Deck 27: Inorganic Chemistry in Medicine

Question 1

Platinum has two common oxidation states, +2 and +4. Which one is found in effective cancer therapy drugs?

A) +2 only.
B) +4 only.
C) both +2 and +4.

Answer 1

C

Question 2

Gold has two common oxidation states, +1 and +3. Which one is found in drugs used for treatment of rheumatoid arthritis?

A) +1
B) +3
C) both +1 and +3

Answer 2

A

Question 3

Which Bi(III) complexes are commonly used in the treatment of gastric ulcers?

A) Mononuclear Bi(III) complexes with sulfur donor ligands.
B) Polynuclear Bi(III) complexes with sulfur donor ligands.
C) Polynuclear Bi(III) complexes with oxygen donor ligands.

Answer 3

C

Question 4

Which lithium compound is used in "lithium therapy" for bipolar disorders?

A) LiCl
B) LiNO₃
C) LiOH

Question 5

What are the CO-releasing drugs used for?

A) Treatment of heavy metal poisoning.
B) Treatment of post-operative stress.
C) As antiviral agents.

Question 6

Chelation therapy uses ligands inspired by ___________ in order to treat Fe overload.

A) siderophore structures
B) crown ethers
C) porphyrin rings.

Question 7

Which metals are used in imaging agents?

A) Ga and Ta
B) Gd and Tc
C) Ge and Tl

Question 8

Nanoparticles show promise in

A) targeted drug delivery.
B) drug synthesis.
C) treatment of viral diseases.

Question 9

Although As₄O₆ is very poisonous compound, it is found in treatment of

A) bacterial infections.
B) malaria
C) one form of leukaemia.

Question 10

What is one of the major challenges in inorganic medicinal chemistry?

A) Understanding the mechanism of action of inorganic compounds.
B) The diverse side-effects of the metallodrugs.
C) The price of metals used in medicine.