Question 1

Besides cystic fibrosis, which other medical state may trigger the need for pancreatic enzymes?&#10;A)Paget's disease&#10;B)Pulmonary cancers&#10;C)Gallbladder surgery&#10;D)Some bariatric surgeries&#10;

Accepted Answer

Some bariatric surgeries can lead to malabsorption issues, necessitating the use of pancreatic enzymes to aid digestion.

Question 2

Potentially fatal granulocytopenia has been associated with treatment of hyperthyroidism with propylthiouracil. Patients should be taught to report:&#10;A)Tinnitus and decreased salivation&#10;B)Fever and sore throat&#10;C)Hypocalcemia and osteoporosis&#10;D)Laryngeal edema and difficulty swallowing&#10;

Accepted Answer

Granulocytopenia, a significant decrease in neutrophil count, increases the risk of infection. Fever and sore throat are common signs of infection, which patients taking propylthiouracil should promptly report as they could indicate potentially life-threatening complications.

Question 3

Which of the following is not an indication that growth hormone supplements should be discontinued?&#10;A)Imaging indication of epiphyseal closure&#10;B)Growth curve increases that have plateaued&#10;C)Complaints of mild bone pain&#10;D)Achievement of anticipated height goals&#10;

Accepted Answer

Growth hormone supplements are typically discontinued for reasons such as epiphyseal closure (A), plateauing of growth curves (B), and achievement of height goals (D). Mild bone pain (C) is not usually a reason to discontinue growth hormone therapy, as it can be a common side effect and may not indicate a serious problem.

Question 4

Which of the following statements about pancreatic enzymes is true?&#10;A)Dosing may be titrated according to the decrease of steatorrhea.&#10;B)The amount of carbohydrates in a meal drives the amount of enzyme used.&#10;C)The amount of medication used increases with a cystic fibrosis pulmonary flare.&#10;D)The U.S. Food and Drug Administration (FDA) and internet-available formulations are bioequivalent.&#10;

Accepted Answer

Dosing of pancreatic enzymes can be titrated based on the clinical response, such as the decrease of steatorrhea, to achieve optimal symptom control and nutritional status in patients requiring enzyme replacement therapy, such as those with pancreatic insufficiency.

Question 5

Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secretions. Each replacement drug has lipase, protease, and amylase components, but the drug is prescribed in units of:

A)Lipase
B)Protease
C)Amylase
D)Pancreatin

Accepted Answer

Enzyme replacement drugs for cystic fibrosis are prescribed in units of lipase because the primary goal is to aid in the digestion of fats, which requires lipase. Lipase dosage is critical for effective fat absorption and nutritional support.

Question 6

Elderly patients who are on levothyroxine for thyroid replacement should be monitored for:&#10;A)Excessive sedation&#10;B)Tachycardia and angina&#10;C)Weight gain&#10;D)Cold intolerance&#10;

Accepted Answer

Levothyroxine is a synthetic form of thyroid hormone used to treat hypothyroidism. In elderly patients, excessive doses can lead to symptoms of hyperthyroidism such as tachycardia (rapid heart rate) and angina (chest pain), due to the increased metabolic rate and demand on the heart.

Question 7

A postsurgical patient may experience water balance issues for a while due to alteration in which hypothalamic, pituitary, adrenal hormone:&#10;A)Prolactin&#10;B)Thyroid-stimulating hormone (TSH)&#10;C)Antidiuretic hormone (ADH)&#10;D)Oxytocin&#10;

Accepted Answer

Antidiuretic hormone (ADH), also known as vasopressin, is produced in the hypothalamus and released by the posterior pituitary gland. It plays a crucial role in regulating water balance in the body by controlling the amount of water reabsorbed by the kidneys. Alterations in ADH secretion or action can lead to issues with water balance, such as dehydration or fluid retention, which may be observed in post-surgical patients.

Question 8

Why must steroids be tapered after long-term use?&#10;A)Chronic use intensifies adrenal response.&#10;B)So that the resolution of longer-term adrenal suppression is not rapid.&#10;C)Tapering reduces the sequela of &#34;moon facies&#34; and lipomas.&#10;D)Abrupt cessation causes tachyphylaxis.&#10;

Accepted Answer

Steroids mimic the body's natural hormones, and long-term use suppresses the adrenal glands' production of these hormones. Tapering off steroids allows the adrenal glands time to resume their normal function gradually, avoiding potential adrenal insufficiency.

Question 9

A precaution when sprinkling pancreatic enzymes on food is:&#10;A)Wash off any &#34;dust&#34; that gets on the hands to decrease potential dermatology issues.&#10;B)Keep it on top of food instead of mixing it in.&#10;C)Do not drink fluids during the meal.&#10;D)Keep the powder primarily on the carbohydrate-rich foods.&#10;

Accepted Answer

Pancreatic enzyme powder can cause irritation or damage to the skin, so it is important to wash off any residue that comes into contact with the skin to prevent dermatological issues.

Question 10

Patients with Addison's disease frequently carry an emergency supply of which medication in case of sudden onset crisis:&#10;A)Adrenaline&#10;B)Aldosterone&#10;C)Florinef&#10;D)Benadryl&#10;

Accepted Answer

Florinef (fludrocortisone) is commonly carried by patients with Addison's disease for emergency use. It acts as a synthetic corticosteroid, helping to replace the deficient hormones in Addison's disease, particularly in situations of crisis where the body's requirement for these hormones increases.

Question 11

A woman who is not pregnant and not breastfeeding has unexplained &#34;milk production&#34; from her left breast. Which endocrine abnormality is the most likely cause?&#10;A)Adrenal tumor&#10;B)Pancreatic cancer&#10;C)Cushing's syndrome&#10;D)Pituitary tumor&#10;

Accepted Answer

The answer of A woman who is not pregnant and...

Question 12

Different brands of pancreatic enzyme replacement drugs are:&#10;A)Bioequivalent&#10;B)About the same in cost per unit of lipase across brands&#10;C)Able to be interchanged between generic and brand-name products to reduce cost&#10;D)None of the above&#10;

Accepted Answer

The answer of Different brands of pancreatic enzyme replacement drugs...

Deck 19: Drugs Affecting the Endocrine System