Deck 19: Toxoplasmosis

Question 1

Match the types of bonding with the correct definition.
Symptoms of acquired T. gondii infection can

A)be mild.
B)resemble infectious mononucleosis.
C)cause a urinary tract infection.
D)Both A and B.

Answer 1

Both A and B.

Question 2

Match the types of bonding with the correct definition.
Any positive result in a pregnant patient confirmed as positive by a second reference laboratory should be evaluated by

A)amniocentesis testing by PCR for T. gondii.
B)IgM, IgA, and IgE ELISAs.
C)Sabin-Feldman dye test (IgG).
D)IgE immunosorbent agglutination assay.

Answer 2

amniocentesis testing by PCR for T. gondii.

Question 3

Match the types of bonding with the correct definition.
The preferred method for detection of T. gondii is

A)culture.
B)ELISA.
C)IFA.
D)PCR.

Answer 3

ELISA.

Question 4

Match the types of bonding with the correct definition.
The avidity result is determined using

A)ratios of antibody titration curves of urea-treated and untreated sera.
B)titers of antibody in preinfection and postinfection specimens.
C)amniotic fluid versus serum.
D)Both B and C.

Question 5

Match the types of bonding with the correct definition.
IgM antibodies to T. gondii in an adult are an indication of

A)current or recent infection.
B)chronic infection.
C)past infection.
D)antibody transmitted from another person.

Question 6

Match the types of bonding with the correct definition.
The definitive host of Toxoplasma gondii is the

A)dog.
B)house cat.
C)chicken.
D)rodent class.

Question 7

Match the types of bonding with the correct definition.
Transfusion-transmitted toxoplasmosis is associated with

A)packed red blood cells.
B)platelet concentrates.
C)leukocyte concentrates.
D)Either B or C.

Question 8

Match the types of bonding with the correct definition.
Major sources of increasing human infection with T. gondii include all the following except

A)fecal contamination of food with the T. gondii organism.
B)infected meat.
C)bloody body fluids.
D)raw infected milk.

Question 9

Match the types of bonding with the correct definition.
The best evidence of toxoplasmosis infection is a significant change in

A)two appropriately timed specimens.
B)acute and convalescent specimens.
C)two appropriate specimens analyzed at the same time in the laboratory.
D)All of the above.

Question 10

Match the types of bonding with the correct definition.
Toxoplasma-infected mothers who are not treated can give birth to a(n)

A)less than term infant.
B)underweight infant.
C)congenitally infected infant.
D)normal, healthy infant.

Question 11

Match the types of bonding with the correct definition.
Congenital toxoplasmosis can result in

A)central nervous system (CNS) malformation.
B)prenatal mortality.
C)congenital heart defects.
D)Both A and B.

Question 12

Match the types of bonding with the correct definition.
Toxoplasma gondii antibody assay can demonstrate antibodies within __________ after infection.

A)2 days
B)1 week
C)2 weeks
D)1 month

Question 13

Match the types of bonding with the correct definition.
The Centers for Disease Control and Prevention (CDC) suggests that any confirmed equivocal or ____________ test results for toxoplasmosis should be retested using a different assay.

A)positive
B)negative
C)questionable
D)prenatal

Question 14

Match the types of bonding with the correct definition.
The PCR assay for T. gondii can be performed on

A)serum or plasma.
B)fresh or frozen biopsy tissue.
C)cerebrospinal fluid.
D)All of the above.

Question 15

Match the types of bonding with the correct definition.
After IgM-positive sera undergo confirmatory testing, the results are interpreted as a(n)

A)recently acquired infection.
B)infection acquired in the past.
C)false-positive test result.
D)All of the above.

Question 16

Match the types of bonding with the correct definition.
All mammals can transmit T. gondii by

A)casual contact.
B)transplacental transmission.
C)sexual contact.
D)None of the above.