Deck 8: Electron Microscopy, Surface Analysis, and Transdermal Drug Delivery

Question 1

Degree of scattering in transmission electron microscope is a function of                      

A)wavelength of electron beam used
B)number of atoms that lie in the electron path
C)number and mass of atoms that lie in the electron path
D)mass of atoms that lie in the electron path

Answer 1

number and mass of atoms that lie in the electron path

Question 2

Negative Staining is used for examining

A)virus particles
B)protein molecules
C)bacterial flagella
D)virus particles, protein molecules and bacterial flagella

Answer 2

virus particles, protein molecules and bacterial flagella

Question 3

Which among the following helps us in getting a three-dimensional picture of the specimen?

A)transmission electron microscope
B)scanning electron microscope
C)compound microscope
D)simple microscope

Answer 3

scanning electron microscope

Question 4

The secondary electrons radiated back in scanning microscope is collected by?

A)specimen
B)anode
C)vacuum chamber
D)cathode

Question 5

On what factors do the intensity of secondary electrons depend upon?

A)shape of the irradiated object
B)chemical composition of the irradiated object
C)number of electrons ejected
D)size and chemical composition of the irradiated object, number of electrons ejected and on the number of electrons reabsorbed by surrounding

Question 6

The resolution attainable with standard TEM is less than the theoretical value.

Question 7

Which of the following component of TEM focuses the beam of electrons on the sample?

A)ocular lens
B)condenser lens
C)stage
D)column

Question 8

Image formation in electron microscope is based on                                                         

A)column length
B)electron number
C)differential scattering
D)specimen size

Question 9

The biological materials have little intrinsic capability to                                           

A)scatter electrons
B)stain
C)remain viable
D)be captured

Question 10

Glutaraldehyde is a                                  

A)metal
B)fixative
C)non-metal
D)atomic species

Question 11

Osmium is a                                         

A)non metal
B)heavy metal
C)alloy
D)light metal

Question 12

In TEM, the tissue is stained by floating on drops of                                               

A)hydrocarbons
B)slow-molecular weight stains
C)heavy metal soutions
D)oil immersion

Question 13

Shadow casting is a technique of visualizing

A)isolated particles
B)mounts
C)shoot tips
D)root tips

Question 14

Surface is usually more than----------atomic layer deep and is a region of ---------- atomic potentials.

A)one, uniform
B)one, non-uniform
C)two, uniform
D)two, non-uniform

Question 15

Surface analysis can provide information that classic methods like microscopic cannot.

Question 16

In surface spectrometer, which of the following beam is analysed?

A)reflected beam
B)absorbed beam
C)refracted beam
D)incident beam

Question 17

Which of the following is a type of electron spectroscopy?

A)mikes
B)auger spectroscopy
C)secondary ion mass spectroscopy
D)ion scattering spectroscopy

Question 18

Surface analysis cannot provide any chemical information directly.

Question 19

Which of the following is also known as X- ray photoelectron spectroscopy?

A)auger electron spectroscopy
B)electron impact spectroscopy
C)electron spectroscopy for chemical analysis
D)secondary ion mass spectroscopy

Question 20

Which of the following methods utilizes the emission of low energy electrons in a process?

A)auger electron spectroscopy
B)electron impact spectroscopy
C)electron spectroscopy for chemical analysis
D)secondary ion mass spectroscopy

Question 21

Which of the following is the abbreviation of ESCA?

A)electron scattering chemical analysis
B)emission spectroscopy combination analysis
C)electron spectroscopy for chemical analysis
D)electron spectrum chemically analysed

Question 22

Which of the following methods use soft X- rays to eject electrons from inner shell orbitals?

A)auger electron spectroscopy
B)electron impact spectroscopy
C)electron spectroscopy for chemical analysis
D)secondary ion mass spectroscopy

Question 23

Which of the following is the abbreviation of SIMS?

A)secondary ion mass spectroscopy
B)spectrum ionization mass spectroscopy
C)scattering ions mass spectroscopy
D)spectral ionization mass spectroscopy

Question 24

Which of the following drugs cannot be given as transdermal administration?

A)drugs with very short half-lives
B)drugs with narrow therapeutic indices
C)easy removal and termination
D)drugs against peptic ulcer

Question 25

Which of the following characteristics is suitable for transdermal drug?

A)large drug dose
B)large molecular size
C)drugs with narrow therapeutic indices
D)drugs which are metabolized in the skin