Deck 55: Pharmacotherapy of Non-Hiv Viral Infections

Question 1

It is crucial to monitor which of the following laboratory tests when a client is taking acyclovir (Zovirax)?
1)Blood urea nitrogen (BUN), creatinine, and complete blood count (CBC)
2)White blood count (WBC)and aspartate aminotransferase (AST)
3)Viral culture and urinalysis
4)Fasting and postprandial blood sugars

Answer 1

2

Question 2

The nurse caring for which of the following clients would question an order for acyclovir (Zovirax)?
1)Client with cytomegalovirus
2)Client with varicella-zoster
3)Client with hepatitis B
4)Client with herpes simplex 2 encephalitis

Answer 2

3

Question 3

A client telephones a nurse, reporting fatigue since starting ribavirin therapy four months ago.The client also mentions that in the last week, he has developed shortness of breath, which has been worsening.What should the nurse tell the patient?
1)"You should come into the office to have some blood work drawn for possible hemolytic anemia."
2)"This is a normal adverse effect of this medication.Take it easy, and your symptoms will resolve."
3)"These symptoms could be signs of an allergy to the medication.Take an antihistamine and see if you notice improvement."
4)"Stop taking the medication.Your physician will try another medication for hepatitis treatment."

Answer 3

1

Question 4

The physician orders amantadine (Symmetrel)for a client with influenza.Which part of the client's health history would the nurse report to the physician prior to administering amantadine (Symmetrel)?
1)Allergy to shellfish
2)Diabetes mellitus
3)Chronic obstructive pulmonary disease (COPD)
4)Epilepsy

Question 5

A nurse would know that the intervention of education with a patient taking ganciclovir was effective when the patient states:
1)"I can stop taking the mediation when my symptoms are gone."
2)"I need to tell my doctor when I have flu-like symptoms."
3)"I can take this medication on an empty stomach."
4)"This medication is OK to take in pregnancy."

Question 6

The nurse is aware that to achieve the most therapeutic effects, the best time to administer oseltamivir (Tamiflu)or zanamivir (Relenza)is:
1)At the same time as the vaccine.
2)As soon as the client has been exposed to someone with influenza.
3)Within 48 hours of the onset of symptoms.
4)Anytime during the course of the illness.

Question 7

Which statement is accurate regarding non-HIV antiviral drugs?
1)New research on antivirals has proven more effective than have the results of research with antibacterials.
2)Antivirals have a narrow spectrum of coverage.
3)Antivirals have fewer side effects than antibiotics.
4)Antivirals decrease the effects of the host cell's biological processes.

Question 8

Why is a virus known as an intracellular parasite?
1)The virus affects only one species of living organism.
2)The virus contains DNA or RNA, but not necessarily both.
3)The virus is surrounded by a protein coat called a capsid.
4)The virus is incapable of causing infection unless it has invaded a host cell.

Question 9

Antiviral pharmacotherapy is extremely challenging because:
1)High doses of medication are required to achieve therapeutic effects.
2)Rapid mutation of viruses quickly makes drugs ineffective.
3)Their broad spectrum causes severe adverse effects.
4)The drug scheduling makes compliance difficult.

Question 10

The role of the capsid in the viral structure includes:
1)Facilitating viral replication involving RNA and DNA.
2)Triggering body defenses to remove the invader.
3)Helping the virus attach to the cell membrane of the host.
4)Allowing for release of the viral infection from the host.

Question 11

The synthesis stage of viral replication for viruses includes:
1)The virus replicates by making viral capsid proteins and enzymes.
2)The virus lives dormant in the environment for months to years.
3)The cell bursts, releasing viral particles throughout the host.
4)The virus penetrates the host cell in order to "inject" its genetic material into the host.

Question 12

A client wants to be vaccinated against viral hepatitis.The nurse would inform the client that a vaccine available is for:
1)Hepatitis B only.
2)Hepatitis A (HAV)and B (HAB).
3)Hepatitis B and C.
4)Hepatitis non-A non-B.

Question 13

The client receives acyclovir (Zovirax)for treatment of genital herpes.What is a priority assessment by the nurse?
1)Respiratory distress
2)Thrombocytopenia
3)Increased serum creatinine
4)Auditory and visual hallucinations

Question 14

In addition to health care workers, what other groups should receive the hepatitis B (HBV)vaccine?
1)Residents of long-term care facilities
2)Persons with chronic cardiopulmonary disease
3)Healthy adults older than 50 years
4)Infants and children

Question 15

Lamivudine targets which stage in the pathogenesis of a viral infection?
1)Inhibiting viral replication
2)Inhibiting penetration of the viral material
3)Inhibiting attachment at the receptor site
4)Inhibiting release of the virus