Deck 15: The Skin and Eye: Most Likely Exposure Routes and Toxicities Due to Contact Exposure and Dose Toxicities

Question 1

Why does a strong solvent appear to give a burn?

Answer 1

These solvents remove essential fats and oils which causes a loss of hydration. This is accompanied by high penetration of these solvents and deep damage that may appear as a burn.

Question 2

What skin reactions involve T cells or proinflammatory release of cytokines from keratinocytes?

Answer 2

Contact dermatitis involves irritant

Question 3

What type of acne is indicative of more serious internal toxicity?

Answer 3

Exposure to chlorinated dibenzodioxins cause chloracne that indicate internal organ toxicity that also can result in future cancer or death.

Question 4

Why do dogs develop a corneal opacity to 1,2-dichloroethane?