Deck 20: Antiepileptic Drugs

Question 1

A woman with epilepsy is instructed to take larger doses of vitamin D than are usually recommended. Which drug is most likely being taken by this patient?

A) valproate
B) phenytoin
C) phenobarbital
D) gabapentin
E) topiramate

Answer 1

phenytoin

Question 2

A child whose seizures have been controlled with valproate experiences breakthrough seizures and lamotrigine is being added to the regimen. Which adverse effect is more common in children receiving both drugs?

A) aplastic anemia
B) hepatitis
C) Stevens-Johnson syndrome
D) megaloblastic anemia
E) gingival hyperplasia

Answer 2

Stevens-Johnson syndrome

Question 3

After sustaining head trauma, a woman experiences recurrent tonic-clonic seizures without regaining consciousness.
Which pair of drugs is most often used to control this type of seizure?

A) valproate and carbamazepine
B) zonisamide and gabapentin
C) topiramate and vigabatrin
D) diazepam and phenytoin
E) pregabalin and tiagabine

Answer 3

diazepam and phenytoin

Question 4

Which pair of drugs produces antiepileptic effects by blocking T-type calcium channels in neuronal membranes?

A) topiramate and vigabatrin
B) gabapentin and pregabalin
C) zonisamide and carbamazepine
D) lamotrigine and topiramate
E) ethosuximide and valproate