Deck 15: Blood Component Preparation and Therapy

Question 1

Why are plastic overwraps recommended when thawing FFP and CRYO?

A) To prevent contamination of the water bath
B) To prevent rapid thawing, which affects labile factors
C) To prevent entry ports from becoming contaminated with water
D) To prevent the label from peeling off when thawing

Answer 1

C
A plastic overwrap or keeping ports above the water level are acceptable methods for prevention of bacterial contamination from the water bath.

Question 2

Rejuvenation of a unit of RBCs is a method used to:

A) inactivate viruses.
B) restore 2, 3 DPG and ATP levels.
C) increase the expiration date by 21 days.
D) prepare a unit for freezing in high glycerol.

Answer 2

B
The additives in rejuvenation solutions increase the 2,3 DPG and ATP levels of an expired unit and allow for freezing within 3 days.

Question 3

Whole blood collected from a donor should remain at what temperature before the separation and preparation of platelet concentrates?

A) 20° to 24° C
B) 1° to 6° C
C) 1° to 10° C
D) Varies with the facility

Answer 3

A
Platelets must be separated from whole blood units before storage at 1° to 6° C.

Question 4

MATCHING
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.
a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
AS-3 or AS-2

Question 5

Select an important determination of platelet viability following the recommended storage interval.

A) Platelet count
B) pH
C) PTT
D) Oxygen level

Question 6

MATCHING
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.
a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Frozen

Question 7

What is the correct storage temperature and time limit for pooled platelets?

A) 20° to 24° C, 5 days
B) 1° to 6° C, 7 days
C) 1° to 10° C, 24 hours
D) 20° to 24° C, 4 hours

Question 8

MATCHING
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.
a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Irradiated

Question 9

Platelet concentrates that are prepared from whole blood have a minimum quality control limit of __________ platelets in __________ of the units tested.

A) 3 × 10¹¹, 75%
B) 1 × 10¹⁰, 75%
C) 5.5 × 10¹⁰, all
D) 5.5 × 10¹⁰, 75%

Question 10

Following a platelet concentrate transfusion,a patient did not obtain the calculated corrected count increment that was expected.Select the possible reason(s)the increment increase did not occur.

A) Patient had a fever
B) Patient was actively bleeding
C) Patient has leukocyte antibodies
D) All of the above are correct

Question 11

MATCHING
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.
a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
CPDA-1

Question 12

A unit of CPDA-1 RBCs,expiring in 35 days,is split using a sterile collection device to prepare pediatric units.What is the expiration date for each split unit?

A) 4 days from collection
B) 4 days from sterile docking
C) 35 days from collection
D) 28 days from collection

Question 13

What patient population needs leukocyte-reduced red blood cells?

A) Patients with febrile transfusion reactions
B) Patients with iron deficiency anemia
C) Patients with hemophilia A
D) Patients with cancer undergoing chemotherapy treatments

Question 14

MATCHING
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.
a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
CPD

Question 15

Once the cryoprecipitate is removed from fresh frozen plasma,the remaining plasma can be refrozen and stored at -18° C for 1 year from collection.Which of the following clinical conditions can use this product?

A) Thrombotic thrombocytopenic purpura
B) Hemophilia
C) Warfarin overdose
D) Volume replacement following surgery

Question 16

To prevent graft-versus-host disease,blood components prepared for a fetus that needs an intrauterine transfusion should be:

A) saline washed.
B) irradiated.
C) frozen and deglycerolized.
D) human leukocyte antigen-matched.

Question 17

What is the minimum acceptable storage temperature for frozen red blood cells?

A) 4° C
B) -12° C
C) -20° C
D) -65° C

Question 18

Plasma,frozen within 24 hours of collection (PF24),has similar coagulation factors as which of the following plasma products?

A) FFP
B) CRYO
C) Thawed plasma
D) Recovered plasma

Question 19

Addition of which of the following will increase the shelf life of red blood cells?

A) Heparin
B) AS-3
C) Lactated Ringer's
D) Citrate

Question 20

The temperature of a RBC unit shipment from the local blood center was recorded as 8° C upon arrival at the hospital.What is the correct course of action?

A) Place the units in inventory because the temperature is acceptable.
B) Quarantine the units until approved by the supervisor.
C) Send the units back to the blood center.
D) Have the units tested for bacterial contamination before release.

Question 21

Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.
a.20° to 24° C, 4 hours
b.1° to 6° C, 24 hours
c.20° to 24° C, 6 hours
d.< -18° C, 1 year from collection
e.1° to 6° C, up to 5 days
f.< -65° C, 7 years
g.20° to 24° C, 48 hours
Cryoprecipitated AHF (frozen)

Question 22

Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.
a.20° to 24° C, 4 hours
b.1° to 6° C, 24 hours
c.20° to 24° C, 6 hours
d.< -18° C, 1 year from collection
e.1° to 6° C, up to 5 days
f.< -65° C, 7 years
g.20° to 24° C, 48 hours
Plasma,cryoprecipitate reduced,thawed

Question 23

Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.
a.20° to 24° C, 4 hours
b.1° to 6° C, 24 hours
c.20° to 24° C, 6 hours
d.< -18° C, 1 year from collection
e.1° to 6° C, up to 5 days
f.< -65° C, 7 years
g.20° to 24° C, 48 hours
Liquid plasma from whole blood

Question 24

Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.
a.20° to 24° C, 4 hours
b.1° to 6° C, 24 hours
c.20° to 24° C, 6 hours
d.< -18° C, 1 year from collection
e.1° to 6° C, up to 5 days
f.< -65° C, 7 years
g.20° to 24° C, 48 hours
Fresh frozen plasma (thawed)

Question 25

MATCHING
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.
a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Leukoreduced (AS-3)

Question 26

Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.
a.20° to 24° C, 4 hours
b.1° to 6° C, 24 hours
c.20° to 24° C, 6 hours
d.< -18° C, 1 year from collection
e.1° to 6° C, up to 5 days
f.< -65° C, 7 years
g.20° to 24° C, 48 hours
Cryoprecipitated AHF (thawed)

Question 27

Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.
a.20° to 24° C, 4 hours
b.1° to 6° C, 24 hours
c.20° to 24° C, 6 hours
d.< -18° C, 1 year from collection
e.1° to 6° C, up to 5 days
f.< -65° C, 7 years
g.20° to 24° C, 48 hours
Cryoprecipitated AHF (thawed,pooled)

Question 28

MATCHING
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.
a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Deglycerolized

Question 29

MATCHING
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.
a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Apheresis (ACD)