Deck 16: Transfusion Therapy in Selected Patients

Question 1

Who needs the transfusion of CMV-negative blood products?

A) Sickle cell
B) Neonates
C) Cardiac
D) Trauma

Answer 1

B
Because of the low immune system in a neonate,CMV-safe units should be given.

Question 2

A patient,group AB,D-positive,has a bleeding aortic aneurysm.A massive transfusion is undertaken for lifesaving measures.What ABO phenotype is recommended for transfusion to this patient?

A) Group A
B) Group B
C) Group O
D) Group AB

Answer 2

A
Group AB recipients could receive group A or group B but not both; group A is routinely used because of its greater availability in comparison to group B or AB.

Question 3

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Decreases immunization to leukocytes

Answer 3

E

Question 4

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Intravascular volume expansion

Question 5

Why do premature neonates require red blood cell transfusions?

A) Iatrogenic blood loss
B) Hemoglobin F is being changed to hemoglobin A
C) Insufficient erythropoiesis
D) All of the above

Question 6

A patient demonstrated the following symptoms: hypotension,tachycardia,cold or clammy skin,and cyanosis.What is the most likely cause?

A) Anaphylactic shock
B) Graft-versus-host disease
C) Congestive heart failure
D) Hypovolemic shock

Question 7

What term is describes the replacement of one or more blood volumes within 24 hours whether in an infant or in an adult patient?

A) Acute hypovolemic shock
B) Hemorrhage
C) Intravascular shock
D) Massive transfusion

Question 8

Select the clinical situation where iron chelation is recommended to prevent iron overload.

A) Aplastic anemia
B) Autoimmune hemolytic anemia
C) Sickle cell anemia
D) Anemia caused by trauma

Question 9

Risk factors for bleeding during cardiac surgery include all of the following except:

A) length of time on the pump.
B) level of preoperative medications.
C) presence of a red cell antibody.
D) hypothermia.

Question 10

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Reduce the risk of allergic reactions

Question 11

What is the goal of therapeutic apheresis?

A) Reduce a high antibody level
B) Replace cellular elements
C) Clear immune complexes
D) All of the above are correct

Question 12

Massive transfusion replaces 1 blood volume.In a 70-kg adult,how many units of whole blood would be needed?

A) 6
B) 8
C) 10
D) 14

Question 13

Identify the common complications of chemotherapy.

A) Bleeding
B) Infection
C) Anemia
D) All of the above

Question 14

Infants do not require crossmatching if they are less than:

A) 6 months old.
B) 5 months old.
C) 4 months old.
D) 12 months old.

Question 15

Which of the following situations contributes to red blood cell loss in chronic renal disease?

A) Below normal erythropoietin levels
B) Shearing of red cells from kidney dialysis
C) Elevated uremia
D) All of the above

Question 16

Which of the following contributes to the high blood usage in a liver transplant surgery?

A) The liver is a very large organ.
B) It is difficult to find close human leukocyte antigen matches for liver transplants.
C) Platelets are stored in the liver.
D) The liver produces the vitamin K-dependent coagulation factors.

Question 17

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Bleeding due to thrombocytopenia

Question 18

Which of the following is used in the treatment of hemophilia A?

A) Factor VIII concentrate
B) Factor XIII concentrate
C) Platelets
D) Fresh frozen plasma

Question 19

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Treatment of symptomatic anemia

Question 20

What is the most effective component to treat a patient with von Willebrand disease?

A) Fresh frozen plasma
B) Red blood cells
C) Platelets
D) Cryoprecipitated AHF

Question 21

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Deficiency of factors II,V,X,and XI

Question 22

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Avoid graft-versus-host disease

Question 23

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Thrombotic thrombocytopenic purpura

Question 24

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Specific clotting deficiencies of factors VIII,V,and X

Question 25

MATCHING
Match the component with the indications for use.Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Deficiency of factor XIII and von Willebrand factor