Deck 12: Leukocyte Development, Kinetics, and Functions

Question 1

What is the last granulocyte in the maturation sequence able to undergo mitosis?

A)myeloblast
B)promyelocyte
C)myelocyte
D)band

Answer 1

myelocyte

Question 2

Mature mast cells are

A)leukocytes.
B)tissue effector cells.
C)progenitor cells.
D)cytokines.

Answer 2

tissue effector cells.

Question 3

Which of the following has the most controversial morphologic identification system?

A)progenitor cells
B)stem cells
C)promyelocytes
D)bands

Answer 3

bands

Question 4

Select the correct maturation sequence for granulocytes starting with youngest.

A)promyelocyte, myeloblast, metamyelocyte, myelocyte, segmented
B)myeloblast, promyelocyte, myelocyte, metamyelocyte, band, segmented
C)segmented, band, metamyelocyte, myelocyte, promyelocyte, myeloblast
D)CFU-GEMM, promyelocyte, metamyelocyte, myelocyte, segmented

Question 5

What is the earliest stage of maturation where a neutrophil can be distinguished from an eosinophil?

A)myeloblast
B)CFU-GEMM
C)metamyelocyte
D)myelocyte

Question 6

Which of the following cells is described as a large cell with abundant blue-grey cytoplasm containing minute granules,lacy or stringy chromatin,and an indented or folded nucleus?

A)monocyte
B)macrophage
C)lymphocyte
D)basophil

Question 7

Which cells are responsible for antibody production?

A)macrophages
B)monocytes
C)neutrophils
D)plasma cells

Question 8

A segmented neutrophil performs all of the following except

A)chemotaxis.
B)phagocytosis.
C)mitosis.
D)pinocytosis.

Question 9

A cell having a round nucleus with delicate chromatin,two to four prominent nucleoli,and a high N:C ratio of 8:1 with scant basophilic cytoplasm is an accurate description of a

A)myeloblast.
B)myelocyte.
C)metamyelocyte.
D)band.

Question 10

What pools of neutrophils are included in the marginal neutrophil pool (MNP)?

A)all neutrophils inside the blood vessels
B)only freely circulating neutrophils
C)only cells loosely localized to the vessel walls
D)all leukocytes in the body

Question 11

Why is the bone marrow (storage)pool of granulocytes so large compared with the total number found in peripheral blood?

A)They prefer bone marrow to peripheral blood.
B)They can be quickly released when needed to fight bacterial infection.
C)It enhances their ability to function.
D)It prolongs their lifespan in circulation.

Question 12

Response to parasitic infections is associated with an increase of which type of granulocyte?

A)promyelocytes
B)band neutrophils
C)segmented neutrophils
D)eosinophils

Question 13

Which cells are normally produced in multiple sites including the bone marrow,thymus,and spleen?

A)monocytes
B)lymphocytes
C)eosinophils
D)basophils

Question 14

What directs the mitosis and maturation action of progenitor neutrophil cells in the bone marrow?

A)erythropoietin.
B)the number of stem cells.
C)the number of mature cells in the peripheral circulation.
D)colony-stimulating factor cytokines.

Question 15

What is the primary function of the neutrophils?

A)antibody production
B)phagocytosis
C)kill parasites
D)respond to allergens

Question 16

Which of the following is a feature of a normal segmented neutrophil?

A)basophilic cytoplasm
B)round nucleus with fine chromatin
C)small pink-lilac granules
D)prominent primary granules

Question 17

What is the earliest morphologically identifiable cell in the granulocyte maturation sequence?

A)hematopoietic stem cell
B)colony-forming unit-granulocyte, erythrocyte, monocyte, and megakaryocyte (CFU-GEMM)
C)myeloblast
D)myelocyte

Question 18

When monocytes reside in the tissues they are referred to as

A)mast cells.
B)T cells.
C)plasma cells.
D)macrophages.

Question 19

B cells and T cells are subgroups of what cell type?

A)monocytes
B)lymphocytes
C)macrophages
D)plasma cells

Question 20

Which of the following neutrophils is capable of chemotaxis?

A)stem cell
B)progenitor cell
C)myelocyte
D)segmented neutrophil