Deck 19: Therapeutic Agents for the Musculoskeletal System

Question 1

The only COX-2 inhibitor available in the United States is:

A) Celebrex
B) Vioxx
C) Mobic
D) Motrin

Answer 1

Celebrex

Question 2

What is the most severe side effect of opioid medications?

A) Gastrointestinal (GI) upset
B) Respiratory depression
C) Drowsiness
D) Constipation

Answer 2

Respiratory depression

Question 3

Both depolarizing and non-depolarizing neuromuscular-blocking agents affect the neurotransmitter ______________.

A) epinephrine
B) norepinephrine
C) dopamine
D) acetylcholine

Answer 3

acetylcholine

Question 4

Opioid analgesics require the following auxiliary label(s):

A) May cause dizziness or drowsiness
B) Avoid alcohol
C) "Caution: Federal law prohibits the transfer of this drug to any person other than the patient for whom it was prescribed."
D) All of the above auxiliary labels are required for opioid analgesic medications

Question 5

All of the following osteoporosis agents are in the same class except:

A) Fosamax
B) Boniva
C) Actonel
D) Evista

Question 6

All of the following medications have antipyretic, anti-inflammatory, and analgesic effects except:

A) Aspirin
B) Acetaminophen
C) Ibuprofen
D) Naproxen

Question 7

Skeletal muscle relaxants require which one of the following auxiliary labels?

A) Take with a full glass of water.
B) Take on an empty stomach.
C) Avoid grapefruit juice.
D) May cause dizziness or drowsiness. Avoid alcohol.

Question 8

Reye syndrome has been linked to what medication?

A) Acetaminophen
B) Diphenhydramine
C) Acetylsalicylic acid
D) None of the above

Question 9

Which one of the following drugs is a schedule III controlled substance (C-III) medication?

A) Tylenol with codeine
B) Ultram
C) Percocet
D) Duragesic

Question 10

Opioid analgesics:

A) Treat the cause of the pain
B) Are scheduled and potentially addictive medications
C) Block the perception of pain in the CNS
D) Both B and C accurately describe opioid analgesics

Question 11

Which of the following osteoporosis agents can be intravenously (IV) administered?

A) Actonel
B) Boniva
C) Fosamax
D) A and B

Question 12

Osteoporosis:

A) Is a systemic skeletal disease
B) Occurs when bone breaks down faster than it can be rebuilt
C) Leads to fragile bones
D) All of the above are accurate descriptions of osteoporosis

Question 13

Baclofen (Lioresal) belongs to what classification of medication?

A) Skeletal muscle relaxants
B) NSAIDs
C) Osteoporosis agents
D) Analgesics

Question 14

Which of the following risk factors contribute(s) to the development of osteoarthritis?

A) Advanced age
B) Obesity
C) Overuse and trauma of the joints
D) All of the above

Question 15

Generic ibuprofen is marketed as:

A) Advil
B) Naprosyn
C) Motrin
D) A and C

Question 16

Why would acetaminophen be chosen over aspirin for a patient taking warfarin?

A) Acetaminophen is a more effective antiinflammatory agent.
B) Acetaminophen does not inhibit platelet action.
C) Acetaminophen is a risk-free medication.
D) None of the above statements apply.

Question 17

Which organ is affected by an overdose of acetaminophen?

A) Kidney
B) Liver
C) Heart
D) Bladder

Question 18

All of the following statements are true about gout except:

A) Gout is a form of arthritis
B) It can be exacerbated by the intake of alcohol
C) Gout is not related to diet
D) It can be treated with colchicine

Question 19

Which of the following is not a function of the musculoskeletal system?

A) Structural support and protection
B) Facilitates movement
C) Storage site for sodium and potassium
D) Storage bank for calcium and phosphorus

Question 20

A negative GI side effect associated with first-generation non-steroidal antiinflammatory drugs (NSAIDs) is due to:

A) Inhibiting cyclooxygenase-1 (COX-1) enzymes
B) Inhibiting cyclooxygenase-2 (COX-2) enzymes
C) Inhibiting COX-1 and COX-2 enzymes
D) Stimulating COX-1 and COX-2 enzymes

Question 21

Which medication can be used to reverse the effects of opioid analgesics?

A) Hydromorphone (Dilaudid)
B) Meperidine (Demerol)
C) Naloxone (Narcan)
D) Codeine

Question 22

Vicodin is classified as a:

A) Schedule II Controlled Substance
B) Schedule III Controlled Substance
C) Schedule IV Controlled Substance
D) Schedule V Controlled Substance

Question 23

Narcan is the brand name for:

A) Buprenorphine
B) Nalaxone
C) Nalbuphine
D) Naltrexone

Question 24

What is the generic name for Vicodin?

A) Codeine + acetaminophen
B) Hydrocodone + acetaminophen
C) Hydromorphone
D) Meperidine

Question 25

Which of the following auxiliary labels should be affixed to a bisphosphonate prescription bottle?

A) Take on an empty stomach
B) With a full glass of water at least before eating any food or taking other medications
C) Should remain upright for 30 to 60 minutes
D) All of the above

Question 26

Which OTC supplements can be taken to help prevent osteoporosis?

A) Vitamin D and calcium
B) Vitamin E and calcium
C) Evista and calcium
D) Iron and calcium

Question 27

Which of the following medications should bear the following auxiliary label: Caution: Federal law prohibits the transfer of this drug to any person other than the patient for whom it was prescribed?

A) Colchicine
B) Flexeril
C) Soma
D) Zanaflex

Question 28

Fosamax, Actonel, and Evista are all used for:

A) Osteoporosis
B) Osteoarthritis
C) Gout
D) Skeletal muscle pain

Question 29

The role of the skeletal system is to:

A) Provide support for the body
B) Protect internal organs
C) Facilitate movement
D) All of the above are roles of the skeletal system

Question 30

Which medication(s) inhibit(s) COX-1 and COX-2 enzymes?

A) Celebrex
B) Tylenol
C) Vicodin
D) B and C

Question 31

Why does acetaminophen not have an antiinflammatory effect?

A) Acetaminophen does not inhibit cyclooxygenase.
B) It only inhibits COX-2 enzymes.
C) Acetaminophen only inhibits cyclooxygenase within the CNS.
D) None of the above answers apply.

Question 32

The maximum dose for aspirin in adults is:

A) 2 g per day
B) 3 g per day
C) 4 g per day
D) 6 g per day

Question 33

Bones serve as storage areas for which mineral(s)?

A) Calcium
B) Sodium
C) Phosphorus
D) A and C

Question 34

Which of the following medications is available as an IR, DR, and XR dosage form?

A) Celecoxib
B) Diclofenac
C) Indomethacin
D) Oxaprozin

Question 35

The risk of a gout attack can be reduced if a patient avoids:

A) Beef
B) Chicken
C) Lamb
D) A and C

Question 36

An antipyretic medication is used to:

A) Reduce pain
B) Reduce fever
C) Prevent gout
D) Treat gout

Question 37

Which of the following medications is a combination product that includes acetaminophen?

A) Ultram
B) Percocet
C) Robaxin
D) Dilaudid

Question 38

Which medication do many people take for the prophylaxis (prevention) of heart attacks and strokes?

A) Aspirin
B) Acetaminophen
C) Ibuprofen
D) Calcium

Question 39

Osteoarthritis is considered to be a(an):

A) Autoimmune disease
B) Degenerative joint disease
C) Musculoskeletal disease
D) A and B

Question 40

The maximum recommended daily dose of acetaminophen for healthy adults is _________ mg.

A) 1000
B) 2000
C) 3000
D) 4000