Deck 15: Drugs for Hyperlipidemia

Question 1

Dietary modifications that lower the ratio of LDL-cholesterol to HDL-cholesterol include an increased intake of which nutrient?

A) trans isomers of fatty acids
B) saturated fat
C) polyunsaturated fat
D) omega-3 (n-3) fatty acids
E) partially hydrogenated plant oils

Answer 1

omega-3 (n-3) fatty acids

Question 2

In addition to their beneficial effect on serum LDL-cholesterol levels, atorvastatin and related drugs may reduce coronary heart disease by which mechanism?

A) reducing cholesterol absorption
B) improving vascular endothelial function
C) stimulating lipoprotein lipase
D) increasing lipolysis
E) decreasing appetite

Answer 2

improving vascular endothelial function

Question 3

A man taking simvastatin develops severe muscle pain, muscle inflammation,
And dark urine after beginning concurrent therapy with another drug.Which agent is most likely responsible for this adverse drug interaction?

A) ezetimibe
B) cholestyramine
C) itraconazole
D) rifampin
E) penicillin

Answer 3

itraconazole

Question 4

At what level of serum LDL-cholesterol do persons with symptomatic coronary artery disease benefit from drug therapy to lower these levels?

A) >175 mg/dL
B) >150 mg/dL
C) >100 mg/dL
D) >70 mg/dL
E) They benefit regardless of level.