Deck 28: Therapeutic Agents for the Hematologic System

Question 1

Which category of chemotherapy medications is a group of alkaloids derived from plants?

A) Mitotic inhibitors
B) Antibiotics
C) Alkylating agents
D) Nitrosoureas

Answer 1

Mitotic inhibitors

Question 2

Which of the following statements is(are) true regarding erythrocytes?

A) Erythrocytes are red blood cells (RBCs).
B) They contain hemoglobin.
C) They fight infection.
D) Erythrocytes are RBCs that contain hemoglobin.

Answer 2

Erythrocytes are RBCs that contain hemoglobin.

Question 3

Low albumin concentration in the blood can lead to:

A) Hypertension
B) Edema
C) Hypotension
D) Hyperproteinemia

Answer 3

Edema

Question 4

Which of the following blood components is essential to clotting?

A) Albumin
B) Plasma
C) Platelets
D) Erythrocytes

Question 5

Which of the following medications are not associated with drug-induced thrombocytopenia (low platelet count)?

A) Heparin
B) Vancomycin
C) Phenytoin
D) All of the above

Question 6

Granulocytopenia is a reduction in the number of:

A) Neutrophils
B) Eosinophils
C) Basophils
D) All of the above

Question 7

What is the term for an increase in the total cell mass of the blood?

A) Erythropoiesis
B) Hemophilia
C) Polycythemia
D) Leukopenia

Question 8

Which of the following is(are) functions of the blood?

A) Carrying waste from tissues and organs
B) Delivering oxygen and nutrients to tissues and organs
C) Transporting immune cells to sites of infection and injury
D) All of the above

Question 9

What element is necessary for the production of hemoglobin?

A) Sodium
B) Potassium
C) Iron
D) Zinc

Question 10

Erythropoietin:

A) Is a hormone produced by the kidney
B) Stimulates RBC production
C) Can be used to treat some types of anemia
D) All of the above are characteristics of erythropoietin

Question 11

What is the primary treatment for iron-deficiency anemia?

A) Spinach
B) Blood transfusions
C) Oral iron supplements
D) Intravenous (IV) iron

Question 12

Which type of anemia is caused by a vitamin B₁₂ deficiency attributable to congenital or acquired deficiency of intrinsic factor (IF)?

A) Folate-deficiency anemia
B) Iron-deficiency anemia
C) Pernicious anemia
D) Sickle cell anemia

Question 13

Eltrombopag (Promacta) for the treatment of thrombocytopenia increases ______________ production.

A) white blood cell
B) platelet
C) RBC
D) albumin

Question 14

The combination therapies of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) and mustard, oncovin , procarbazine, and prednisone (MOPP) are commonly used for:

A) Chronic lymphocytic leukemia
B) Chronic myeloid leukemia
C) Acute lymphoblastic leukemia
D) Hodgkin disease

Question 15

Which one of the following generics is not an antibiotic used in chemotherapy?

A) Bleomycin
B) Cyclophosphamide
C) Mitomycin
D) Daunorubicin

Question 16

Which of the following statements is(are) true of filgrastim (Neupogen)?

A) Filgrastim is administered orally.
B) It should not be shaken before administering.
C) Filgrastim is used to treat neutropenia.
D) B and C are true statements.

Question 17

In which form of anemia do RBCs take on an abnormal shape?

A) Folate-deficiency anemia
B) Iron-deficiency anemia
C) Pernicious anemia
D) Sickle cell anemia

Question 18

Which of the following categories of chemotherapeutic agents can cross the blood-brain barrier to reach cancers of the brain?

A) Antibiotics
B) Nitrosoureas
C) Antimetabolites
D) Nitrogen mustards

Question 19

Antimetabolite agents:

A) Work by interfering with cancer cell reproduction
B) Have extreme side effects
C) Are often used to treat leukemia
D) All of the above are characteristics of antimetabolites

Question 20

Idiopathic thrombocytopenia is caused by:

A) Pregnancy
B) Drugs
C) Bleeding
D) Unknown factors

Question 21

The generic name for Epogen is:

A) Darbepoetin alfa
B) Epoetin alfa
C) Filgrastim
D) Pegfilgrastim

Question 22

Epogen is administered:

A) Once a week
B) Three times a week
C) Once a month
D) Twice a month

Question 23

Adverse effects of Droxia include all of the following EXCEPT:

A) Anemia
B) Constipation
C) Leukopenia
D) neutropenia

Question 24

Etoposide is the generic name for:

A) Campath
B) Purinethol
C) Rituxan
D) Toposar

Question 25

Which one of the following statements is true concerning leukemia?

A) Leukemia is a genetic disorder.
B) It is caused by environmental factors.
C) Both genetic and environmental factors can contribute to the development of leukemia.
D) Leukemia is contagious.

Question 26

Which of the following statements is(are) true regarding the use of warfarin?

A) Avoid aspirin and non-steroidal anti-inflammatory drugs (NSAIDs).
B) Eat extra foods containing vitamin K.
C) Occasionally skipping a dose is okay.
D) A and B are true statements.

Question 27

The generic name for Feosol is:

A) Iron polysaccharide
B) Ferrous sulfate
C) Ferrous gluconate
D) Ferrous fumarate

Question 28

Eltrombopag (Promacta) for thrombocytopenia requires which one of the following auxiliary labels?

A) Take on an empty stomach.
B) Take with food or milk.
C) Take at least 1 hour before or 2 hours after meals.
D) Take on an empty stomach at least 1 hour before or 2 hours after meals.

Question 29

Leukemia involves the production of:

A) High number of cancerous stem cells that replace normal white blood cells in the bone marrow
B) Large number of RBCs
C) Too many platelets
D) Too much albumin

Question 30

Desmopressin (DDAVP) may be administered by the following routes except:

A) Intravenously and subcutaneously
B) Topically
C) Intranasally
D) Orally

Question 31

Side effects of iron therapy may include:

A) Nausea and vomiting
B) Constipation
C) Dark stools
D) All of the above

Question 32

Hydroxyurea is administered:

A) Intramuscularly
B) Intravenously
C) Orally
D) Subcutaneously

Question 33

Stage _____ of cancer is the most advanced form.

A) I
B) II
C) III
D) IV

Question 34

Which of the following is not considered a granulocyte?

A) Lymphocyte
B) Neutrophil
C) Eosinophil
D) Basophil

Question 35

Which vitamin may be prescribed by a physician with oral iron supplements?

A) Vitamin A
B) Vitamin B₆
C) Vitamin C
D) Vitamin K

Question 36

The treatment for polycythemia vera can include:

A) Phlebotomy
B) Hydroxyurea
C) Erythropoietin
D) A and B

Question 37

DDAVP increases plasma factor VIII and von Willebrand factor and is used to treat:

A) von Willebrand disease
B) Hemophilia A
C) Surgical bleeding
D) All of the above