Deck 44: Antiparasitic Drugs

Question 1

A patient is treated for a Schistosoma mansoni infection.Which mechanism is responsible for the drug's therapeutic effect?

A) increased chloride permeability
B) decreased chloride permeability
C) increased calcium permeability
D) decreased calcium permeability
E) decreased sodium permeability

Answer 1

increased calcium permeability

Question 2

The acute phase of which disease may be shortened by administration of nifurtimox and interferon gamma?

A) visceral leishmaniasis
B) African sleeping sickness
C) onchocerciasis
D) cutaneous larva migrans
E) American trypanosomiasis

Answer 2

American trypanosomiasis

Question 3

Which drug may cause an acute disulfiram-like reaction if taken concurrently with alcohol?

A) metronidazole
B) primaquine
C) ivermectin
D) albendazole
E) pentamidine

Answer 3

metronidazole

Question 4

Which antiprotozoal agent inhibits enzymes involved in glycolipid metabolism in sensitive organisms?

A) nitazoxanide
B) paromomycin
C) miltefosine
D) tinidazole
E) mefloquine