Deck 11: Pharmacology

Question 1

CP is a 30 yo female who is meeting with a physician to consider Roux-en-Y gastric bypass surgery.
HT: 5'3" WT: 234# UBW: 201# (2 years ago)
The use of drugs for treatment of disease and health maintenance is known as:

A)pharmacology.
B)pharmacokinetics.
C)pharmacotherapy.
D)pharmacodynamics.

Answer 1

C

Question 2

CP is a 30 yo female who is meeting with a physician to consider Roux-en-Y gastric bypass surgery.
HT: 5'3" WT: 234# UBW: 201# (2 years ago)
The study of drug absorption, distribution, metabolism, and excretion is known as:

A)pharmacology.
B)pharmacodynamics.
C)pharmacokinetics.
D)pharmacotherapy.

Answer 2

C

Question 3

Which of the following diseases has the greatest negative impact on the effectiveness of drug absorption?

A)diabetes
B)Crohn's disease
C)Huntington's disease
D)Cushing's disease

Answer 3

B

Question 4

Which of the following is not an example of a pressor agent?

A)tyramine
B)histamine
C)dopamine
D)histidine

Question 5

The interaction between pressor agents in foods and monoamine oxidase inhibitors can result in:

A)a sudden decrease in blood pressure.
B)a sudden increase in blood sugar.
C)a sudden increase in blood pressure.
D)a sudden decrease in blood sugar.

Question 6

CP is a 30 yo female who is meeting with a physician to consider Roux-en-Y gastric bypass surgery.
HT: 5'3" WT: 234# UBW: 201# (2 years ago)
_____ are used to inhibit the production of _____, which causes a decrease in blood pressure

A)ACE inhibitors, angiotensin I
B)ACE inhibitors, angiotensin II
C)Proton-pump inhibitors, angiotensin I
D)Proton-pump inhibitors, angiotensin II

Question 7

What occurs after a drug is absorbed?

A)It moves to the stomach where it will be dissolved.
B)The drug will be biotransformed.
C)The drug will be metabolized.
D)The drug will move throughout the body to the target sites where it will act.

Question 8

When you are treating a patient taking a statin medication, you should advise her or him not to consume which of the following with this medication?

A)grapefruit
B)apples
C)limes
D)bananas

Question 9

Vitamin K affects what class of prescription drugs?

A)antidepressants
B)antibiotics
C)blood thinners
D)cholesterol-lowering agents

Question 10

CP is a 30 yo female who is meeting with a physician to consider Roux-en-Y gastric bypass surgery.
HT: 5'3" WT: 234# UBW: 201# (2 years ago)
The study of drugs, their properties, and their effects is known as:

A)pharmacology.
B)pharmacokinetics.
C)pharmacotherapy.
D)pharmacodynamics.

Question 11

What is the major organ where biotransformation occurs?

A)spleen
B)liver
C)kidneys
D)lymph nodes

Question 12

When treating kidney stones, dietary modification is intended to control

A)calcium excretion.
B)urine pH.
C)high blood pressure.
D)glucose levels.

Question 13

Medications are generally bound to which of the following protein carriers?

A)retinol-binding protein
B)albumin
C)transferrin
D)pre-albumin

Question 14

A patient taking MAOIs should avoid foods high in _____ in order to avoid life-threatening side effects

A)nitric acid
B)tyramine
C)sulfates
D)citric acid

Question 15

CP is a 30 yo female who is meeting with a physician to consider Roux-en-Y gastric bypass surgery.
HT: 5'3" WT: 234# UBW: 201# (2 years ago)
Which of the following is not an absorptive mechanism for drugs?

A)passive diffusion
B)active transport
C)facilitated diffusion
D)osmosis

Question 16

Which of the following medications does not affect gastric acidity?

A)antacids
B)proton-pump inhibitors
C)prokinetics
D)H₂ blockers

Question 17

Which of the following enhances the absorption of an Fe supplement?

A)citrus juice
B)tea
C)milk
D)carbonated beverages

Question 18

CP is a 30 yo female who is meeting with a physician to consider Roux-en-Y gastric bypass surgery.
HT: 5'3" WT: 234# UBW: 201# (2 years ago)
What has to occur before the absorption of a drug?

A)cooling
B)heating
C)lubrication
D)dissolution

Question 19

Statin drugs are used to treat

A)high blood pressure.
B)hyperlipidemia.
C)hyperglycemia.
D)pain.

Question 20

Which of the following is true regarding the effect of vomiting and diarrhea on drug absorption?

A)increases the time available for solubility and dissolution
B)decreases the time available for solubility and dissolution
C)typically has no effect on absorption
D)makes drug absorption impossible

Question 21

Long-term use of corticosteroids can have which of the following effects?

A)high cholesterol
B)osteoporosis
C)ulcers
D)high blood pressure

Question 22

You have a patient recently diagnosed with osteoporosis and achlorydria Your primary concern regarding recommending calcium supplements is:

A)the decreased absorption due to the lack of HCl secretion.
B)the increased absorption due to the excess secretion of HCl.
C)the decreased absorption due to excess secretion of HCl.
D)the increased absorption due to the lack of HCl secretion.

Question 23

Which of the following is not one of the dietary interventions for treating kidney stones?

A)decrease fat intake
B)increase water intake
C)limit protein intake
D)reduce oxalates

Question 24

Prozac, an antidepressant medication, is often associated with which of the following side effects?

A)decrease in appetite
B)decrease in metabolism
C)migraines
D)unplanned weight gain

Question 25

Case Study Multiple Choice
WD is an 86 yo F who is seen by the internal medicine physician because she has been feeling very depressed.The physician takes a full history from WD, which reveals that several medications have been prescribed to her by a variety of specialists.It seems that each specialist neglected to pay attention to the meds that WD was prescribed by her other doctors and the potential drug-nutrient interactions.
The physician's notes are as follows:
Current Medication Reason for Prescribing
St.John's wort WD read in a magazine that this helps with depression
Slow Fe (iron supplement) prior anemia
Warfarin history of embolic stroke
Omeprazole history of peptic ulcer
Tums upset stomach
Amoxicillin recent respiratory infection
Doxazosin incontinence
Allegra seasonal allergies
Lipitor high cholesterol
Vitamin E she heard it was "good for heart disease"
Diet hx
B- eggs D- cooked spinach
bacon chicken breast
orange juice mashed potatoes
fruit cocktail
L- Italian hoagie (salami, ham, cheddar cheese, lettuce, and tomato)
iced tea
What in WD's diet or medication history is of particular concern to the physician due to several reported drug interactions and potential to decrease effectiveness of medications?

A)the use of Fe supplements
B)her chronic use of Tums
C)prescription for Lipitor
D)her use of St.John's wort

Question 26

Case Study Multiple Choice
WD is an 86 yo F who is seen by the internal medicine physician because she has been feeling very depressed.The physician takes a full history from WD, which reveals that several medications have been prescribed to her by a variety of specialists.It seems that each specialist neglected to pay attention to the meds that WD was prescribed by her other doctors and the potential drug-nutrient interactions.
The physician's notes are as follows:
Current Medication Reason for Prescribing
St.John's wort WD read in a magazine that this helps with depression
Slow Fe (iron supplement) prior anemia
Warfarin history of embolic stroke
Omeprazole history of peptic ulcer
Tums upset stomach
Amoxicillin recent respiratory infection
Doxazosin incontinence
Allegra seasonal allergies
Lipitor high cholesterol
Vitamin E she heard it was "good for heart disease"
Diet hx
B- eggs D- cooked spinach
bacon chicken breast
orange juice mashed potatoes
fruit cocktail
L- Italian hoagie (salami, ham, cheddar cheese, lettuce, and tomato)
iced tea
You notice that WD is taking an iron supplement The physician confirms that he would like her to continue with this supplement How would you advise WD regarding potential negative drug-nutrient interactions?

A)do not take with a meal containing spinach
B)do not take with iced tea
C)do not take with orange juice
D)do not take with a meal containing bacon

Question 27

Case Study Multiple Choice
WD is an 86 yo F who is seen by the internal medicine physician because she has been feeling very depressed.The physician takes a full history from WD, which reveals that several medications have been prescribed to her by a variety of specialists.It seems that each specialist neglected to pay attention to the meds that WD was prescribed by her other doctors and the potential drug-nutrient interactions.
The physician's notes are as follows:
Current Medication Reason for Prescribing
St.John's wort WD read in a magazine that this helps with depression
Slow Fe (iron supplement) prior anemia
Warfarin history of embolic stroke
Omeprazole history of peptic ulcer
Tums upset stomach
Amoxicillin recent respiratory infection
Doxazosin incontinence
Allegra seasonal allergies
Lipitor high cholesterol
Vitamin E she heard it was "good for heart disease"
Diet hx
B- eggs D- cooked spinach
bacon chicken breast
orange juice mashed potatoes
fruit cocktail
L- Italian hoagie (salami, ham, cheddar cheese, lettuce, and tomato)
iced tea
You would also warn WD of which potential side effect of Nardil?

A)metallic taste
B)weight gain
C)loss of appetite
D)increased K excretion

Question 28

Patients taking catopril and cisplatin typically report which of the following side effects?

A)foul odor
B)bitter taste
C)metallic taste
D)sweet odor

Question 29

Case Study Multiple Choice
WD is an 86 yo F who is seen by the internal medicine physician because she has been feeling very depressed.The physician takes a full history from WD, which reveals that several medications have been prescribed to her by a variety of specialists.It seems that each specialist neglected to pay attention to the meds that WD was prescribed by her other doctors and the potential drug-nutrient interactions.
The physician's notes are as follows:
Current Medication Reason for Prescribing
St.John's wort WD read in a magazine that this helps with depression
Slow Fe (iron supplement) prior anemia
Warfarin history of embolic stroke
Omeprazole history of peptic ulcer
Tums upset stomach
Amoxicillin recent respiratory infection
Doxazosin incontinence
Allegra seasonal allergies
Lipitor high cholesterol
Vitamin E she heard it was "good for heart disease"
Diet hx
B- eggs D- cooked spinach
bacon chicken breast
orange juice mashed potatoes
fruit cocktail
L- Italian hoagie (salami, ham, cheddar cheese, lettuce, and tomato)
iced tea
You notice that WD is taking warfarin You would also advise her regarding which food that could potentially cause a drug-nutrient interaction?

A)spinach
B)iced tea
C)orange juice
D)bacon

Question 30

Case Study Multiple Choice
WD is an 86 yo F who is seen by the internal medicine physician because she has been feeling very depressed.The physician takes a full history from WD, which reveals that several medications have been prescribed to her by a variety of specialists.It seems that each specialist neglected to pay attention to the meds that WD was prescribed by her other doctors and the potential drug-nutrient interactions.
The physician's notes are as follows:
Current Medication Reason for Prescribing
St.John's wort WD read in a magazine that this helps with depression
Slow Fe (iron supplement) prior anemia
Warfarin history of embolic stroke
Omeprazole history of peptic ulcer
Tums upset stomach
Amoxicillin recent respiratory infection
Doxazosin incontinence
Allegra seasonal allergies
Lipitor high cholesterol
Vitamin E she heard it was "good for heart disease"
Diet hx
B- eggs D- cooked spinach
bacon chicken breast
orange juice mashed potatoes
fruit cocktail
L- Italian hoagie (salami, ham, cheddar cheese, lettuce, and tomato)
iced tea
The doctor is concerned about potential drug-nutrient interactions as a consequence of WD taking Allegra and Lipitor He consults the registered dietitian to have a look at WD's diet Which of the following in her diet history is of concern?

A)fruit cocktail
B)iced tea
C)spinach
D)Italian hoagie

Question 31

Case Study Multiple Choice
WD is an 86 yo F who is seen by the internal medicine physician because she has been feeling very depressed.The physician takes a full history from WD, which reveals that several medications have been prescribed to her by a variety of specialists.It seems that each specialist neglected to pay attention to the meds that WD was prescribed by her other doctors and the potential drug-nutrient interactions.
The physician's notes are as follows:
Current Medication Reason for Prescribing
St.John's wort WD read in a magazine that this helps with depression
Slow Fe (iron supplement) prior anemia
Warfarin history of embolic stroke
Omeprazole history of peptic ulcer
Tums upset stomach
Amoxicillin recent respiratory infection
Doxazosin incontinence
Allegra seasonal allergies
Lipitor high cholesterol
Vitamin E she heard it was "good for heart disease"
Diet hx
B- eggs D- cooked spinach
bacon chicken breast
orange juice mashed potatoes
fruit cocktail
L- Italian hoagie (salami, ham, cheddar cheese, lettuce, and tomato)
iced tea
Given the above, the physician decides to put WD on Nardil Which of the following from WD's diet history will you counsel WD on changing?

A)consumption of orange juice
B)consumption of bacon
C)consumption of salami, ham, and cheese
D)use of vitamin E supplements

Question 32

To prevent drug-nutrient interactions when administering enteral nutrition, the ASPEN guidelines recommend that clinicians _____

A)mix together medications that are intended to be administered through a feeding tube.
B)withhold enteral nutrition after administering medications.
C)add the medication directly to the enteral formula for administration.
D)choose liquid medication formulations whenever they are available.