Deck 58: Pharmacotherapy of Neoplasia

Question 1

Alkylating agents kill cancer cells by:
1)Disrupting critical cellular pathways of cancer cells.
2)Changing the shape of the DNA double helix and preventing DNA from duplicating during cell division.
3)Blocking substances necessary for continued growth of tumors.
4)Containing substances from bacteria that can kill cancer cells.

Answer 1

2

Question 2

All of the following are true of hormone antagonists except:
1)They produce more debilitating adverse effects than do other antineoplastics.
2)They are not cytotoxic, so they rarely produce cancer cures when used alone.
3)They block substances essential for hormone growth.
4)They produce few debilitating adverse effects that other antineoplastics produce.

Answer 2

4

Question 3

All of the following are true about biological response modifiers except:
1)They alter the body's defense system to enhance removal of the foreign cancer cell.
2)Some are immunostimulants, and, when given with other antineoplastic agents, help limit severe myelosuppression.
3)They are used to prevent transplant rejections.
4)They are more toxic than are most classes of antineoplastics.

Answer 3

2

Question 4

If the nurse notices blood lab tests have dropped below normal, the best initial action would be to:
1)Tell the patient to stop the drug for three days to give the body some time for the levels to rise back to normal.
2)Tell the patient to take the drug every other day for a few weeks.
3)Tell the patient to stop the drug and notify her health care provider.
4)Tell the patient to take her normal dose that day, but come in for some lab work.

Question 5

What action best describes how the antimetabolites kill cancer cells?
1)They change the shape of the DNA and prevent division of cancer cells.
2)They disrupt metabolic pathways, slowing growth of cancer cells.
3)They contain bacterial substances that can kill cancer cells.
4)They use the body's immune system to kill tumor cells.

Question 6

Agents with antineoplastic activity that have been isolated from a number of plants work in what way?
1)They aid in attachment to the receptor sites on the cancer cell.
2)They contain substances that have the ability to kill the cancer cells.
3)They arrest cell division, or mitosis.
4)They prevent conversion from DNA to RNA.

Question 7

Many chemotherapy agents cause nausea and vomiting.The type and dose of antiemetic prescribed are based upon:
1)The severity of the patient's symptoms.
2)The potential of specific antineoplastics to cause nausea and vomiting.
3)The dose of the antineoplastics.
4)How many other medications the patient is taking.

Question 8

Antibiotic antineoplastics work by what mechanism?
1)They contain substances from viruses that have the ability to kill cancer cells.
2)They contain substances from plants that have the ability to kill cancer cells.
3)They contain substances from hormones that have the ability to kill cancer cells.
4)They contain substances from bacteria that have the ability to kill cancer cells.

Question 9

The nurse who has received special training to administer chemotherapy is called:
1)A chemotherapy nurse.
2)An antineoplastic administrator.
3)An oncology nurse.
4)An IV therapy nurse.

Question 10

A main common theme among all the antineoplastic agents is:
1)Their mechanism of action.
2)Their toxicity-their ability to kill cancer cell.
3)Their drug interactions.
4)Their side effects.

Question 11

Bone marrow toxicity does not suppress what type of cells?
1)T cells
2)White blood cells
3)Red blood cells
4)Platelets