Deck 4: Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Question 1

Functions of an activated T lymphocyte include

A)proliferation and differentiation.
B)production of cytokines.
C)development of effector function.
D)All of the above.

Answer 1

All of the above.

Question 2

The CD cell surface membrane marker that appears during the first stage of T lymphocyte development and remains present as an identifying marker to T lymphocytes is

A)CD2.
B)CD4.
C)CD8.
D)CD10.

Answer 2

CD2.

Question 3

Match the T cell populations with the appropriate description.
Helper T type 2 (Th2)

A)Play a greater role in the regulation of antibody production and the release of cytokines required for B cell differentiation
B)Responsible for cell-mediated effector mechanisms
C)An immunoregulatory type of Th cells

Answer 3

Play a greater role in the regulation of antibody production and the release of cytokines required for B cell differentiation

Question 4

Which characteristic is not associated with B lymphocytes?

A)Demonstrate surface immunoglobulin (sIg)
B)Differentiate into plasma cells with antigenic stimulation
C)Participate in an anamnestic response as memory cells
D)Can directly lyse a foreign antigen

Question 5

Match the lymphoid organs with the approximate percentage of T lymphocytes.
See Table 4-1.

Lymph nodes

A)80%
B)60%
C)20%
D)10%

Question 6

In antigen recognition by T lymphocytes, each cell

A)is clonally restricted.
B)expresses a receptor able to react with a given peptide.
C)can only recognize a limited number of antigens.
D)All of the above.

Question 7

Match the lymphoid organs with the approximate percentage of T lymphocytes.
See Table 4-1.

Blood

A)80%
B)60%
C)20%
D)10%

Question 8

What is the source of undifferentiated T lymphocytes?

A)Bone marrow
B)Lymph nodes
C)Liver and spleen
D)Thymus

Question 9

Surface markers on lymphocytes can be used to

A)identify and count CD4+ and CD8+ cells.
B)classify leukemic cells.
C)monitor patients on immunotherapy.
D)All of the above.

Question 10

Diminished immunoglobulin levels can be related to

A)a deficit of activated T lymphocytes.
B)impaired phagocytosis.
C)lack of complement production.
D)overproduction of B lymphocytes.

Question 11

Match the lymphoid organs with the appropriate classification.
Bone marrow

A)Primary
B)Secondary

Question 12

Match the T cell populations with the appropriate description.
Regulatory T (Treg)

A)Play a greater role in the regulation of antibody production and the release of cytokines required for B cell differentiation
B)Responsible for cell-mediated effector mechanisms
C)An immunoregulatory type of Th cells

Question 13

Cluster designation (CD) antigens are involved in various lymphocyte functions, which can include

A)promotion of cell-to-cell interactions and adhesion.
B)transduction of signals that lead to lymphocyte activation.
C)detection of cytokine secretion.
D)Both A and B.

Question 14

Match the T cell populations with the appropriate description.
Helper T type 1 (Th1)

A)Play a greater role in the regulation of antibody production and the release of cytokines required for B cell differentiation
B)Responsible for cell-mediated effector mechanisms
C)An immunoregulatory type of Th cells

Question 15

Mature T lymphocytes survive for ________ compared with B lymphocytes, which survive for a few days.

A)a few hours
B)several months
C)years
D)Either B or C

Question 16

Match the lymphocyte types with the appropriate characteristic.
Natural Treg cells

A)Effector cells that can directly destroy virally infected target cells
B)Downregulate the actions of other T and B cells
C)Relatively high avidity for self-antigens

Question 17

When mature T lymphocytes leave the thymus, their T cell receptors are either CD4+ or

A)CD2+.
B)CD8+.
C)CD19+.
D)CD31+.

Question 18

The T cell receptor (TCR) recognizes an antigen

A)when it is coated with antibody.
B)when it is coated with complement.
C)as a peptide bonded to an MHC class II molecule on the surface of an antigen-presenting cell.
D)as a free-floating antigen in the peripheral blood or lymphatic circulation.

Question 19

Match the lymphoid organs with the appropriate classification.
Lymph nodes

A)Primary
B)Secondary

Question 20

Match the lymphoid organs with the approximate percentage of T lymphocytes.
See Table 4-1.

Bone marrow

A)80%
B)60%
C)20%
D)10%

Question 21

Match the lymphocyte types with the appropriate description.
K-type lymphocytes

A)Lead to antibody production
B)Destroy target cells through an extracellular nonphagocytic mechanism (cytotoxic reaction)
C)Kill target cells sensitized with antibody

Question 22

Match the lymphocyte types with the appropriate description.
Natural killer cells

A)Lead to antibody production
B)Destroy target cells through an extracellular nonphagocytic mechanism (cytotoxic reaction)
C)Kill target cells sensitized with antibody

Question 23

Match the lymphocyte types with the appropriate characteristic.
Suppressor T lymphocytes or T suppressor (Ts) cells

A)Effector cells that can directly destroy virally infected target cells
B)Downregulate the actions of other T and B cells
C)Relatively high avidity for self-antigens

Question 24

Match the lymphocyte types with the appropriate characteristic.
Cytotoxic T lymphocytes, or T cytotoxic (Tc) cells

A)Effector cells that can directly destroy virally infected target cells
B)Downregulate the actions of other T and B cells
C)Relatively high avidity for self-antigens

Question 25

Match the lymphocyte types with the appropriate description.
B lymphocytes

A)Lead to antibody production
B)Destroy target cells through an extracellular nonphagocytic mechanism (cytotoxic reaction)
C)Kill target cells sensitized with antibody