Deck 8: Topical Anesthetics

Question 1

Match the following:

-Benzocaine

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Answer 1

Common ester

Question 2

Match the following:

-Cetacaine

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Answer 2

Benzocaine, butamben, and tetracaine

Question 3

Match the following:

-Compounded

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Answer 3

Formulated

Question 4

Match the following:

-Dyclonine

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Question 5

Match the following:

-Jet injector

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Question 6

Match the following:

-Lidocaine

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Question 7

Match the following:

-Methylparaben

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Question 8

Match the following:

-Oraqix

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Question 9

Match the following:

-Para-aminobenzoic acid

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Question 10

Match the following:

-Tetracaine

A) Formulated
B) Benzocaine, butamben, and tetracaine
C) Common ester
D) Preservative
E) Ketone
F) Air propelled
G) Most potent topical
H) Subgingival placement
I) Metabolite
J) Common amide

Question 11

The variety of application methods for topical anesthetic drugs complicates the safety of their use.

Question 12

Benzocaine topical exists nearly 100% in the base form and is poorly absorbed into the systemic circulation.

Question 13

The most common concentration of benzocaine topical is 20%, which will provide a 30 second onset of anesthesia with peak effectiveness in approximately 2 minutes.

Question 14

Compared to injectable local anesthetic drugs, topical products do not require MRDs because they are potentially less toxic.

Question 15

Benzocaine topical can induce methemoglobinemia.

Question 16

Precautions for toxicity increase when topical anesthetic is applied to abraded tissue.

Question 17

Cetacaine is a eutectic mixture of lidocaine, butamben, and tetracaine.

Question 18

The advantages of Cetacaine are its low risk of allergy, rapid onset, and long duration of anesthesia.

Question 19

Compounding rules for topical anesthetics allow multidose packaging for use with multiple patients.

Question 20

Topical anesthetics are most commonly used ________.

Question 21

The onset of action for benzocaine is ________.

Question 22

The duration of action for benzocaine is up to ________.

Question 23

A ________ topical anesthetic is a liquid at room temperature and a gel when placed in the gingival sulcus.

Question 24

Benzocaine is available in a range of ________ to ________ % formulations.

Question 25

The FDA pregnancy category for benzocaine is _______.

Question 26

Overdose reactions from lidocaine topical are similar to injectable forms with progression to CNS ________ without the initial excitation phase.

Question 27

A combination of anesthetic drugs is known as a ________.

Question 28

Three ester drugs, benzocaine, butamben, and tetracaine are formulated together in ________ topical anesthetic.

Question 29

Which of the following is not an indication for topical anesthetic drugs in dentistry?

A) Needle penetration
B) Radiographic film placement
C) Periodontal evaluation
D) Sedation

Question 30

Which of the following application methods are considered safest when preventing toxicity?

A) Metered sprays and single dose application systems
B) Patches and metered sprays
C) Gels and liquids
D) Swabs and two-phase applications

Question 31

Which of the following does not contribute to the toxicity risk of topical anesthetic drugs?

A) Hydrophilic properties
B) Higher concentrations
C) Total applied dose
D) Application method

Question 32

Why do topical anesthetics require a higher concentration of drug than the same drug used as an injectable local anesthetic?

A) More base molecules of drug are needed to diffuse through membranes barriers
B) They are less likely to produce toxicity when applied topically
C) Decreased amounts are applied topically than when locally injected
D) They do not contain vasoconstrictors

Question 33

Which of the following is not a typical sign of CNS toxicity related to overdoses of topical anesthetic drugs?

A) Shaking and agitation
B) Talkativeness and excitedness
C) Disorientation and drowsiness
D) Loss of consciousness

Question 34

Which of the following topical anesthetic drugs is a eutectic mixture?

A) Dyclonine hydrochloride
B) Benzocaine
C) Cetacaine
D) Butamben

Question 35

Which of the following eutectic mixtures is available as an intrapocket topical anesthesia?

A) Lidocaine
B) Oraqix
C) Cetacaine
D) EMLA

Question 36

Which of the following is not a benefit of eutectic mixtures of anesthetic drugs for use in dentistry?

A) Greater depth of penetration on mucosa
B) Higher concentrations of base forms of anesthetics
C) Increased therapeutic range
D) Typical pulpal anesthesia

Question 37

Oraqix is a eutectic mixture of which anesthetic drugs?

A) Benzocaine and lidocaine
B) Lidocaine and cetacaine
C) Prilocaine and lidocaine
D) Prilocaine and benzocaine

Question 38

All of the following statements are true regarding compounded drugs, except:

A) Compounded drugs are formulated for individuals for whom they are prescribed.
B) Compounded drugs may be used on other individuals as long as the use is the same as the original use.
C) Compounded drugs may contain much larger quantities of drug compared to multiuse commercial preparations.
D) Compounded topicals are dispensed by prescription.

Question 39

List uses for topical anesthetic drugs in dentistry.

Question 40

Why it is difficult to determine the administered dose of topical anesthetics drugs?

Question 41

Describe the local adverse reactions to topical local anesthetic agents.

Question 42

Identify symptoms of a systemic overdose of topical anesthetic drugs.

Question 43

Discuss the safety features of Oraqix.