Deck 11: Drug Therapy for the Musculoskeletal System

Question 1

Long-term use of muscle relaxants is required for all of the following conditions, except:

A) cerebral palsy
B) multiple sclerosis
C) anencephaly
D) stroke

Answer 1

anencephaly

Question 2

Neuromuscular blocking agents are able to block the action of:

A) serotonin
B) epinephrine
C) dopamine
D) acetylcholine

Answer 2

acetylcholine

Question 3

The principal use of neuromuscular blocking drugs is to provide:

A) reduction in various types of spasms
B) adequate skeletal muscular relaxation during surgery
C) adequate hyperthermia during surgery
D) adequate pain control after an injury

Answer 3

adequate skeletal muscular relaxation during surgery

Question 4

Which of the following is the exact mechanism of centrally acting muscle relaxants?

A) They interfere with neuromuscular transmission of muscles.
B) They suppress inflammation in acute forms of arthritis.
C) They block the formation of uric acid.
D) It is unknown.

Question 5

Acetylcholine is broken down by acetylcholinesterase, which results in:

A) contraction
B) relaxation
C) oxidation
D) hydration

Question 6

Which of the following centrally acting agents is often the drug of first choice because of its wide safety margin?

A) chlorzoxazone
B) methocarbamol
C) diazepam
D) baclofen

Question 7

Which of the following is an example of direct-acting antispasmodic drugs?

A) botulinum toxins
B) doxacurium
C) succinylcholine
D) tubocurarine

Question 8

Quinine sulfate is an antimalarial drug that is used for:

A) congenital tonic spasms
B) congenital heart diseases
C) nocturnal leg cramps
D) A and C

Question 9

Which of the following drugs may color the urine orange to red?

A) quinine
B) niacin
C) dantrolene
D) penicillin

Question 10

Which of the following drugs should be used cautiously in patients with impaired cardiac function, pulmonary dysfunction, or in patients younger than 35 years of age (especially women)?

A) dantrolene
B) diazepam
C) methotrexate
D) chlorzoxazone

Question 11

Dantrolene is used to treat which of the following disorders?

A) multiple sclerosis
B) myocardial infarction
C) stroke
D) A and C

Question 12

Penicillamine is a chelating drug that is a metabolite of:

A) barbiturates
B) gold compounds
C) penicillins
D) corticosteroids

Question 13

Corticosteroids are used in severe, progressive cases of which of the following disorders?

A) peptic ulcer
B) rheumatoid arthritis
C) hypertension
D) hepatitis

Question 14

Colchicine is the traditional drug of choice for which of the following disorders?

A) pulmonary hypertension
B) acute ophthalmoplegia
C) acute hepatitis C
D) acute gout attack

Question 15

Penicillamine is classified as which of the following types of drugs?

A) antihypertensive
B) anti-inflammatory
C) antibacterial
D) antiarrhythmic

Question 16

Neuromuscular blocking drugs may be used to decrease the severity of muscle contractions during:

A) electroconvulsive treatment
B) electrocardiogram procedures
C) electroencephalography
D) elective surgery

Question 17

The peak incidence of rheumatoid arthritis among women is between which of the following ages?

A) 15 to 20 years of age
B) 20 to 30 years of age
C) 30 to 40 years of age
D) 40 to 60 years of age

Question 18

Which of the following are the most common causes of injury in people 65 years of age or older?

A) sports injuries
B) high-speed motor accidents
C) falls
D) all of the above

Question 19

The most common site of the initial gouty attack is:

A) the first metacarpal joint
B) the first metatarsophalangeal joint
C) the first phalangeal joint
D) none of the above

Question 20

Colchicine is most effective when initiated how many hours after the symptoms of gout begin?

A) 1 to 2 hours
B) 5 to 10 hours
C) 12 to 36 hours
D) 48 to 72 hours

Question 21

Gout often affects a single joint, such as in the ____________________.

Question 22

Neuromuscular blocking agents have been used in the management of tetanus, and for various ____________________ disorders.

Question 23

Spinal involvement of rheumatoid arthritis usually is limited to the ____________________ region.

Question 24

Slow-acting antirheumatic drugs may be prescribed for patients with ____________________ that progress to deformity.

Question 25

A complete tear in a muscle or tendon is described as a ____________________.

Question 26

Skeletal muscle allows __________ movement such as flexion and extension of the legs.

Question 27

The articular system consists of three thypes of joints which includes synarthrosis, amphiarthrosis, and __________.

Question 28

An example of an amphiarthrosis joint is the __________ __________.

Question 29

Collection of blood in organs, spaces, or tissues is called __________.

Question 30

Skeletal muscle relaxants work by __________ somatic motor nerve impulses through depression of the neurons within the central nervous system.

Question 31

Some neuromuscular agents occupy a receptor site on the motor end plate and block the action of __________.

Question 32

The short-acting neuromuscular blocking drugs are used to relax the __________ muscles during endotracheal intubation.

Question 33

Neuromuscular blocking drugs are not safe during pregnancy, lactation, or in children younger than __________ years.

Question 34

The centrally acting muscle relaxants may be used to reduce muscle spasms in patients with __________ __________, multiple sclerosis, and spinal cord injury.

Question 35

Direct-acting skeletal muscle relaxants have no effect on __________ or cardiac muscles.

Question 36

Dantrolene is used to treat malignant __________.

Question 37

Dantrolene may color the urine orange to __________.

Question 38

Gold compounds prevent inflammation in active forms of __________.

Question 39

Colchicine is most effective when initiated __________ to __________ hours after symptoms of gout begin.

Question 40

Allopurinol is used in the treatment of gout and primary uric acid __________.

Question 41

Match the generic name with the trade name.

-botulinum toxin type A

A)Depen
B)Azulfindine
C)Myabloc
D)Botox
E)Plaquenil

Question 42

Match the generic name with the trade name.

-botulinum toxin type B

A)Depen
B)Azulfindine
C)Myabloc
D)Botox
E)Plaquenil

Question 43

Match the generic name with the trade name.

-hydrochloroquine

A)Depen
B)Azulfindine
C)Myabloc
D)Botox
E)Plaquenil

Question 44

Match the generic name with the trade name.

-penicillamine

A)Depen
B)Azulfindine
C)Myabloc
D)Botox
E)Plaquenil

Question 45

Match the generic name with the trade name.

-sulfasalazine

A)Depen
B)Azulfindine
C)Myabloc
D)Botox
E)Plaquenil

Question 46

Match the generic name with the trade name.

-succinylcholine

A)Zemuron
B)Lioresal
C)Nimbex
D)Flexeril
E)Anectine

Question 47

Match the generic name with the trade name.

-cyclobenzapine

A)Zemuron
B)Lioresal
C)Nimbex
D)Flexeril
E)Anectine

Question 48

Match the generic name with the trade name.

-rocuronium

A)Zemuron
B)Lioresal
C)Nimbex
D)Flexeril
E)Anectine

Question 49

Match the generic name with the trade name.

-baclofen

A)Zemuron
B)Lioresal
C)Nimbex
D)Flexeril
E)Anectine

Question 50

Match the generic name with the trade name.

-cisatracurium

A)Zemuron
B)Lioresal
C)Nimbex
D)Flexeril
E)Anectine