Deck 25: Therapeutic Agents for the Immune System

Question 1

Which of the following is(are) autoimmune disorders?

A) Systemic lupus erythematosus (SLE)
B) Psoriasis
C) Rheumatoid arthritis (RA)
D) All of the above

Answer 1

All of the above

Question 2

Propylthiouracil is used:

A) To decrease thyroid production in Graves disease
B) As a thyroid supplement
C) To treat hypothyroidism
D) A and C

Answer 2

To decrease thyroid production in Graves disease

Question 3

Which of the following statements is(are) true regarding cytokines?

A) Cytokines are secreted by a variety of cells, including immune cells.
B) They signal inflammation and the activation of immune responses.
C) Cytokines include tumor necrosis factor (TNF) and interleukin-1 (IL-1).
D) All of the above are true statements.

Answer 3

All of the above are true statements.

Question 4

A major side effect with immunosuppressive therapy is:

A) Nausea and vomiting
B) Increased risk of infection
C) Cough
D) B and C

Question 5

Chronic inflammation can:

A) Occur locally or systemically
B) Lead to the development of scar tissue
C) Alter an organ's ability to function optimally
D) All of the above are characteristics of chronic inflammation

Question 6

Belimumab (Benlysta) for SLE is available:

A) Orally
B) Topically
C) Intravenously (IV)
D) All of the above

Question 7

The most common cause of hypothyroidism in the United States is which one of the following autoimmune diseases?

A) Hashimoto thyroiditis
B) SLE
C) RA
D) Type I diabetes

Question 8

Hematopoiesis is:

A) Blood cell production
B) Blood cell destruction
C) Ratio of white-to-red blood cells
D) Disease of the blood cells

Question 9

Side effects for azathioprine (Imuran) include:

A) Bone marrow suppression
B) Nausea and vomiting
C) Increased risk of infection
D) All of the above

Question 10

Which of the following statements does not describe the spleen?

A) The spleen contains macrophages.
B) It is made up of red pulp and white pulp.
C) The spleen is the largest lymphatic organ.
D) It filters blood cells at the beginning of their life cycle.

Question 11

Which of the following medications for rheumatoid arthritis can be orally administered?

A) Methotrexate
B) Etanercept
C) Adalimumab
D) Abatecept

Question 12

Which of the following is not a major organ in the lymphatic system?

A) Thymus
B) Kidneys
C) Bone marrow
D) Spleen

Question 13

Which organ produces lymphocytes and gradually shrinks as a person ages?

A) Thymus
B) Tonsils
C) Spleen
D) Pancreas

Question 14

RA:

A) Is a disease that predominately affects older adults
B) Is curable with prednisone and non-steroidal anti-inflammatory drugs (NSAIDs)
C) Leads to irreversible joint deformity
D) Affects men more than women

Question 15

Propylthiouracil and methimazole are used to treat:

A) RA
B) Hyperthyroidism
C) Hypothyroidism
D) SLE

Question 16

DMARDs are:

A) Disease-modifying anti-inflammatory drugs
B) Disease-modifying action drugs
C) Disease-modifying antirheumatic drugs
D) Disease-modifying aggravating drugs

Question 17

Methotrexate (Rheumatrex) for RA can be orally administered:

A) Once weekly as a single dose
B) Every 12 hours for three doses once weekly
C) Daily
D) A or B

Question 18

Humira is indicated for the treatment of:

A) Crohn Disease
B) Psoriasis
C) Rheumatoid Arthritis
D) All of the above

Question 19

Graves disease is an autoimmune disease that:

A) Leads to hypothyroidism
B) Leads to hyperthyroidism
C) Can be treated with thyroid supplements
D) A and C

Question 20

Rapamune and Nulojix are indicated for:

A) Prevention of kidney transplant rejection
B) SLE
C) RA
D) Prevention of shingles

Question 21

What happens when a vaccine requiring storage between 2° and 8° C is frozen?

A) The vaccine must be slowly thawed to the proper temperature before administering.
B) Vaccines may be kept frozen until 24 hours before administering.
C) The vaccine may be ineffective and should not be administered.
D) Freezing the vaccine extends the expiration date by 6 months.

Question 22

Vaccines are available for:

A) Bacterial and viral diseases
B) Fungal infections
C) Parasitic infections
D) All of the above

Question 23

Zostavax is indicated for the prevention of:

A) Chickenpox
B) Shingles
C) Haemophilus influenzae
D) Tetanus

Question 24

Why is it important for a pharmacy technician to have a record of up-to-date immunizations?

A) Many hospitals require proof of childhood immunizations before hiring technicians.
B) Many hospitals require proof of childhood immunizations before providing externships.
C) Records can provide information to avoid numerous blood tests to prove previous immunizations.
D) All of the above statements apply.

Question 25

The brand name for the biologic response modifier (BRM) etanercept is:

A) Humira
B) Enbrel
C) Remicade
D) Cimzia

Question 26

Which of the following would not be considered an antigen?

A) Virus
B) Foreign substance that causes a disease
C) Foreign substance that causes no reaction
D) Foreign substance that causes an allergy

Question 27

If a person steps on a rusty nail and has not had a booster in 10 years, then he or she should get a:

A) Tetanus toxoid
B) Diphtheria-pertussis-tetanus (DPT) vaccination
C) Tetanus antitoxin
D) Tetanus booster

Question 28

Attenuated, in reference to vaccines, means :

A) Dead
B) Weakened
C) Potent
D) Viral

Question 29

Twinrix is indicated for:

A) DTaP
B) Haemophilus influenzae type b-hepatitis B
C) Hepatitis A and B
D) Influenza type A and B

Question 30

Pnuemovax 23 is administered:

A) Intravenously
B) Orally
C) Subcutaneously of intramuscularly
D) Through the nose by inhalation

Question 31

Tetanus toxoid:

A) Is an active bacterial toxin
B) Is not necessary for those older than 18 years of age
C) Requires a booster every 10 years
D) A and B

Question 32

Remicade is the brand name for:

A) Adalimumab
B) Everolimus
C) Golimumab
D) Infliximab

Question 33

Most vaccines require:

A) Refrigeration between 2° and 8° C
B) Freezing
C) Careful temperature monitoring during shipping and storage
D) A and C

Question 34

Many diseases that were previously responsible for illnesses and deaths are now rare because:

A) Immunizations have widespread use
B) Humans have naturally developed antibodies
C) Better sanitation practices exist worldwide today
D) More people visit physicians

Question 35

Which of the following statements is(are) true about the vaccination Gardasil?

A) Gardasil is administered to prevent HPV.
B) It is licensed for use in male and female children and young adults (9 to 26 years of age).
C) Gardasil is given IV.
D) A and B.

Question 36

Which of the following statements is true of live vaccines?

A) Live vaccines lead to the development of active acquired immunity
B) Periodic booster shots are required
C) Live vaccines carry no risk of infection
D) Live vaccines are always effective

Question 37

What agents contain antibodies that can neutralize dangerous toxins?

A) Antitoxins
B) Antivenins
C) Antibiotics
D) A and B

Question 38

Which of the following statements is(are) true concerning an inactivated viral vaccine?

A) The immune system recognizes the viral capsid (outer covering).
B) Boosters must be administered.
C) The virus is attenuated.
D) A and B

Question 39

An EpiPen is indicated for

A) Anaphylaxis
B) Graves Disease
C) Rheumatoid arthritis
D) Systemic Lupus Erythematosus

Question 40

When a vaccine is administered the patient or their caregiver receives a:

A) MedGuide
B) Patient product insert
C) VIS
D) Both A and B