free transport regulator

Question 15

The transporter that drives pancreatic secretion is the

A) CFTR on the apical membrane - -
B) HCO 3 -Cl exchanger on the apical membrane
C) Carbonic anhydrase
D) Na+-K+-ATPase on the apical membrane
E) Na+-H + exchanger on the basolateral membrane

Question 16

A HCO - -rich secretion by bile duct and pancreas is stimulated by

A) CCK
B) So m ato sta tin
C) G as trin
D) Se cret in
E) M otilin

Question 17

The primary bile salts include

A) C ho lic a cid an d d eo xyc ho lic a cid
B) Lith oc ho lic a cid an d c he no de ox ych olic ac id
C) U rs od eo xyc ho lic a cid an d c ho lic a cid
D) Lith oc ho lic a cid an d c ho lic a cid
E) Ch olic a cid a nd che no de ox ych olic a cid

Question 18

The on ly pa nc re atic se cr etio n th at d ige sts sta rc h is

A) Elastase
B) Isomaltase
C) Amylase
D) Cellulase
E) Sucrase

Question 19

Bile is produced by

A) Hepatocytes
B) Pa nc re atic ac ina r c ells
C) Pa nc re atic du cta l ce lls
D) Enterocytes
E) The gallbladder

Question 20

CCK

A) Is a glyc op ro tein
B) Stimulates stomach H Cl secretion
C) Stimulates CFTR
D) Stimulates gall bladder contraction
E) Inhibits secretin action

Question 21

Which state m ent a bou t prim ary bile ac ids is N OT true?

A) Primary bile acids undergo enterohepatic circulation
B) Primary bile acids are conjugated with taurine
C) Primary bile acids are conjugated with glycine
D) Primary bile acids are absorbed in the terminal ileum
E) Primary bile acids are excreted by hepatocytes into the portal blood

Question 22

O ne of t he m os t po ten t stim uli fo r he pa tic b ile s ec re tion is

A) Uptake of bile acids from the portal blood
B) CCK
C) Se cr etin
D) Parasympathetic nerves
E) Sympathetic nerves

Question 23

The duct leading to the gallbladder is called the

A) Hepatic bile duct
B) Com mon bile duct
C) Cystic duct
D) Pancreatic bile duct
E) Biliary tree