Deck 5: Effects of Exercise on Acquired Immune Function

Question 1

According to the study of Steensberg et al. (2001b), how did acute prolonged strenuous exercise affect the proportion of circulating helper T cells?

A) An increase in the proportion of type-1 T helper cells
B) An increase in the proportion of type-2 T helper cells
C) A decrease in the proportion of type-1 T helper cells
D) A decrease in the proportion of type-1 T helper cells
E) Had no effect on the proportion of type-1 and type-2 T cells

Answer 1

C,D

Question 2

Which of the following is not a mitogen stimulant?

A) Tetanus toxoid
B) Phytohaemaglutinin
C) Concanavalin-A
D) Pokeweed
E) All of the above

Answer 2

A

Question 3

In the study by Green et al. (2002), PHA-stimulated lymphocyte proliferation in a fixed number of lymphocytes fell after a one-hour intensive treadmill run but what happened to the proliferative response when natural killer cells were removed from the proliferation cultures?

A) Proliferation was the same as in the cultures where NK cells were present
B) Proliferation was higher than in the cultures where NK cells were present
C) Proliferation was lower than in the cultures where NK cells were present
D) Proliferation was no longer detectable
E) None of the above

Answer 3

C

Question 4

In the study by Bishop et al. (2009), compared with migration towards uninfected respiratory cells, T-cell migration towards the supernatants of rhinovirus-infected respiratory cells after exercise was...

A) Higher than immediately after exercise before falling during recovery
B) Lower immediately after exercise and during recovery
C) Lower immediately after exercise yet similar during recovery
D) Similar immediately after exercise but lower during recovery
E) None of the above

Question 5

Which of the following are not methods used to assess in vivo immune function?

A) Circulating antibody response to recall antigen vaccination
B) Circulating antibody response to novel antigen vaccination
C) Delayed-type hypersensitivity response
D) Antigen-stimulated T cell proliferative responses
E) All of the above

Question 6

What is the predominant immunoglobulin in the blood?

A) Iγδ
B) IgA
C) IgM
D) IgE
E) IgG

Question 7

Which of the following statements is TRUE?

A) Circulating antibody concentrations are largely unchanged in response to brief and prolonged intensive exercise
B) Circulating antibody concentrations tend to fall after brief and prolonged intensive exercise
C) Mitogen-stimulated IgM concentration appears to decrease in response to exercise independently of changes in T or B cell number
D) Antibody responses to vaccination are generally increased after prolonged exercise
E) IgG antibodies are converted to IgM antibodies following prolonged exercise

Question 8

Which of the following statements is TRUE?

A) Intensified training in associated with increases in B cell immunoglobulin production
B) Athletes always have lower lymphocyte proliferative responses compared with non-athletes
C) Lymphocyte proliferative responses are elevated after period of training in previously sedentary individuals
D) Intensified training in associated with decreases in circulating numbers of type-1 T cells
E) Intensified training in associated with increases in circulating numbers of type-1 T cells and decreases in type-2 T cells

Question 9

In vivo assessments of both cell-mediated immune responses and antibody production suggest that the initial primary response is less affected by exercise than subsequent memory responses.

Question 10

Changes in T cell functions with acute exercise are related to the intensity but not the duration of the exercise bout.