Question 1

Malaria is a serious disease that is caused by a:&#10;A) bacterium&#10;B) catabolism&#10;C) fungi&#10;D) protozoan

Accepted Answer

D) Malaria is caused by a protozoan transmitted to humans by mosquitoes. Protozoans are microorganisms that include all the acellular or loosely held together, nontissued unicellular forms.

Question 2

The ideal antimalarial should eradiate the microzoan from the blood and the tissue to ensure:&#10;A) a cycle&#10;B) resistance&#10;C) prevention&#10;D) a radical cure

Accepted Answer

D) The ideal antimalarial should eradicate the microzoan not only from the blood but also from the tissue to affect a radical cure. For treatment of malaria, several antimalarial agents differ in their points of interruption of the cycle of the parasite, and in the type of malaria affected.

Question 3

Malaria is caused by several species of the protozoan:&#10;A) P. ovale&#10;B) Plasmodium&#10;C) Anopheles&#10;D) microzoan

Accepted Answer

B) Malaria is caused by several species of the protozoan Plasmodium, of which Plasmodium vivax and Plasmodium falciparum are the most common. The most serious infections involve P. falciparum, which causes a higher incidence of complications and deaths.

Question 4

The drug of choice for the treatment of most types of malaria is:&#10;A) nucleic acid&#10;B) quinine&#10;C) chloroquine&#10;D) quinidine

Accepted Answer

C) The drug of choice for the (oral) treatment of most types of malaria is chloroquine. It is used for all types of malaria except that caused by resistant P. falciparum. Chloroquine is a protozoacidal drug, and destroys Plasmodia organisms by interfering with their metabolism, or inhibiting normal replication of the protozoan.

Question 5

An antimalarial agent that is very important for the radical cure of relapsing P. vivax or P. ovale malaria is:&#10;A) quinine&#10;B) primaquine&#10;C) quinidine&#10;D) hydroxychloroquine

Accepted Answer

B) An antimalarial agent that is very important for the radical cure of relapsing P. vivax or P. ovale malaria is primaquine. It is not used for suppressive therapy, or for the control of the acute clinical attacks of the disease.

Question 6

The treatment of choice for severe P. falciparum infection is:&#10;A) quinidine&#10;B) quinine&#10;C) primaquine&#10;D) hydroxychloroquine

Accepted Answer

B) The treatment of choice for severe P. falciparum infection is quinine. A chemically related drug-quinidine gluconate-is an antidysrhythmic drug that is used off-label to treat severe malaria via IV administration.

Question 7

A drug used adjunctively with primaquine to eradicate P. vivax and P. malariae is:&#10;A) quinidine&#10;B) hydroxychloroquine&#10;C) quinine&#10;D) chloroquine

Accepted Answer

B) Hydroxychloroquine is used adjunctively with primaquine to eradicate P. vivax and P. malariae. It is also commonly prescribed for the treatment of rheumatoid arthritis and lupus erythematosus.

Question 8

Two protozoal organisms-Entamoeba histolytica and Giardia lamblia-frequently cause:&#10;A) thrush&#10;B) dermatophyte infections&#10;C) malaria&#10;D) dysentery

Accepted Answer

D) Dysentery is frequently caused by the organisms Entamoeba histolytica and Giardia lamblia. It is an infection that is also known as amebiasis. Dysentery is most common in areas of the world with poor sanitation and economic conditions, including Central America, South America, Africa, and India.

Question 9

The most commonly reported intestinal protozoal infection in the United States is:&#10;A) giardiasis&#10;B) dysentery&#10;C) amebiasis&#10;D) colitis

Accepted Answer

A) Giardiasis is the most commonly reported intestinal protozoal infection in the United States. It is an infection in which trophozoites attach to the mucosa of the duodenum and jejunum, then multiply using binary fission. Most cases of giardiasis are transmitted through contaminated water or food, sexual contact, and other direct contact.

Question 10

Which of the following is indicated for trichomoniasis, acute intestinal amebiasis, and amebic liver abscess?&#10;A) hydroxychloroquine&#10;B) quinidine&#10;C) metronidazole&#10;D) iodoquinol

Accepted Answer

C) Metronidazole is indicated for trichomoniasis, acute intestinal amebiasis, and amebic liver abscess. It is direct-acting, and usually indicated for preoperative prophylaxis in colorectal surgery, elective hysterectomy or vaginal repair, and emergency appendectomy.

Question 11

Iodoquinol is an anti-infective, antiprotozoal, and:&#10;A) antiamebicide agent&#10;B) antiemetic agent&#10;C) analgesic agent&#10;D) antiseptic agent

Accepted Answer

The answer of Iodoquinol is an anti-infective, antiprotozoal, and:&#10;A) antiamebicide...

Question 12

Gametes are:&#10;A) germ cells&#10;B) sperm cells&#10;C) egg cells&#10;D) liver cells

Accepted Answer

The answer of Gametes are:&#10;A) germ cells&#10;B) sperm cells&#10;C) egg...

Question 13

Trichomonas vaginalis causes trichomoniasis, which is common in the United States and is transmitted:&#10;A) by insects&#10;B) by contact with the infected skin of another person&#10;C) sexually&#10;D) by spores

Accepted Answer

The answer of Trichomonas vaginalis causes trichomoniasis, which is common...

Question 14

The trade name of chloroquine is:&#10;A) Vibramycin&#10;B) Lariam&#10;C) Aralen&#10;D) Primaquine

Accepted Answer

The answer of The trade name of chloroquine is:&#10;A) Vibramycin&#10;B)...

Question 15

The most common drug used for the prophylaxis and treatment of acute malarial attacks is:&#10;A) doxycycline&#10;B) chloroquine&#10;C) primaquine&#10;D) quinine

Accepted Answer

The answer of The most common drug used for the...

Question 16

The trade name of iodoquinol is:&#10;A) Yodoxin&#10;B) Tindamax&#10;C) Flagyl&#10;D) Paromomycin sulfate

Accepted Answer

The answer of The trade name of iodoquinol is:&#10;A) Yodoxin&#10;B)...

Question 17

Yodoxin is classified as:&#10;A) antiprotozoal, anti-malarial&#10;B) anti-infective, antiamebicide, antidepressant&#10;C) anti-malarial, antiviral, antacid&#10;D) antiamebicide, antiprotozoal, anti-infective

Accepted Answer

The answer of Yodoxin is classified as:&#10;A) antiprotozoal, anti-malarial&#10;B) anti-infective,...

Question 18

Paromomycin is a broad-spectrum antibiotic that works very similarly to:&#10;A) neomycin&#10;B) tetracycline&#10;C) tinidazole&#10;D) nitazoxanide

Accepted Answer

The answer of Paromomycin is a broad-spectrum antibiotic that works...

Question 19

The trade name of nitazoxanide is:&#10;A) Tinidazole&#10;B) Alinia&#10;C) Flagyl&#10;D) Tindamax

Accepted Answer

The answer of The trade name of nitazoxanide is:&#10;A) Tinidazole&#10;B)...

Question 20

The treatment of choice for severe Plasmodium falciparum is:&#10;A) doxycycline&#10;B) primaquine&#10;C) quinine&#10;D) chloroquine

Accepted Answer

The answer of The treatment of choice for severe Plasmodium...

Question 21

Aplastic anemia and alopecia are the adverse effects of which of the following drugs?&#10;A) chloroquine&#10;B) hydroxychloroquine&#10;C) doxycycline&#10;D) mefloquine

Accepted Answer

The answer of Aplastic anemia and alopecia are the adverse...

Question 22

Primaquine is contraindicated in patients with:&#10;A) lupus erythematosus&#10;B) asthma&#10;C) urinary tract infections&#10;D) sinusitis

Accepted Answer

The answer of Primaquine is contraindicated in patients with:&#10;A) lupus...

Question 23

Pyrimethamine is used to treat acute malaria and:&#10;A) Chagas disease&#10;B) amebiasis&#10;C) toxoplasmosis&#10;D) giardia

Accepted Answer

The answer of Pyrimethamine is used to treat acute malaria...

Question 24

The trade name of metronidazole is:&#10;A) Tindamax&#10;B) Yodoxin&#10;C) Alinia&#10;D) Flagyl

Accepted Answer

The answer of The trade name of metronidazole is:&#10;A) Tindamax&#10;B)...

Question 25

Which of the following drugs is used to treat giardiasis in patients 1 year of age and older?&#10;A) nitazoxanide&#10;B) pyrimethamine&#10;C) benznidazole&#10;D) nifurtimox

Accepted Answer

The answer of Which of the following drugs is used...

Question 26

Chagas disease is caused by:&#10;A) Giardia lamblia&#10;B) Entamoeba histolytica&#10;C) Toxoplasma gondii&#10;D) Trypanosoma cruzi

Accepted Answer

The answer of Chagas disease is caused by:&#10;A) Giardia lamblia&#10;B)...

Question 27

Abdominal cramps with eructation and foul-smelling diarrhea are symptoms of:&#10;A) malaria&#10;B) giardiasis&#10;C) amebiasis&#10;D) toxoplasmosis

Accepted Answer

The answer of Abdominal cramps with eructation and foul-smelling diarrhea...

Question 28

All patients taking pyrimethamine should also receive: A) folinic acid B) vitamin B₆ C) vitamin B₁₂ D) vitamin E

Accepted Answer

The answer of All patients taking pyrimethamine should also receive:&#10;A)...

Question 29

The trade name of nifurtimox is:&#10;A) Flagyl&#10;B) Alinia&#10;C) Fasigyn&#10;D) none; it is generic only

Accepted Answer

The answer of The trade name of nifurtimox is:&#10;A) Flagyl&#10;B)...

Question 30

A severe complication of congenital toxoplasmosis is:&#10;A) encephalitis&#10;B) pancreatitis&#10;C) blindness&#10;D) retrograde amnesia

Accepted Answer

The answer of A severe complication of congenital toxoplasmosis is:&#10;A)...

Deck 19: Antiprotozoal Agents