Deck 43: Antiviral Drugs

Question 1

A man receives a drug that binds to chemokine co-receptor 5. Which step in viral replication is prevented by this drug?

A) binding of viral glycoprotein120 to host CD4 cells
B) transfer of viral nucleic acid into host cells
C) formation of a DNA copy of viral RNA
D) integration of viral DNA into host cell genome
E) expression of viral proteins

Answer 1

transfer of viral nucleic acid into host cells

Question 2

A man receives a drug that binds cations essential for the catalytic activity of an enzyme required for HIV replication. Which step is blocked by this drug?

A) viral maturation and release
B) interaction of the viral enzyme and host cell DNA
C) insertion of glycoprotein 41 into host cell membranes
D) formation of a DNA copy of viral RNA
E) binding of glycoprotein 120 to CD4 antigen

Answer 2

interaction of the viral enzyme and host cell DNA

Question 3

A woman is placed on a drug that binds HIV reverse transcriptase and is being monitored for drug-induced neuropsychiatric reactions. This drug should not be taken by persons with which condition?

A) cardiac arrhythmia
B) hypercholesterolemia
C) pancreatitis
D) pregnancy
E) diabetic neuropathy

Answer 3

pregnancy

Question 4

Which antiviral agent is active against viruses that cause several hemorrhagic fevers, such as Rift Valley fever virus?

A) ganciclovir
B) lamivudine
C) interferon alfa
D) foscarnet
E) ribavirin