Deck 27: Drugs for Immune System Modulation

Question 1

Which of the following can be antigens? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

A) Pollen,
B) Bacteria
C) Viruses
D) Cancerous cells

Answer 1

Pollen,
Bacteria
Viruses
Cancerous cells

Question 2

T cells produce huge amounts of these chemicals that regulate important aspects of the immune response. These chemicals are called:

A) B cells
B) Cytokines
C) Helper T cells
D) Antibodies

Answer 2

Cytokines

Question 3

What is the recommendation in Canada for human papillomavirus (HPV) immunization?

A) For adults older than 60 years or may be used in 50 to 59 years
B) All adults every 10 years preferably with tetanus toxoid (Td) or pertussis (Tdap)
C) Females under 45 years of age and males under 26 years not previously immunized
D) All born after 1970; high risk born before 1970.

Answer 3

Females under 45 years of age and males under 26 years not previously immunized

Question 4

Examples of biologic response modifiers would include (Select all that apply.): Note: Credit will be given only if all correct choices and no incorrect choices are selected.

A) IFNs
B) ILs
C) CSFs
D) Antibiotics

Question 5

This is the most common IFN

A) Bacillus Calmette-Guérin (BCG) vaccine
B) IFN-alfa-2b
C) CSFs
D) IFN-beta

Question 6

Drug classes that have immunosuppressant activity include (Select all that apply):
Note: Credit will be given only if all correct choices and no incorrect choices are selected.

A) corticosteroids (glucocorticoids),
B) antimetabolites
C) monoclonal antibodies
D) calcineurin inhibitors

Question 7

Teaching parents the importance of maintaining up-to-date vaccinations is a dynamic responsibility for the pharmacist. What should the pharmacist stress the importance of when teaching about vaccinations?

A) Treating illness
B) The school pharmacist
C) Health departments
D) Preventing illness

Question 8

The pharmacist is caring for a patient who has been prescribed an interferon. What effect does the pharmacist anticipate this medication will have on the patient? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

A) Anti-inflammatory action
B) Decrease the heart rate
C) Slow the spread of viral infections
D) Decrease the blood pressure
E) Increase blood glucose

Question 9

A pharmacist is teaching her patient about cyclosporine therapy following a recent liver transplant. What statement by the patient indicates further teaching is needed?

A) "I might experience a decrease in urinary flow."
B) "I can take acetaminophen (Tylenol) for a headache, but I have to be very careful."
C) "I can take this drug with any fluid as long as it is at the same time every day."
D) "I will need to come into the clinic for periodic blood counts."

Question 10

The innate defences are nonspecific so the protection is the same regardless of the pathogen.

Question 11

Unlike T cells, B cells do not produce antibodies.

Question 12

Administration of vaccine or exposure to an antigen stimulates the body to produce antibodies and memory cells. This is called passive immunity.

Question 13

The biological response modifiers are administered to boost certain functions of the immune system.

Question 14

Immunosuppressants are medications given to lessen the immune response after transplantation and, in some cases, they are continued indefinitely at low doses.

Question 15

Infliximab is used to suppress the severe inflammation that often accompanies autoimmune disorders such as Crohn's disease and rheumatoid arthritis.

Question 16

Azathioprine is an example of a biologic response modifier.

Question 17

List the steps in humoral and cell-mediated immunity.

Question 18

Give examples of innate body defenses and their purpose.

Question 19

Describe an herbal remedy used to boost your immune system.