Deck 4: Heredity and Evolution

ملء الشاشة (f)
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سؤال
Which is NOT true about random assortment?

A)There is a chance distribution of chromosomes to daughter cells.
B)It is an important source of genetic variation.
C)It produces new alleles.
D)It happens during meiosis.
E)It is important like recombination.
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سؤال
A trait is NOT expressed in heterozygotes, it is said to be

A)dominant.
B)codominant.
C)recessive.
D)homozygous dominant.
E)segregated.
سؤال
In Mendel's experiments, the tall parental (P)plants

A)were heterozygous for the allele for tallness.
B)were heterozygous at the locus-controlling height.
C)could NOT be crossed with short plants.
D)were homozygous for the allele for shortness.
E)were homozygous for the allele for tallness.
سؤال
Gregor Mendel

A)developed theories of evolutionary change.
B)discovered the structure of the DNA molecule.
C)studied characteristics that are influenced by several genetic loci.
D)discovered the fundamental principles of how traits are inherited.
E)developed the theory of inheritance of acquired characteristics.
سؤال
Which of the following is NOT inherited in a Mendelian fashion?

A)ABO blood type
B)Marfan syndrome
C)Achondroplasia
D)Phenylketonuria
E)Skin color
سؤال
The ABO blood type system consists of ______ alleles.

A)6
B)4
C)3
D)2
E)5
سؤال
Two people (both heterozygotes)are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T). The inability to taste PTC is caused by a recessive allele (t). What proportion of their offspring would be expected to be heterozygous?

A)3/4
B)1/2
C)All
D)1/4
E)2/3
سؤال
Two people (both heterozygotes)are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T). The inability to taste PTC is caused by a recessive allele (t). What proportion of their children would be expected to have the ability to taste PTC?

A)3/4
B)1/2
C)All
D)1/4
E)2/3
سؤال
The fact that both green and yellow peas were produced by tall pea plants in predictable frequencies  led Mendel to propose the

A)principle of segregation.
B)principle of independent assortment.
C)concept of dominance.
D)concept of codominance.
E)blending theory of inheritance.
سؤال
Two people (both heterozygotes)are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T). The inability to taste PTC is caused by a recessive allele (t). What proportion of their children would be expected to have the tt genotype?

A)3/4
B)1/2
C)All
D)1/4
E)2/3
سؤال
The observed physical manifestation of genes is the

A)genotype.
B)phenotype.
C)phenotypic ratio.
D)genotypic ratio.
E)independent assortment.
سؤال
An individual's actual genetic makeup is called the

A)phenotype.
B)homozygosity.
C)recessiveness.
D)phenotypic ratio.
E)genotype.
سؤال
In Mendel's experiments, the ratio of tall to short plants in the F2 generation was

A)15 to 1.
B)3 to 1.
C)1 to 1.
D)4 to 1.
E)5 to 1.
سؤال
Gregor Mendel

A)published his results and won the Nobel Prize for his discoveries.
B)was trained as a geneticist.
C)died before the importance of his research was recognized.
D)was a professor at the University of Vienna.
E)never published his work.
سؤال
When Mendel crossed true-breeding tall and short parental plants,

A)all the offspring were tall.
B)half the offspring were tall, the other half were short.
C)all the offspring were short.
D)the offspring were intermediate in height relative to the two parent plants.
E)about 90 percent were tall, but the rest were short.
سؤال
Two people (both heterozygotes)are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T). The inability to taste PTC is caused by a recessive allele (t). What proportion of their children would be expected NOT to be able to taste PTC?

A)3/4
B)All
C)1/4
D)2/3
سؤال
When Mendel crossed plants and considered two traits simultaneously (e.g., height and seed color in peas), what proportion of the F2 generation offspring expressed both recessive phenotypes?

A)9/16
B)8/16
C)12/16
D)3/16
E)1/16
سؤال
How do the basic principles of inheritance, identified by Mendel in plants, differ from those in humans?

A)They are simpler.
B)Plants don't have alleles.
C)There are no differences because the basic principles are the same.
D)There are no Mendelian traits in humans.
E)The number of chromosomes is different; therefore, the genetic principles are different.
سؤال
A person who is homozygous recessive at a locus has

A)two copies of the recessive allele.
B)two copies of the dominant allele.
C)an autosomal trisomy.
D)a recessive allele on the X chromosome only.
E)a recessive allele on the Y chromosome only.
سؤال
Dominant alleles

A)usually cause the underproduction of an enzyme.
B)always produce the most desirable phenotype.
C)can mask the expression of other alleles at the same locus.
D)are always the most common allele in a population.
E)were discovered by Charles Darwin.
سؤال
Polygenic traits

A)are discrete.
B)have a continuous range of expression.
C)are controlled by only one genetic locus.
D)include the ABO blood type system and cystic fibrosis.
E)are also called Mendelian traits.
سؤال
Sex-linked traits

A)have their loci on all chromosomes.
B)are expressed more often in females than in males.
C)are expressed in females in the same fashion as autosomal traits.
D)are carried mainly on the Y chromosome.
E)includes albinism.
سؤال
Which of the following is NOT a polygenic trait?

A)Stature
B)Skin color
C)Eye color
D)ABO blood type
E)Hair color
سؤال
A person with blood type B is heterozygous. What is that person's genotype?

A)BB
B)OO
C)BO
D)AB
E)none of these
سؤال
What produces new alleles at a locus?

A)Natural selection
B)Recombination
C)Mutation
D)Migration
E)Genetic drift
سؤال
When a person possesses two different alleles at the same locus, and both alleles are expressed in the phenotype, this is called

A)recessiveness.
B)codominance.
C)dominance.
D)homozygosity.
E)X-linkage.
سؤال
Which gene accounts for 74 percent of the variation in human eye color?

A)MC1R
B)OCA2
C)DELTA23
D)FOXP2
E)HOX
سؤال
Mendelian traits

A)are governed by several genetic loci.
B)are more likely to have identifiable loci than polygenic traits.
C)have continuous distributions.
D)can be described by statistics such as the average and standard deviation.
E)have phenotypic expressions that are often the result of genetic and environmental interactions.
سؤال
Which statement concerning polygenic traits is FALSE?

A)They are governed by more than one genetic locus.
B)Their expression is often influenced by genetic/environmental interactions.
C)They account for most observable phenotypic variation in humans.
D)They are not affected by environmental factors.
E)They are continuous.
سؤال
Evolution can be most succinctly defined as

A)the appearance of new species.
B)the change from one species to another in one generation.
C)a change in allele frequencies from one generation to the next.
D)any type of genetic mutation.
E)genetic drift.
سؤال
In order for a mutation to be passed on to an offspring, the mutation must

A)occur in a gamete.
B)be beneficial.
C)occur in a somatic cell.
D)result in additional chromosomes.
E)be a point mutation only.
سؤال
According to Modern Synthesis, evolution can be defined as a two-stage process that includes

A)genetic drift followed by migration.
B)natural selection followed by migration.
C)recombination followed by mutation.
D)variation followed by natural selection.
E)mutation and gene drift.
سؤال
A man who has type A blood has the AA genotype. His wife, with type B blood, has the BO genotype. Which of the following blood types is/are NOT possible for their children?

A)Type O
B)Type AB
C)Type A
D)Type AO
E)A codominant type
سؤال
Mendelian traits

A)are governed by more than one genetic locus.
B)occur only in some people.
C)are always dominant.
D)are discrete or discontinuous.
E)are always recessive.
سؤال
How many ABO phenotypes are there?

A)4
B)2
C)3
D)6
E)1
سؤال
In a hypothetical situation, B is the allele that causes brachydactyly. If a man who has normal fingers (bb)and a woman with brachydactyly (Bb)have children, what proportion of these children would you expect to have normal fingers? (Hint: Use a Punnett square.)

A)1/16
B)1/8
C)1/4
D)3/4
E)1/2
سؤال
At a hypothetical locus, a man's genotype is Aa. What proportion of his gametes would be expected to receive the A allele?

A)1/3
B)1/2
C)3/4
D)1/4
E)1/8
سؤال
Type AB blood is an example of

A)codominance.
B)blending.
C)recessiveness.
D)dominance.
E)polygenic inheritance.
سؤال
Short-term effects on inherited traits are sometimes called

A)macroevolution.
B)plieotropy.
C)microevolution.
D)speciation.
E)natural selection.
سؤال
Which of the following types of traits are governed by more than one genetic locus?

A)Polygenic
B)Dominant
C)Mendelian
D)Recessive
E)Pleiotropic
سؤال
Polygenic traits account for few, if any, of the readily observable phenotypic variation seen in humans.
سؤال
The only source(s)of new genetic variation in any population is/are

A)mutations.
B)genetic drift.
C)founder effect.
D)migration.
E)natural selection.
سؤال
The majority of sex-linked traits have loci on the X chromosome.
سؤال
Gene flow is defined as the

A)production of new alleles.
B)production of new genetic material.
C)chance loss of alleles in a population.
D)exchange of genes between populations.
E)differential reproductive success of individuals.
سؤال
Many human genetic result from harmful alleles inherited in a Mendelian manner.
سؤال
Achondroplasia is an example of an autosomal recessive trait.
سؤال
Dominance and recessiveness are all-or-nothing situations because the recessive allele has NO phenotypic effects in heterozygotes.
سؤال
Founder effect refers to a type of genetic drift in which allele frequencies are changed in small populations that are taken from larger populations or are left over from the latter.
سؤال
Researchers have identified six different modes of Mendelian inheritance.
سؤال
All variation in mtDNA is caused by mutation.
سؤال
Mendelian traits are more likely to be influenced by environmental factors.
سؤال
The HbS allele increased in frequency in West African populations due to

A)sickle-cell anemia.
B)genetic drift.
C)migration.
D)increased mutation rates.
E)natural selection.
سؤال
Recessive conditions are usually associated with the lack of production of an enzyme.
سؤال
Mendel worked with animal populations to formulate his principles of inheritance.
سؤال
Mendel's first principle of inheritance is independent assortment.
سؤال
Which of the below is FALSE regarding the relationship between malaria and the HbS allele?

A)There is no geographic correlation between the distribution of the HbS allele and malaria.
B)Heterozygotes have greater resistance to malaria than homozygous individuals.
C)The malarial parasite does not reproduce very well in the red blood cells of heterozygotes.
D)Malaria is caused by the Plasmodium parasite.
E)The HbS mutation probably occurs occasionally in all human populations.
سؤال
Allele frequencies are indicators of the genetic makeup of a population, the members of which share a common gene pool.
سؤال
Genetic drift is a result of

A)migrations.
B)an increase in population.
C)genetic diseases.
D)mutations.
E)a small population.
سؤال
Melanin production is a polygenic trait that is influenced by the interactions between several different loci.
سؤال
X-linked traits affect males and females in equal frequencies.
سؤال
Discuss the differences between Mendelian and polygenic modes of inheritance. Provide an example of a Mendelian and a polygenic trait.
سؤال
Explain the role of mutation to evolution, and then using the HbS allele to illustrate, describe why fitness levels are a function of the environment.
سؤال
Explain polygenic inheritance, and give examples of polygenic trains in humans.
سؤال
Explain why a woman with type O blood and a man with type A blood could potentially have children with either type A or O blood.
سؤال
What is the effect of genetic bottlenecks on human and nonhuman species?
سؤال
What are the typical Mendelian phenotypic and genotypic ratios in the F2 generation for a cross of purebred tall and short plants?  Why are these ratios typical?
سؤال
Explain the genetic importance of mitochondrial inheritance.
سؤال
Explain the importance of the discoveries of Gregor Mendel to genetics and include an explanation of each of his principles.
سؤال
Compare and contrast polygenic and Mendelian traits.
سؤال
Describe and explain the factors that produce and redistribute variation.
سؤال
Discuss Modern Synthesis and its importance in bringing together natural selection and mutation as joint forces in biological evolution.
سؤال
Explain the concepts of dominance, codominance, and recessiveness as used in modern genetics.
سؤال
Describe the role of natural selection as directional and its relation to variation. Explain the example of Hb2 and malaria.
سؤال
Describe some environmental factors that can influence genotypes.
سؤال
Explain random assortment.
سؤال
Explain how two parents who do NOT express a particular trait in their phenotype can nevertheless produce children who express the trait. Give an example of a specific trait or disease where this could occur.
سؤال
Explain the importance of mutation as a factor that produces variation and its importance to the evolutionary process.
سؤال
Explain Mendel's principle of segregation.
سؤال
List two evolutionary factors and their level of organization in the evolutionary process.
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ملء الشاشة (f)
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Deck 4: Heredity and Evolution
1
Which is NOT true about random assortment?

A)There is a chance distribution of chromosomes to daughter cells.
B)It is an important source of genetic variation.
C)It produces new alleles.
D)It happens during meiosis.
E)It is important like recombination.
It produces new alleles.
2
A trait is NOT expressed in heterozygotes, it is said to be

A)dominant.
B)codominant.
C)recessive.
D)homozygous dominant.
E)segregated.
recessive.
3
In Mendel's experiments, the tall parental (P)plants

A)were heterozygous for the allele for tallness.
B)were heterozygous at the locus-controlling height.
C)could NOT be crossed with short plants.
D)were homozygous for the allele for shortness.
E)were homozygous for the allele for tallness.
were homozygous for the allele for tallness.
4
Gregor Mendel

A)developed theories of evolutionary change.
B)discovered the structure of the DNA molecule.
C)studied characteristics that are influenced by several genetic loci.
D)discovered the fundamental principles of how traits are inherited.
E)developed the theory of inheritance of acquired characteristics.
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5
Which of the following is NOT inherited in a Mendelian fashion?

A)ABO blood type
B)Marfan syndrome
C)Achondroplasia
D)Phenylketonuria
E)Skin color
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6
The ABO blood type system consists of ______ alleles.

A)6
B)4
C)3
D)2
E)5
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7
Two people (both heterozygotes)are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T). The inability to taste PTC is caused by a recessive allele (t). What proportion of their offspring would be expected to be heterozygous?

A)3/4
B)1/2
C)All
D)1/4
E)2/3
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8
Two people (both heterozygotes)are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T). The inability to taste PTC is caused by a recessive allele (t). What proportion of their children would be expected to have the ability to taste PTC?

A)3/4
B)1/2
C)All
D)1/4
E)2/3
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9
The fact that both green and yellow peas were produced by tall pea plants in predictable frequencies  led Mendel to propose the

A)principle of segregation.
B)principle of independent assortment.
C)concept of dominance.
D)concept of codominance.
E)blending theory of inheritance.
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10
Two people (both heterozygotes)are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T). The inability to taste PTC is caused by a recessive allele (t). What proportion of their children would be expected to have the tt genotype?

A)3/4
B)1/2
C)All
D)1/4
E)2/3
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11
The observed physical manifestation of genes is the

A)genotype.
B)phenotype.
C)phenotypic ratio.
D)genotypic ratio.
E)independent assortment.
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12
An individual's actual genetic makeup is called the

A)phenotype.
B)homozygosity.
C)recessiveness.
D)phenotypic ratio.
E)genotype.
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13
In Mendel's experiments, the ratio of tall to short plants in the F2 generation was

A)15 to 1.
B)3 to 1.
C)1 to 1.
D)4 to 1.
E)5 to 1.
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14
Gregor Mendel

A)published his results and won the Nobel Prize for his discoveries.
B)was trained as a geneticist.
C)died before the importance of his research was recognized.
D)was a professor at the University of Vienna.
E)never published his work.
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15
When Mendel crossed true-breeding tall and short parental plants,

A)all the offspring were tall.
B)half the offspring were tall, the other half were short.
C)all the offspring were short.
D)the offspring were intermediate in height relative to the two parent plants.
E)about 90 percent were tall, but the rest were short.
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16
Two people (both heterozygotes)are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T). The inability to taste PTC is caused by a recessive allele (t). What proportion of their children would be expected NOT to be able to taste PTC?

A)3/4
B)All
C)1/4
D)2/3
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17
When Mendel crossed plants and considered two traits simultaneously (e.g., height and seed color in peas), what proportion of the F2 generation offspring expressed both recessive phenotypes?

A)9/16
B)8/16
C)12/16
D)3/16
E)1/16
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18
How do the basic principles of inheritance, identified by Mendel in plants, differ from those in humans?

A)They are simpler.
B)Plants don't have alleles.
C)There are no differences because the basic principles are the same.
D)There are no Mendelian traits in humans.
E)The number of chromosomes is different; therefore, the genetic principles are different.
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19
A person who is homozygous recessive at a locus has

A)two copies of the recessive allele.
B)two copies of the dominant allele.
C)an autosomal trisomy.
D)a recessive allele on the X chromosome only.
E)a recessive allele on the Y chromosome only.
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20
Dominant alleles

A)usually cause the underproduction of an enzyme.
B)always produce the most desirable phenotype.
C)can mask the expression of other alleles at the same locus.
D)are always the most common allele in a population.
E)were discovered by Charles Darwin.
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21
Polygenic traits

A)are discrete.
B)have a continuous range of expression.
C)are controlled by only one genetic locus.
D)include the ABO blood type system and cystic fibrosis.
E)are also called Mendelian traits.
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22
Sex-linked traits

A)have their loci on all chromosomes.
B)are expressed more often in females than in males.
C)are expressed in females in the same fashion as autosomal traits.
D)are carried mainly on the Y chromosome.
E)includes albinism.
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23
Which of the following is NOT a polygenic trait?

A)Stature
B)Skin color
C)Eye color
D)ABO blood type
E)Hair color
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24
A person with blood type B is heterozygous. What is that person's genotype?

A)BB
B)OO
C)BO
D)AB
E)none of these
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25
What produces new alleles at a locus?

A)Natural selection
B)Recombination
C)Mutation
D)Migration
E)Genetic drift
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26
When a person possesses two different alleles at the same locus, and both alleles are expressed in the phenotype, this is called

A)recessiveness.
B)codominance.
C)dominance.
D)homozygosity.
E)X-linkage.
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27
Which gene accounts for 74 percent of the variation in human eye color?

A)MC1R
B)OCA2
C)DELTA23
D)FOXP2
E)HOX
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28
Mendelian traits

A)are governed by several genetic loci.
B)are more likely to have identifiable loci than polygenic traits.
C)have continuous distributions.
D)can be described by statistics such as the average and standard deviation.
E)have phenotypic expressions that are often the result of genetic and environmental interactions.
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29
Which statement concerning polygenic traits is FALSE?

A)They are governed by more than one genetic locus.
B)Their expression is often influenced by genetic/environmental interactions.
C)They account for most observable phenotypic variation in humans.
D)They are not affected by environmental factors.
E)They are continuous.
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30
Evolution can be most succinctly defined as

A)the appearance of new species.
B)the change from one species to another in one generation.
C)a change in allele frequencies from one generation to the next.
D)any type of genetic mutation.
E)genetic drift.
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31
In order for a mutation to be passed on to an offspring, the mutation must

A)occur in a gamete.
B)be beneficial.
C)occur in a somatic cell.
D)result in additional chromosomes.
E)be a point mutation only.
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32
According to Modern Synthesis, evolution can be defined as a two-stage process that includes

A)genetic drift followed by migration.
B)natural selection followed by migration.
C)recombination followed by mutation.
D)variation followed by natural selection.
E)mutation and gene drift.
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33
A man who has type A blood has the AA genotype. His wife, with type B blood, has the BO genotype. Which of the following blood types is/are NOT possible for their children?

A)Type O
B)Type AB
C)Type A
D)Type AO
E)A codominant type
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34
Mendelian traits

A)are governed by more than one genetic locus.
B)occur only in some people.
C)are always dominant.
D)are discrete or discontinuous.
E)are always recessive.
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35
How many ABO phenotypes are there?

A)4
B)2
C)3
D)6
E)1
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36
In a hypothetical situation, B is the allele that causes brachydactyly. If a man who has normal fingers (bb)and a woman with brachydactyly (Bb)have children, what proportion of these children would you expect to have normal fingers? (Hint: Use a Punnett square.)

A)1/16
B)1/8
C)1/4
D)3/4
E)1/2
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37
At a hypothetical locus, a man's genotype is Aa. What proportion of his gametes would be expected to receive the A allele?

A)1/3
B)1/2
C)3/4
D)1/4
E)1/8
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38
Type AB blood is an example of

A)codominance.
B)blending.
C)recessiveness.
D)dominance.
E)polygenic inheritance.
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39
Short-term effects on inherited traits are sometimes called

A)macroevolution.
B)plieotropy.
C)microevolution.
D)speciation.
E)natural selection.
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40
Which of the following types of traits are governed by more than one genetic locus?

A)Polygenic
B)Dominant
C)Mendelian
D)Recessive
E)Pleiotropic
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41
Polygenic traits account for few, if any, of the readily observable phenotypic variation seen in humans.
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42
The only source(s)of new genetic variation in any population is/are

A)mutations.
B)genetic drift.
C)founder effect.
D)migration.
E)natural selection.
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43
The majority of sex-linked traits have loci on the X chromosome.
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44
Gene flow is defined as the

A)production of new alleles.
B)production of new genetic material.
C)chance loss of alleles in a population.
D)exchange of genes between populations.
E)differential reproductive success of individuals.
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45
Many human genetic result from harmful alleles inherited in a Mendelian manner.
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46
Achondroplasia is an example of an autosomal recessive trait.
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47
Dominance and recessiveness are all-or-nothing situations because the recessive allele has NO phenotypic effects in heterozygotes.
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48
Founder effect refers to a type of genetic drift in which allele frequencies are changed in small populations that are taken from larger populations or are left over from the latter.
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49
Researchers have identified six different modes of Mendelian inheritance.
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50
All variation in mtDNA is caused by mutation.
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51
Mendelian traits are more likely to be influenced by environmental factors.
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52
The HbS allele increased in frequency in West African populations due to

A)sickle-cell anemia.
B)genetic drift.
C)migration.
D)increased mutation rates.
E)natural selection.
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53
Recessive conditions are usually associated with the lack of production of an enzyme.
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54
Mendel worked with animal populations to formulate his principles of inheritance.
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55
Mendel's first principle of inheritance is independent assortment.
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56
Which of the below is FALSE regarding the relationship between malaria and the HbS allele?

A)There is no geographic correlation between the distribution of the HbS allele and malaria.
B)Heterozygotes have greater resistance to malaria than homozygous individuals.
C)The malarial parasite does not reproduce very well in the red blood cells of heterozygotes.
D)Malaria is caused by the Plasmodium parasite.
E)The HbS mutation probably occurs occasionally in all human populations.
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57
Allele frequencies are indicators of the genetic makeup of a population, the members of which share a common gene pool.
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58
Genetic drift is a result of

A)migrations.
B)an increase in population.
C)genetic diseases.
D)mutations.
E)a small population.
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59
Melanin production is a polygenic trait that is influenced by the interactions between several different loci.
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60
X-linked traits affect males and females in equal frequencies.
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61
Discuss the differences between Mendelian and polygenic modes of inheritance. Provide an example of a Mendelian and a polygenic trait.
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62
Explain the role of mutation to evolution, and then using the HbS allele to illustrate, describe why fitness levels are a function of the environment.
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63
Explain polygenic inheritance, and give examples of polygenic trains in humans.
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64
Explain why a woman with type O blood and a man with type A blood could potentially have children with either type A or O blood.
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65
What is the effect of genetic bottlenecks on human and nonhuman species?
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66
What are the typical Mendelian phenotypic and genotypic ratios in the F2 generation for a cross of purebred tall and short plants?  Why are these ratios typical?
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67
Explain the genetic importance of mitochondrial inheritance.
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68
Explain the importance of the discoveries of Gregor Mendel to genetics and include an explanation of each of his principles.
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69
Compare and contrast polygenic and Mendelian traits.
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70
Describe and explain the factors that produce and redistribute variation.
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71
Discuss Modern Synthesis and its importance in bringing together natural selection and mutation as joint forces in biological evolution.
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72
Explain the concepts of dominance, codominance, and recessiveness as used in modern genetics.
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73
Describe the role of natural selection as directional and its relation to variation. Explain the example of Hb2 and malaria.
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74
Describe some environmental factors that can influence genotypes.
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75
Explain random assortment.
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76
Explain how two parents who do NOT express a particular trait in their phenotype can nevertheless produce children who express the trait. Give an example of a specific trait or disease where this could occur.
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77
Explain the importance of mutation as a factor that produces variation and its importance to the evolutionary process.
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78
Explain Mendel's principle of segregation.
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79
List two evolutionary factors and their level of organization in the evolutionary process.
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