Deck 39: Information Flow and the Neuron

ملء الشاشة (f)
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سؤال
In the context of the nervous system, what does the term "nucleus" mean? ​

A)a cluster of EPSPs converging on an axonal hillock
B)a cluster of IPSPs converging on an axonal hillock
C)a cluster of axon terminals converging on a single neuron
D)a cluster of dendrites centralized on a single neuron
E)a cluster of neurons in the central nervous system with a related function
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سؤال
Where is a ganglion found? ​

A)brain
B)spinal cord
C)peripheral nervous system
D)brain stem
E)interneurons
سؤال
Which category of organic macromolecule allows myelinated sheaths to act as electrical insulators? ​

A)proteins
B)carbohydrates
C)lipids
D)RNA
E)DNA
سؤال
Otto Loewi demonstrated that neurons transmit signals across synapses by ____. ​

A)electrical signals
B)calcium channels
C)acetylcholine
D)chemical signals
E)proteins
سؤال
In humans and some primates, the most abundant neurons are the ____. ​

A)efferent neurons
B)afferent neurons
C)interneurons
D)motor neurons
E)sensory neurons
سؤال
Which cells assist and nourish neurons that transmit electrical signals? ​

A)receptor cells
B)neurons
C)effector cells
D)glial cells
E)signal cells
سؤال
Which cells serve as electrical insulators in the central nervous system? ​

A)Schwann cells
B)oligodendrocytes
C)astrocytes
D)efferent neurons
E)afferent neurons
سؤال
Which part of the neuron conducts the electrical signals away from the cell body of a neuron?

A)axon terminal
B)axon
C)axon hillock
D)nucleus
E)dendrites
سؤال
Electrical synapses are most common in the ____. ​

A)cortex
B)spinal cord
C)digestive tract
D)retina
E)ear
سؤال
If a drug inhibits the uptake of an excitatory neurotransmitter after it has been released into the synaptic cleft, what is the most likely result? ​

A)an increased number of IPSPs
B)an increased number of EPSPs
C)a prolonged hyperpolarization
D)a decreased number of IPSPs
E)a decreased number of EPSPs
سؤال
A trapeze artist loses her grip and falls off the trapeze, causing her heart rate to increase in response to the fear of falling (despite the net below to prevent injury). Which type of neurons is directly responsible for this increase in heart rate? ​

A)afferent neuron
B)efferent neuron
C)interneuron
D)motor neuron
E)Schwann cells
سؤال
If a drug binds to a receptor, which normally triggers the opening of a Na+ channel, causing it to open in the absence of neurotransmitter release, what is the most likely result? ​

A)an increased number of IPSPs
B)an increased number of EPSPs
C)a prolonged hyperpolarization
D)a decreased number of IPSPs
E)a decreased number of EPSPs
سؤال
Which glial cell(s)is/are only found in the peripheral nervous system? ​

A)Schwann cells
B)oligodendrocytes
C)astrocytes
D)microglia
E)saltatory cells
سؤال
Cells in the nervous system that send and receive electrical signals are called ____. ​

A)receptors
B)neurons
C)sensors
D)glial cells
E)signal cells
سؤال
If a drug binds irreversibly to a postsynaptic receptor to prevent the binding of an excitatory neurotransmitter, what is the most likely result? ​

A)an increased number of IPSPs
B)an increased number of EPSPs
C)a prolonged hyperpolarization
D)a decreased number of IPSPs
E)a decreased number of EPSPs
سؤال
Which type of neuron directly stimulates a muscle or gland? ​

A)​afferent neurons only
B)efferent neurons only ​
C)interneurons
D)afferent and efferent neurons
E)afferent neurons and interneurons
سؤال
Which component of a neural signaling pathway sorts and interprets messages? ​

A)response
B)integration
C)transmission
D)reception
E)action
سؤال
Which process is responsible for the release of neurotransmitters from the presynaptic neuron into the synapse? ​

A)diffusion
B)endocytosis ​
C)exocytosis
D)fusion
E)synaptic release
سؤال
Which sequence of the neural signaling pathway is correctly arranged from the earliest to the latest event as it occurs in the nervous system? ​

A)integration, transmission, reception, response, transmission
B)transmission, response, reception, transmission, integration
C)response, reception, transmission, integration, transmission
D)reception, transmission, integration, transmission, response
E)transmission, integration, transmission, reception, response
سؤال
A frog sees a fly and immediately sticks his tongue out to catch it. Which type of cell transmitted the visual signal from his eye to his brain? ​

A)afferent neuron
B)efferent neuron
C)interneuron
D)motor neuron
E)Schwann cell
سؤال
Answer the question using the accompanying figure. At which point in this action potential diagram does the onset of Na+ channel inactivation stop the inward flow of Na+? ​

A)​A
B)​B
C)​C
D)​D
E)​E
سؤال
The Nernst equation is used to calculate the ____.

A)action potential
B)equilibrium potential
C)membrane potential of a neuron at rest c
D)membrane potential of a hyperpolarized neuron
E)membrane potential of a depolarized neuron
سؤال
As the action potential peaks, ____. ​

A)the activation gates of Na+ channels close
B)the inactivation gates of Na+ channels close
C)the activation gates of K+ channels close
D)the inactivation gates of Na+ channels close
E)Na+/K+ active transport pumps are activated
سؤال
In an effort to determine the mechanism of neuronal signaling, Otto Loewi isolated ____.

A)frog hearts
B)frog brains
C)rat hearts
D)rat brains
E)rat vagus nerve
سؤال
When measuring membrane potential, the tip of a microelectrode is inserted into a(n)____. ​

A)axon
B)node of Ranvier
C)Schwann cell
D)dendrite
E)glial cell
سؤال
Depolarization of the neuronal plasma membrane occurs due to ____. ​

A)the diffusion of K+ into the cell
B)the diffusion of K+ out of the cell
C)the diffusion of Na+ into the cell. ​
D)the diffusion of Na+ out of the cell
E)closed gated channels
سؤال
When a neuron membrane potential becomes less negative, it is said to be ____. ​

A)depolarized
B)hyperpolarized
C)repolarized
D)damaged
E)activated above the threshold potential
سؤال
An abrupt and transient change in membrane potential is called a(n)____.

A)electrical potential
B)refractory potential
C)threshold potential
D)resting potential
E)action potential
سؤال
Answer the question using the accompanying figure. At which point in this action potential diagram are many Na+ activation gates open and K+ activation gates closed?

A)A
B)B
C)?C
D)?D
E)?E
سؤال
<strong>    ​  Figure 39.1 Answer the question using the accompanying figure. At which point in this action potential diagram are Na<sup>+</sup> inactivation gates opening?</strong> A)​A B)​B C)​C D)​D E)​E <div style=padding-top: 35px>  
​  Figure 39.1
Answer the question using the accompanying figure. At which point in this action potential diagram are Na+ inactivation gates opening?

A)​A
B)​B
C)​C
D)​D
E)​E
سؤال
The minimum level of depolarization required to initiate an action potential in an excitable cell is called the ____ potential. ​

A)electrical
B)refractory
C)membrane
D)resting
E)threshold
سؤال
When threshold potential is reached, ____. ​

A)the activation gates of Na+ channels open
B)the inactivation gates of Na+ channels open
C)the activation gates of K+ channels open
D)the inactivation gates of Na+ channels open
E)Na+/K+ active transport pumps are activated
سؤال
Calculate ENa for a neuron that has an extracellular concentration of Na+ of 78 mM and an intracellular concentration of Na+ of 6 mM. ​

A)- 68.0 mV
B)- 1.14 mV
C)1.14 mV
D)31.6 mV
E)68.0 mV
سؤال
What is the typical resting potential of an isolated neuron? ​

A)- 60 mV
B)- 70 mV
C)- 80 mV
D)- 90 mV
E)100 mV
سؤال
If the K+ channels of an excitable plasma membrane were blocked by the action of a drug, which process(es)would be disrupted? ​

A)repolarization
B)depolarization
C)hyperpolarization
D)repolarization and depolarization
E)repolarization and hyperpolarization
سؤال
When a neuron membrane potential goes below its resting value it becomes ____. ​

A)depolarized
B)hyperpolarized
C)repolarized
D)damaged
E)re-stimulated
سؤال
Answer the question using the accompanying figure. At which point in this action potential diagram does the K+channel close to stabilize the membrane potential?

A)?A
B)?B
C)?C
D)?D
E)?E
سؤال
The refractory period of a neuronal plasma membrane is important because it ____. ​

A)establishes the resting potential
B)initiates an action potential
C)ensures that the threshold potential will be reached
D)ensures that an impulse will travel in a one-way direction
E)resets the threshold potential
سؤال
For a neuron at rest, there is a higher concentration of ____ outside the cell than inside.

A)Na+
B)K+
C)Ca2+
D)anions
E)ATP
سؤال
During an action potential, the membrane potential can reach as high as ____. ​

A)- 10 mV
B)0 mV
C)+10 mV
D)+20 mV
E)+30 mV
سؤال
The spaces between adjacent Schwann cells are called ____. ​

A)nodes of Ranvier
B)axon terminals
C)dendrites
D)intercalated discs
E)active gaps
سؤال
When a fist clenches to grasp a pencil, which neurotransmitter is most likely involved?

A)norepinephrine
B)serotonin
C)dopamine
D)acetylcholine
E)glutamate
سؤال
The intensity of an electrical impulse is reflected in the ____ of action potentials. ​

A)frequency
B)magnitude
C)duration
D)intensity
E)the frequency and duration
سؤال
What removes Ca2+ from the inside of an axon terminal of a chemical synapse after an electrical impulse has passed? ​

A)ion channels
B)active transport pumps
C)passive carrier proteins
D)exocytosis
E)simple diffusion through the plasma membrane
سؤال
What will be the effect of a drug that prevents the release of intracellular calcium? ​

A)a decreased number of IPSPs
B)a decreased number of EPSPs
C)a prolonged hyperpolarization
D)increased neurotransmitter release
E)decreased neurotransmitter release
سؤال
An action potential is propagated down an unmyelinated neuronal plasma membrane because it stimulates voltage-gated ____ channels adjacent to it. (Choose the most accurate answer.)​

A)Na+
B)Ca2+
C)K+
D)Na+ and Ca2+
E)K+ and Ca2+
سؤال
The binding of a neurotransmitter to ligand-gated K+ channels will cause ____ in the postsynaptic membrane. ​

A)depolarization only
B)hyperpolarization
C)repolarization only
D)apolarization
E)depolarization and repolarization
سؤال
In vertebrates, the neurotransmitter acetylcholine ____. ​

A)can act as a direct neurotransmitter between neurons and muscle cells
B)is involved in memory and learning
C)can be released into the circulation and act as a hormone
D)can act as a pain reducer and initiate euphoria
E)is involved in pain perception
سؤال
The duration of an action potential is approximately five ____.

A)microseconds
B)milliseconds
C)centiseconds
D)seconds
E)nanoseconds
سؤال
Action potentials are propagated in a one-way direction down a neuronal plasma membrane because ____. ​

A)the action potential is of insufficient intensity to stimulate the voltage-gated ion channels behind it
B)the adjacent channels upstream from the action potential are ligand-gated
C)the adjacent channels upstream from the action potential are in a refractory period
D)voltage-gated ion channels are suppressed
E)the adjacent channels upstream from the action potential are at their threshold potential
سؤال
The magnitude of an action potential ____ as it is propagated down an excitable membrane due to the ____ principle. ​

A)increases; all-or-nothing principle
B)remains constant; all-or-nothing principle
C)increases; threshold principle
D)remains constant; threshold principle
سؤال
Which neurotransmitter is most likely to be inhibitory? ​

A)glutamate
B)dopamine
C)Substance P
D)GABA
E)acetylcholine
سؤال
The binding of a neurotransmitter to ligand-gated Na+ channels will cause ____ in the postsynaptic membrane. ​

A)depolarization only
B)hyperpolarization
C)repolarization only
D)apolarization
E)depolarization and repolarization
سؤال
Neuropeptide neurotransmitters ____. ​

A)can act as direct neurotransmitters between neurons and muscle cells
B)can act as postsynaptic membrane inhibitors
C)directly open K+ channels to inhibit neurons
D)can act as pain reducers and initiate euphoria
E)directly inhibit euphoria
سؤال
When an action potential reaches the axon terminal, the ____ channels are activated to trigger synaptic vesicle release. ​

A)voltage-gated Cl- channels
B)voltage-gated Ca2+ channels
C)voltage-gated Na+ channels
D)ligand-gated Cl- channels
E)ligand-gated Ca2+ channels
سؤال
Action potential propagation is the fastest in ____. ​

A)a myelinated axon with a small diameter
B)an unmyelinated axon with a small diameter
C)a myelinated axon with a large diameter
D)an unmyelinated axon with a large diameter
E)all myelinated axons regardless of diameter
سؤال
Place the events in chemical synapse transmission in the correct order.
​1.Ca2+ enters axon terminal.
2. Ligand-gated ion channels open in postsynaptic membrane.
3.Neurotransmitter binds to postsynaptic receptor.
4.Action potential reaches axon terminal of presynaptic neuron.
5.Neurotransmitter released by exocytosis.

A)4, 1, 5, 3, 2
B)4, 3, 1, 5, 2
C)4, 5, 1, 3, 2
D)4, 1, 3, 5, 2
E)4, 5, 2, 3, 1
سؤال
The binding of a neurotransmitter to ligand-gated Cl - channels will cause ____ in the postsynaptic membrane. ​

A)depolarization only
B)hyperpolarization
C)repolarization only
D)apolarization
E)depolarization and repolarization
سؤال
Jean-Luc Eiselé and his coworkers used ______ receptors in their research on neurotransmitter receptor function. ​

A)African clawed frog
B)toad
C)artificial
D)dog
E)human
سؤال
The neurotransmitter receptor research of Jean-Luc Eiselé and his coworkers showed that ____. ​

A)neurotransmitters are dependent on the activity of Na+
B)neurotransmitters are dependent on the activity of K+
C)neurotransmitters are dependent on the activity of Cl
D)neurotransmitters are dependent on the activity of Ca+
E)the parts of a receptor binding a neurotransmitter and conducting ions function independently
سؤال
Match between columns
occurs when a membrane potential becomes more negative than its resting membrane potential
depolarization
occurs when a membrane potential becomes more negative than its resting membrane potential
repolarization
occurs when a membrane potential becomes more negative than its resting membrane potential
hyperpolarization
سؤال
Match between columns
describes the change in resting membrane potential that causes it to approach threshold potential
depolarization
describes the change in resting membrane potential that causes it to approach threshold potential
repolarization
describes the change in resting membrane potential that causes it to approach threshold potential
hyperpolarization
سؤال
Match between columns
begins when Na + channel inactivation gates close and K + activation gates open
depolarization
begins when Na + channel inactivation gates close and K + activation gates open
repolarization
begins when Na + channel inactivation gates close and K + activation gates open
hyperpolarization
سؤال
At which neuronal structure does summation occur? ​

A)dendrites
B)cell body
C)axon hillock
D)Schwann cells
E)axon terminals
سؤال
To which class of neurotransmitters does dopamine belong? ​

A)acetylcholine
B)monoamines
C)amino acids
D)neuropeptides
E)gaseous neurotransmitters
سؤال
Match between columns
the phase of an action potential when the membrane potential becomes more positive
depolarization
the phase of an action potential when the membrane potential becomes more positive
repolarization
the phase of an action potential when the membrane potential becomes more positive
hyperpolarization
سؤال
Match between columns
occurs in a postsynaptic membrane when ligand-gated Na+ channels open
depolarization
occurs in a postsynaptic membrane when ligand-gated Na+ channels open
repolarization
occurs in a postsynaptic membrane when ligand-gated Na+ channels open
hyperpolarization
سؤال
A graded, subthreshold change in the postsynaptic membrane potential that moves it toward threshold is called a(n)____. ​

A)IPSP
B)hyperpolarization
C)EPSP
D)depolarization
E)repolarization
سؤال
Approximately how many neurons comprise the human brain?

A)1,000
B)50,000
C)100,000
D)75,000,000
E)86,000,000,000
سؤال
Despite recent advances, ___ is/are needed to revolutionize the field of neuroscience and allow for better understanding of neural networking

A)genomics
B)proteomics
C)computational simulations
D)genetic engineering
E)enhanced microscopic techniques
سؤال
Which neuronal structure has the greatest density of voltage-gated Na+ channels, resulting in the lowest threshold potential along a neuron? ​

A)dendrites
B)cell body
C)axon hillock
D)axon
E)axon terminals
سؤال
Assume a neuron receives EPSPs and IPSPs from several adjacent neurons. How might that neuron's threshold potential be reached, causing it to produce its own action potential?

A)if IPSPs outnumber EPSPs
B)if IPSPs equal EPSPs
C)if EPSPs outnumber IPSPs
D)if the adjacent neurons contain many axon terminals
E)if the receiving neuron contains many dendrites
سؤال
Match between columns
causes a neuron membrane potential to become more negative, allowing it to approach its resting potential
depolarization
causes a neuron membrane potential to become more negative, allowing it to approach its resting potential
repolarization
causes a neuron membrane potential to become more negative, allowing it to approach its resting potential
hyperpolarization
سؤال
Match between columns
occurs due to the diffusion of Na +
depolarization
occurs due to the diffusion of Na +
repolarization
occurs due to the diffusion of Na +
hyperpolarization
سؤال
Match between columns
occurs in a postsynaptic membrane when ligand-gated Cl - channels open
depolarization
occurs in a postsynaptic membrane when ligand-gated Cl - channels open
repolarization
occurs in a postsynaptic membrane when ligand-gated Cl - channels open
hyperpolarization
سؤال
Match between columns
an EPSP, for example
depolarization
an EPSP, for example
repolarization
an EPSP, for example
hyperpolarization
سؤال
To which class of neurotransmitters does glutamate belong?

A)acetylcholine
B)monoamines
C)amino acids
D)neuropeptides
E)gaseous neurotransmitters
سؤال
Match between columns
an IPSP, for example
depolarization
an IPSP, for example
repolarization
an IPSP, for example
hyperpolarization
سؤال
To which class of neurotransmitters does substance P belong?

A)acetylcholine
B)monoamines
C)amino acids
D)neuropeptides
E)gaseous neurotransmitters
سؤال
After burning your hand on a hot burner, which neurotransmitter will most likely be released from the pain receptors? ​

A)glutamate
B)dopamine
C)substance P
D)GABA
E)acetylcholine
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ملء الشاشة (f)
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Deck 39: Information Flow and the Neuron
1
In the context of the nervous system, what does the term "nucleus" mean? ​

A)a cluster of EPSPs converging on an axonal hillock
B)a cluster of IPSPs converging on an axonal hillock
C)a cluster of axon terminals converging on a single neuron
D)a cluster of dendrites centralized on a single neuron
E)a cluster of neurons in the central nervous system with a related function
E
2
Where is a ganglion found? ​

A)brain
B)spinal cord
C)peripheral nervous system
D)brain stem
E)interneurons
C
3
Which category of organic macromolecule allows myelinated sheaths to act as electrical insulators? ​

A)proteins
B)carbohydrates
C)lipids
D)RNA
E)DNA
C
4
Otto Loewi demonstrated that neurons transmit signals across synapses by ____. ​

A)electrical signals
B)calcium channels
C)acetylcholine
D)chemical signals
E)proteins
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5
In humans and some primates, the most abundant neurons are the ____. ​

A)efferent neurons
B)afferent neurons
C)interneurons
D)motor neurons
E)sensory neurons
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6
Which cells assist and nourish neurons that transmit electrical signals? ​

A)receptor cells
B)neurons
C)effector cells
D)glial cells
E)signal cells
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7
Which cells serve as electrical insulators in the central nervous system? ​

A)Schwann cells
B)oligodendrocytes
C)astrocytes
D)efferent neurons
E)afferent neurons
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8
Which part of the neuron conducts the electrical signals away from the cell body of a neuron?

A)axon terminal
B)axon
C)axon hillock
D)nucleus
E)dendrites
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9
Electrical synapses are most common in the ____. ​

A)cortex
B)spinal cord
C)digestive tract
D)retina
E)ear
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10
If a drug inhibits the uptake of an excitatory neurotransmitter after it has been released into the synaptic cleft, what is the most likely result? ​

A)an increased number of IPSPs
B)an increased number of EPSPs
C)a prolonged hyperpolarization
D)a decreased number of IPSPs
E)a decreased number of EPSPs
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11
A trapeze artist loses her grip and falls off the trapeze, causing her heart rate to increase in response to the fear of falling (despite the net below to prevent injury). Which type of neurons is directly responsible for this increase in heart rate? ​

A)afferent neuron
B)efferent neuron
C)interneuron
D)motor neuron
E)Schwann cells
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12
If a drug binds to a receptor, which normally triggers the opening of a Na+ channel, causing it to open in the absence of neurotransmitter release, what is the most likely result? ​

A)an increased number of IPSPs
B)an increased number of EPSPs
C)a prolonged hyperpolarization
D)a decreased number of IPSPs
E)a decreased number of EPSPs
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13
Which glial cell(s)is/are only found in the peripheral nervous system? ​

A)Schwann cells
B)oligodendrocytes
C)astrocytes
D)microglia
E)saltatory cells
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14
Cells in the nervous system that send and receive electrical signals are called ____. ​

A)receptors
B)neurons
C)sensors
D)glial cells
E)signal cells
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15
If a drug binds irreversibly to a postsynaptic receptor to prevent the binding of an excitatory neurotransmitter, what is the most likely result? ​

A)an increased number of IPSPs
B)an increased number of EPSPs
C)a prolonged hyperpolarization
D)a decreased number of IPSPs
E)a decreased number of EPSPs
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16
Which type of neuron directly stimulates a muscle or gland? ​

A)​afferent neurons only
B)efferent neurons only ​
C)interneurons
D)afferent and efferent neurons
E)afferent neurons and interneurons
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17
Which component of a neural signaling pathway sorts and interprets messages? ​

A)response
B)integration
C)transmission
D)reception
E)action
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18
Which process is responsible for the release of neurotransmitters from the presynaptic neuron into the synapse? ​

A)diffusion
B)endocytosis ​
C)exocytosis
D)fusion
E)synaptic release
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19
Which sequence of the neural signaling pathway is correctly arranged from the earliest to the latest event as it occurs in the nervous system? ​

A)integration, transmission, reception, response, transmission
B)transmission, response, reception, transmission, integration
C)response, reception, transmission, integration, transmission
D)reception, transmission, integration, transmission, response
E)transmission, integration, transmission, reception, response
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20
A frog sees a fly and immediately sticks his tongue out to catch it. Which type of cell transmitted the visual signal from his eye to his brain? ​

A)afferent neuron
B)efferent neuron
C)interneuron
D)motor neuron
E)Schwann cell
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21
Answer the question using the accompanying figure. At which point in this action potential diagram does the onset of Na+ channel inactivation stop the inward flow of Na+? ​

A)​A
B)​B
C)​C
D)​D
E)​E
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22
The Nernst equation is used to calculate the ____.

A)action potential
B)equilibrium potential
C)membrane potential of a neuron at rest c
D)membrane potential of a hyperpolarized neuron
E)membrane potential of a depolarized neuron
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23
As the action potential peaks, ____. ​

A)the activation gates of Na+ channels close
B)the inactivation gates of Na+ channels close
C)the activation gates of K+ channels close
D)the inactivation gates of Na+ channels close
E)Na+/K+ active transport pumps are activated
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24
In an effort to determine the mechanism of neuronal signaling, Otto Loewi isolated ____.

A)frog hearts
B)frog brains
C)rat hearts
D)rat brains
E)rat vagus nerve
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25
When measuring membrane potential, the tip of a microelectrode is inserted into a(n)____. ​

A)axon
B)node of Ranvier
C)Schwann cell
D)dendrite
E)glial cell
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26
Depolarization of the neuronal plasma membrane occurs due to ____. ​

A)the diffusion of K+ into the cell
B)the diffusion of K+ out of the cell
C)the diffusion of Na+ into the cell. ​
D)the diffusion of Na+ out of the cell
E)closed gated channels
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27
When a neuron membrane potential becomes less negative, it is said to be ____. ​

A)depolarized
B)hyperpolarized
C)repolarized
D)damaged
E)activated above the threshold potential
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28
An abrupt and transient change in membrane potential is called a(n)____.

A)electrical potential
B)refractory potential
C)threshold potential
D)resting potential
E)action potential
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29
Answer the question using the accompanying figure. At which point in this action potential diagram are many Na+ activation gates open and K+ activation gates closed?

A)A
B)B
C)?C
D)?D
E)?E
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30
<strong>    ​  Figure 39.1 Answer the question using the accompanying figure. At which point in this action potential diagram are Na<sup>+</sup> inactivation gates opening?</strong> A)​A B)​B C)​C D)​D E)​E  
​  Figure 39.1
Answer the question using the accompanying figure. At which point in this action potential diagram are Na+ inactivation gates opening?

A)​A
B)​B
C)​C
D)​D
E)​E
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31
The minimum level of depolarization required to initiate an action potential in an excitable cell is called the ____ potential. ​

A)electrical
B)refractory
C)membrane
D)resting
E)threshold
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32
When threshold potential is reached, ____. ​

A)the activation gates of Na+ channels open
B)the inactivation gates of Na+ channels open
C)the activation gates of K+ channels open
D)the inactivation gates of Na+ channels open
E)Na+/K+ active transport pumps are activated
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33
Calculate ENa for a neuron that has an extracellular concentration of Na+ of 78 mM and an intracellular concentration of Na+ of 6 mM. ​

A)- 68.0 mV
B)- 1.14 mV
C)1.14 mV
D)31.6 mV
E)68.0 mV
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34
What is the typical resting potential of an isolated neuron? ​

A)- 60 mV
B)- 70 mV
C)- 80 mV
D)- 90 mV
E)100 mV
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35
If the K+ channels of an excitable plasma membrane were blocked by the action of a drug, which process(es)would be disrupted? ​

A)repolarization
B)depolarization
C)hyperpolarization
D)repolarization and depolarization
E)repolarization and hyperpolarization
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36
When a neuron membrane potential goes below its resting value it becomes ____. ​

A)depolarized
B)hyperpolarized
C)repolarized
D)damaged
E)re-stimulated
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37
Answer the question using the accompanying figure. At which point in this action potential diagram does the K+channel close to stabilize the membrane potential?

A)?A
B)?B
C)?C
D)?D
E)?E
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38
The refractory period of a neuronal plasma membrane is important because it ____. ​

A)establishes the resting potential
B)initiates an action potential
C)ensures that the threshold potential will be reached
D)ensures that an impulse will travel in a one-way direction
E)resets the threshold potential
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39
For a neuron at rest, there is a higher concentration of ____ outside the cell than inside.

A)Na+
B)K+
C)Ca2+
D)anions
E)ATP
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40
During an action potential, the membrane potential can reach as high as ____. ​

A)- 10 mV
B)0 mV
C)+10 mV
D)+20 mV
E)+30 mV
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41
The spaces between adjacent Schwann cells are called ____. ​

A)nodes of Ranvier
B)axon terminals
C)dendrites
D)intercalated discs
E)active gaps
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42
When a fist clenches to grasp a pencil, which neurotransmitter is most likely involved?

A)norepinephrine
B)serotonin
C)dopamine
D)acetylcholine
E)glutamate
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43
The intensity of an electrical impulse is reflected in the ____ of action potentials. ​

A)frequency
B)magnitude
C)duration
D)intensity
E)the frequency and duration
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44
What removes Ca2+ from the inside of an axon terminal of a chemical synapse after an electrical impulse has passed? ​

A)ion channels
B)active transport pumps
C)passive carrier proteins
D)exocytosis
E)simple diffusion through the plasma membrane
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45
What will be the effect of a drug that prevents the release of intracellular calcium? ​

A)a decreased number of IPSPs
B)a decreased number of EPSPs
C)a prolonged hyperpolarization
D)increased neurotransmitter release
E)decreased neurotransmitter release
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46
An action potential is propagated down an unmyelinated neuronal plasma membrane because it stimulates voltage-gated ____ channels adjacent to it. (Choose the most accurate answer.)​

A)Na+
B)Ca2+
C)K+
D)Na+ and Ca2+
E)K+ and Ca2+
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47
The binding of a neurotransmitter to ligand-gated K+ channels will cause ____ in the postsynaptic membrane. ​

A)depolarization only
B)hyperpolarization
C)repolarization only
D)apolarization
E)depolarization and repolarization
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48
In vertebrates, the neurotransmitter acetylcholine ____. ​

A)can act as a direct neurotransmitter between neurons and muscle cells
B)is involved in memory and learning
C)can be released into the circulation and act as a hormone
D)can act as a pain reducer and initiate euphoria
E)is involved in pain perception
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49
The duration of an action potential is approximately five ____.

A)microseconds
B)milliseconds
C)centiseconds
D)seconds
E)nanoseconds
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50
Action potentials are propagated in a one-way direction down a neuronal plasma membrane because ____. ​

A)the action potential is of insufficient intensity to stimulate the voltage-gated ion channels behind it
B)the adjacent channels upstream from the action potential are ligand-gated
C)the adjacent channels upstream from the action potential are in a refractory period
D)voltage-gated ion channels are suppressed
E)the adjacent channels upstream from the action potential are at their threshold potential
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51
The magnitude of an action potential ____ as it is propagated down an excitable membrane due to the ____ principle. ​

A)increases; all-or-nothing principle
B)remains constant; all-or-nothing principle
C)increases; threshold principle
D)remains constant; threshold principle
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52
Which neurotransmitter is most likely to be inhibitory? ​

A)glutamate
B)dopamine
C)Substance P
D)GABA
E)acetylcholine
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53
The binding of a neurotransmitter to ligand-gated Na+ channels will cause ____ in the postsynaptic membrane. ​

A)depolarization only
B)hyperpolarization
C)repolarization only
D)apolarization
E)depolarization and repolarization
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54
Neuropeptide neurotransmitters ____. ​

A)can act as direct neurotransmitters between neurons and muscle cells
B)can act as postsynaptic membrane inhibitors
C)directly open K+ channels to inhibit neurons
D)can act as pain reducers and initiate euphoria
E)directly inhibit euphoria
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55
When an action potential reaches the axon terminal, the ____ channels are activated to trigger synaptic vesicle release. ​

A)voltage-gated Cl- channels
B)voltage-gated Ca2+ channels
C)voltage-gated Na+ channels
D)ligand-gated Cl- channels
E)ligand-gated Ca2+ channels
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56
Action potential propagation is the fastest in ____. ​

A)a myelinated axon with a small diameter
B)an unmyelinated axon with a small diameter
C)a myelinated axon with a large diameter
D)an unmyelinated axon with a large diameter
E)all myelinated axons regardless of diameter
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57
Place the events in chemical synapse transmission in the correct order.
​1.Ca2+ enters axon terminal.
2. Ligand-gated ion channels open in postsynaptic membrane.
3.Neurotransmitter binds to postsynaptic receptor.
4.Action potential reaches axon terminal of presynaptic neuron.
5.Neurotransmitter released by exocytosis.

A)4, 1, 5, 3, 2
B)4, 3, 1, 5, 2
C)4, 5, 1, 3, 2
D)4, 1, 3, 5, 2
E)4, 5, 2, 3, 1
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58
The binding of a neurotransmitter to ligand-gated Cl - channels will cause ____ in the postsynaptic membrane. ​

A)depolarization only
B)hyperpolarization
C)repolarization only
D)apolarization
E)depolarization and repolarization
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59
Jean-Luc Eiselé and his coworkers used ______ receptors in their research on neurotransmitter receptor function. ​

A)African clawed frog
B)toad
C)artificial
D)dog
E)human
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60
The neurotransmitter receptor research of Jean-Luc Eiselé and his coworkers showed that ____. ​

A)neurotransmitters are dependent on the activity of Na+
B)neurotransmitters are dependent on the activity of K+
C)neurotransmitters are dependent on the activity of Cl
D)neurotransmitters are dependent on the activity of Ca+
E)the parts of a receptor binding a neurotransmitter and conducting ions function independently
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61
Match between columns
occurs when a membrane potential becomes more negative than its resting membrane potential
depolarization
occurs when a membrane potential becomes more negative than its resting membrane potential
repolarization
occurs when a membrane potential becomes more negative than its resting membrane potential
hyperpolarization
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62
Match between columns
describes the change in resting membrane potential that causes it to approach threshold potential
depolarization
describes the change in resting membrane potential that causes it to approach threshold potential
repolarization
describes the change in resting membrane potential that causes it to approach threshold potential
hyperpolarization
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63
Match between columns
begins when Na + channel inactivation gates close and K + activation gates open
depolarization
begins when Na + channel inactivation gates close and K + activation gates open
repolarization
begins when Na + channel inactivation gates close and K + activation gates open
hyperpolarization
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64
At which neuronal structure does summation occur? ​

A)dendrites
B)cell body
C)axon hillock
D)Schwann cells
E)axon terminals
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65
To which class of neurotransmitters does dopamine belong? ​

A)acetylcholine
B)monoamines
C)amino acids
D)neuropeptides
E)gaseous neurotransmitters
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66
Match between columns
the phase of an action potential when the membrane potential becomes more positive
depolarization
the phase of an action potential when the membrane potential becomes more positive
repolarization
the phase of an action potential when the membrane potential becomes more positive
hyperpolarization
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67
Match between columns
occurs in a postsynaptic membrane when ligand-gated Na+ channels open
depolarization
occurs in a postsynaptic membrane when ligand-gated Na+ channels open
repolarization
occurs in a postsynaptic membrane when ligand-gated Na+ channels open
hyperpolarization
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68
A graded, subthreshold change in the postsynaptic membrane potential that moves it toward threshold is called a(n)____. ​

A)IPSP
B)hyperpolarization
C)EPSP
D)depolarization
E)repolarization
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69
Approximately how many neurons comprise the human brain?

A)1,000
B)50,000
C)100,000
D)75,000,000
E)86,000,000,000
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70
Despite recent advances, ___ is/are needed to revolutionize the field of neuroscience and allow for better understanding of neural networking

A)genomics
B)proteomics
C)computational simulations
D)genetic engineering
E)enhanced microscopic techniques
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71
Which neuronal structure has the greatest density of voltage-gated Na+ channels, resulting in the lowest threshold potential along a neuron? ​

A)dendrites
B)cell body
C)axon hillock
D)axon
E)axon terminals
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72
Assume a neuron receives EPSPs and IPSPs from several adjacent neurons. How might that neuron's threshold potential be reached, causing it to produce its own action potential?

A)if IPSPs outnumber EPSPs
B)if IPSPs equal EPSPs
C)if EPSPs outnumber IPSPs
D)if the adjacent neurons contain many axon terminals
E)if the receiving neuron contains many dendrites
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73
Match between columns
causes a neuron membrane potential to become more negative, allowing it to approach its resting potential
depolarization
causes a neuron membrane potential to become more negative, allowing it to approach its resting potential
repolarization
causes a neuron membrane potential to become more negative, allowing it to approach its resting potential
hyperpolarization
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74
Match between columns
occurs due to the diffusion of Na +
depolarization
occurs due to the diffusion of Na +
repolarization
occurs due to the diffusion of Na +
hyperpolarization
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75
Match between columns
occurs in a postsynaptic membrane when ligand-gated Cl - channels open
depolarization
occurs in a postsynaptic membrane when ligand-gated Cl - channels open
repolarization
occurs in a postsynaptic membrane when ligand-gated Cl - channels open
hyperpolarization
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76
Match between columns
an EPSP, for example
depolarization
an EPSP, for example
repolarization
an EPSP, for example
hyperpolarization
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77
To which class of neurotransmitters does glutamate belong?

A)acetylcholine
B)monoamines
C)amino acids
D)neuropeptides
E)gaseous neurotransmitters
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78
Match between columns
an IPSP, for example
depolarization
an IPSP, for example
repolarization
an IPSP, for example
hyperpolarization
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79
To which class of neurotransmitters does substance P belong?

A)acetylcholine
B)monoamines
C)amino acids
D)neuropeptides
E)gaseous neurotransmitters
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80
After burning your hand on a hot burner, which neurotransmitter will most likely be released from the pain receptors? ​

A)glutamate
B)dopamine
C)substance P
D)GABA
E)acetylcholine
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