Deck 16: Anticoagulant, Antiplatelet, and Fibrinolytic Drugs

Question 1

A patient receives a cyclic peptide derived from rattlesnake venom.Which step leading to platelet aggregation is inhibited by this agent?

A) glycoprotein IIb/IIIa expression
B) ADP binding
C) fibrinogen binding
D) cyclic AMP formation
E) 5-hydroxytryptamine synthesis

Answer 1

fibrinogen binding

Question 2

Which coagulation factor is inactivated following administration of lepirudin?

A) tissue thromboplastin
B) fibrinogen
C) prothrombin
D) active factor X
E) thrombin

Answer 2

active factor X

Question 3

Which anticoagulant consists of a synthetic antithrombin III-binding pentasaccharide?

A) fondaparinux
B) bivalirudin
C) warfarin
D) heparin
E) enoxaparin

Answer 3

fondaparinux