Deck 11: Miscellaneous Agents

Question 1

All of the following statements about Avodart are true, EXCEPT:

A) Female patients of childbearing age should not touch or handle capsules.
B) Avodart predictably increases PSA levels.
C) Adverse drug interactions may include impotence, reduced libido, and ejaculation disturbance.
D) Results of therapy may take several months.

Answer 1

B

Question 2

All of the following are important counseling points about Accutane, EXCEPT:

A) Avoid becoming pregnant while taking Accutane.
B) Avoid prolonged exposure to the sun.
C) Avoid use of alcohol while taking Accutane.
D) Exacerbations of acne can occur during the first week of treatment.

Answer 2

C

Question 3

Which of the following nicotine replacement agents is known to cause dyspepsia?

A) Nicotine Transdermal Patch 7 mg/ day
B) Nicotine Transdermal Patch 21 mg/ day
C) Nicotrol nasal spray
D) Nicotine gum

Answer 3

D

Question 4

What is the maximum infusion rate of potassium chloride that can be given via central line, with continuous EKG monitoring?

A) 20 mEq/hr
B) 30 mEq/hr
C) 40 mEq/hr
D) 80 mEq/hr

Question 5

All of the following statements about isotretinoin are true, EXCEPT:

A) There is a maximum of three refills permitted.
B) Pharmacists should dispense no more than a 30-day supply.
C) Isotretinoin prescriptions must be filled within 7 days of the date of the "qualification."
D) Pharmacists dispensing isotretinoin must be active in the iPLEDGE risk management program.

Question 6

Which of the following is/are adverse effects associated with meclizine?

A) Drowsiness
B) Diarrhea
C) Xerostomia
D) A and C

Question 7

All of the following are indications for hydroxychloroquine, EXCEPT:

A) Systemic lupus erythematosus
B) Rheumatoid arthritis
C) Ventricular arrhythmias
D) Malaria

Question 8

Which of the following statements about colchicine is true?

A) The recommended dose for treatment of acute gout flares is 0.6 mg twice daily.
B) A low purine diet is recommended to decrease the frequency of gout attacks while on this medication.
C) Insomnia and constipation are common side effects.
D) Colchicine should not be used concomitantly with uric acid-lowering therapy.

Question 9

Which of the following is/are indications for Cogentin?

A) Parkinsonism
B) Alzheimer's disease
C) Drug-induced extrapyramidal symptoms
D) A and C are correct

Question 10

All of the following are counseling points regarding varenicline, EXCEPT:

A) Avoid eating or drinking anything 15 minutes prior to taking varenicline.
B) Report changes in mood (e.g., depression, suicide ideation, emotional behavioral changes) to your healthcare provider.
C) Take evening maintenance dose with dinner instead of at bedtime if insomnia occurs.
D) Start varenicline 1 week prior to quit date.

Question 11

Which of the following antigout medications does NOT require dosage adjustment in a patient with renal impairment?

A) Allopurinol
B) Colchicine
C) Febuxostat
D) None of the above

Question 12

Which of the following doses of Plaquenil is correct for the treatment of an acute malaria attack?

A) 400-600 mg orally initially, followed by 800 mg at 6, 24, and 48 hours
B) 200-400 mg once daily for 4 weeks
C) 400 mg orally once or twice daily for 7-10 days
D) 800 mg orally initially, followed by 400 mg at 6, 24, and 48 hours

Question 13

Which of the following is NOT an appropriate counseling point regarding nicotine replacement therapy?

A) Patients should be advised to stop smoking upon initiation of nicotine replacement therapy.
B) Adverse reactions of the nicotine patch include: insomnia, vivid dreams, and local skin reactions.
C) Patients should be instructed to tilt their head back slightly and to not sniff or inhale while administering Nicotrol nasal spray.
D) Patients should be instructed to chew the nicotine lozenge once a tingling sensation or "peppery taste" occurs.

Question 14

Which of the following is a contraindication for administration of flumazenil?

A) Tricyclic antidepressant overdose
B) Renal impairment
C) Opioid overdose
D) Acetaminophen overdose

Question 15

All of the following are important adverse reactions to consider with the oral formulation of potassium chloride, EXCEPT:

A) GI ulcer
B) Hyperkalemia
C) Extravasation
D) Diarrhea

Question 16

Which of the following is a common adverse reaction of VESIcare?

A) Constipation
B) Memory impairment
C) Tachycardia
D) Ejaculation disturbances

Question 17

Use of finasteride should be avoided in which of the following patients?

A) 48-year-old male with male-pattern baldness
B) 78-year-old male with large prostate size and lower urinary tract symptoms
C) 15-year-old male with urinary urgency and nocturia
D) 65-year-old male with lower urinary tract symptoms and family history of prostate cancer

Question 18

Which of the following dose adjustments could be needed for Cialis?

A) No dose adjustments necessary
B) Impaired renal function dose adjustment only
C) Impaired hepatic function dose adjustment only
D) Impaired renal and hepatic function dose adjustments

Question 19

All of the following medications increase the drug concentration of colchicine, EXCEPT:

A) Dapsone
B) Digoxin
C) Verapamil
D) Ketoconazole

Question 20

All of the following are counseling points for allopurinol, EXCEPT:

A) CBC, LFTs, uric acid levels, and renal function tests should be ordered periodically to monitor for effectiveness and adverse effects.
B) Avoid large amounts of vitamin C as it may acidify urine, thus increasing the chance of kidney stone formation.
C) Allopurinol may increase sensitivity to sunlight. Therefore, recommend patients to wear dark glasses, protective clothing, use sunblock, and avoid direct exposure to sunlight.
D) Take allopurinol with food to minimize GI upset.

Question 21

Oxybutynin is contraindicated in all of the following conditions, EXCEPT:

A) Patients > 65 years of age
B) Uncontrolled narrow-angle glaucoma
C) Urinary retention
D) Gastric retention

Question 22

Tolterodine is available in which of the following dosage forms?

A) Capsule
B) Transdermal patch
C) Topical gel
D) All of the above

Question 23

All of the following are true regarding Cogentin, EXCEPT:

A) Cogentin may cause constipation and xerostomia.
B) Taking Cogentin and drinking alcohol may result in increased CNS depression.
C) Cogentin is used in the treatment of tardive dyskinesia.
D) Cogentin may be given via the oral, IM, or IV route.

Question 24

Which of the following is an appropriate dosing regimen for Levitra?

A) 10 mg orally 60 minutes prior to sexual activity
B) 100 mg orally 60 minutes prior to sexual activity
C) 10 mg orally daily
D) All of the above

Question 25

Nicotine replacement therapy comes in all dosage forms, EXCEPT:

A) Gum
B) Tablet
C) Patch
D) Nasal spray

Question 26

Which of the following is a contraindication for the use of phenazopyridine?

A) G6PD deficiency
B) CrCl < 50 ml/min
C) Pregnancy
D) Concomitant treatment with sulfonamide antibiotics

Question 27

Suboxone is available in which of the following dosage forms?

A) Patch
B) Sublingual film strip
C) Nasal spray
D) Gum

Question 28

The brand name of naloxone is:

A) Niacin
B) Narcan
C) Romazicon
D) Acetadote

Question 29

Flumazenil acts as an antagonist at which of the following receptors?

A) Mu
B) Kappa
C) Sigma
D) GABA

Question 30

When using acetylcysteine orally for acetaminophen overdose, there are _______ total doses.

A) 3
B) 10
C) 15
D) 18

Question 31

Which of the following best describes the mechanism of action of Myrbetriq?

A) Muscarinic acetylcholine receptor inhibition increases bladder capacity
B) Beta-3 adrenergic receptor inhibition increases bladder capacity
C) Alpha-1 adrenergic receptor inhibition relaxes the prostate and bladder neck
D) Exerts local anesthetic action on the urinary tract mucosa

Question 32

Following initiation of AndroGel, when should the first measurement of serum testosterone levels occur?

A) 7 days
B) 14 days
C) 4 weeks
D) 3 months

Question 33

Magnesium oxide may decrease the pharmacologic effect of which of the following drugs?

A) Levothyroxine
B) Warfarin
C) Penicillin
D) Combined oral contraceptives

Question 34

In which of the following dosage forms is promethazine available?

A) Capsule
B) Transdermal patch
C) Rectal suppository
D) Buccal lozenge

Question 35

Which of the following is an appropriate counseling point for scopolamine?

A) The patch may be cut if a smaller dose is needed.
B) The patch should be placed on the upper arm or shoulder.
C) The patch should be replaced every 24 hours.
D) Remove the patch prior to MRI to avoid skin burns.