Deck 22: Sterile Compounding

Question 1

Which of the following is false about disadvantages of parenteral administration?

A) risk of tissue toxicity from local irritation
B) asepsis required at administration
C) more readily controls the therapeutic response of a drug
D) difficulty in correcting errors

Answer 1

more readily controls the therapeutic response of a drug

Question 2

Which statement is false about parenteral products?

A) They must be free from visible particles.
B) They must be chemically and physically unstable.
C) They must be free from contamination by endotoxins.
D) They should be isotonic.

Answer 2

They must be chemically and physically unstable.

Question 3

Which of the following is true about a HEPA filter?

A) It removes 85% of possible contaminants.
B) It removes 90% of possible contaminants
C) It removes 95% of possible contaminants.
D) It removes 99% of possible contaminants.

Answer 3

It removes 99% of possible contaminants.

Question 4

The time from when a sterile drug product is compounded until it is administered to a patient is referred to as its

A) time to time
B) origination date
C) expiration date
D) beyond-use date

Question 5

All aseptic procedures should be performed how far inside a laminar airflow workbench?

A) 3 inches from the front edge
B) 6 inches from the front edge
C) 9 inches from the front edge
D) 12 inches from the front edge

Question 6

The work surface of the laminar airflow hood should be cleaned with

A) 10% bleach
B) 30% isopropyl alcohol
C) 50% isopropyl alcohol
D) 70% isopropyl alcohol

Question 7

HEPA filters need to be certified every

A) 3 months
B) 6 months
C) 12 months
D) 3 to 5 years

Question 8

How many types of asepsis are used in the hospital?

A) 2
B) 3
C) 4
D) 5

Question 9

According to the USP, low-risk compounding products can be kept in a refrigerator for

A) 1 day
B) 3 days
C) 7 days
D) 14 days

Question 10

The process of killing all microorganisms and their pathogenic products is known as

A) sanitization
B) sterilization
C) disinfection
D) cleaning and disinfection

Question 11

The HEPA filter should be serviced and certified

A) every month
B) every 3 months
C) every 6 months
D) every year

Question 12

A vertical laminar airflow hood is used for

A) chemotherapeutic agents
B) sterile product mixtures
C) unit-dose parenteral medications
D) nonsterile products

Question 13

The most common sterile irrigations include

A) gentamicin irrigation solution
B) neomycin irrigation solution
C) hydrochloride irrigation solution
D) chloride potassium solution

Question 14

The work area is bathed by positive, pressurized flowing air called

A) HEPA filter
B) hood
C) laminar
D) workbench

Question 15

Small spills of body fluids on the counter surfaces of a pharmacy must be cleaned with

A) household bleach
B) 20% isopropyl alcohol
C) 70% isopropyl alcohol
D) 100% isopropyl alcohol

Question 16

How long must the blower run in a laminar airflow hood prior to use?

A) 10 minutes
B) 20 minutes
C) 30 minutes
D) 60 minutes

Question 17

A device that uses a combination of heat, steam, and pressure to sterilize equipment is known as a(n)

A) laminar airflow hood
B) dry oven
C) microwave
D) autoclave

Question 18

The most effective method for destruction of all types of microorganisms is

A) laminar airflow hood
B) autoclave
C) oven
D) alcohol pad

Question 19

The process for compounding ophthalmics properly takes

A) from 1 to 2 days
B) from 3 to 5 days
C) from 1 to 2 weeks
D) from 2 to 3 weeks

Question 20

Complete destruction of organisms after they leave the body is referred to as

A) surgical asepsis
B) sterilization
C) medical asepsis
D) sanitization

Question 21

Items that cannot be cleaned at once are usually rinsed with ____________________ and placed in a soaking solution to prevent the residue from hardening.

Question 22

Popular large volume parenterals include 5% dextrose in water, 0.9% sodium chloride, and ____________________.

Question 23

The single most important means of preventing the spread of infection is frequent and effective ____________________.

Question 24

Chapter of the U.S. ____________________ has set the standards for compounding, preparing, and labeling of sterile drug preparations.

Question 25

Many antibiotics are prepared in laminar airflow hoods as IV ____________________.

Question 26

HEPA filters must be replaced every ____________________ to ____________________ years on average.

Question 27

The medium risk levels for contamination of sterile products under the USP at room temperature are over the time period of ____________________ hours.

Question 28

The labels of irrigations state that they are used for ____________________.

Question 29

Laminar airflow hoods are used to prepare sterile compounds by circulating air through ____________________ filters to remove 99% of possible contaminants.

Question 30

There are two types of laminar airflow hoods: vertical and ____________________.

Question 31

The abbreviation for 5% dextrose in normal saline with 0.9% sodium chloride is ____________________.

Question 32

The pharmacy technician should avoid spraying any substances onto the ____________________ when cleaning the laminar airflow hood.

Question 33

Rigid pieces of plastic that are inserted into IV bags are referred to as ____________________.

Question 34

Total parenteral nutrition provides ____________________, proteins, electrolytes, sugars, salts, ____________________, and essential elements designed to meet the entire nutritional needs of the patient.

Question 35

TPN solutions are compounded in ____________________ or in biological safety cabinets.

Question 36

The air moves from a HEPA filter at a rate of 90 to 120 linear ____________________ per minute.

Question 37

Parenteral medications account for more than ____________________ of all medications administered in institutional practice.

Question 38

Small pumps worn by patients are called ____________________ pumps.

Question 39

Ethylene oxide is used to sterilize ____________________ equipment.

Question 40

Ophthalmic medications are compounded in laminar airflow hoods in aseptic conditions, then ____________________ for sterilization.

Question 41

What are six factors that control the choice of a parenteral product's formulation and dosage?

Question 43

Describe how the traditional method of IV piggybacks works.

Question 44

Describe various types of laminar airflow hoods.

Question 45

What topics should be covered by the policies and procedures manual concerning sterile product preparation?

Question 46

Describe how total parenteral nutrition is designed to meet the entire nutritional needs of a patient?