Deck 10: Immunology

Question 1

A cell expressing $CD3^+, CD25^+$ , and FoxP31 is a

A) $(\gamma\gamma)$ T cell
B)Helper T cell
C)Cytotoxic T cell
D)Regulatory T cell
E)Natural killer T cell

Answer 1

Regulatory T cell

Question 2

A T cell located at the epithelial barrier of the gut is a

A) $(\gamma\gamma)$ T cell
B)Helper T cell
C)Cytotoxic T cell
D)Regulatory T cell
E)Natural killer T cell

Answer 2

$(\gamma\gamma)$ T cell

Question 3

A $CD3^+$ cell that is CD1 restricted to glycolipids is a

A) $(\gamma\gamma)$ T cell
B)Helper T cell
C)Cytotoxic T cell
D)Regulatory T cell
E)Natural killer T cell

Answer 3

Natural killer T cell

Question 4

A $CD3^+$ cell that secretes perforin and granzyme is a

A) $(\gamma\gamma)$ T cell
B)Helper T cell
C)Cytotoxic T cell
D)Regulatory T cell
E)Natural killer T cell

Question 5

A $CD3^+$ cell that secretes IL-2 when activated is a

A) $(\gamma\gamma)$ T cell
B)Helper T cell
C)Cytotoxic T cell
D)Regulatory T cell
E)Natural killer T cell

Question 6

A product of vaccination is

A)B-1 cells
B)Naïve mature B cells
C)Centrocytes
D)Memory B cells
E)Plasma cells

Question 7

A cell that secretes antibodies that recognize polysaccharides is a

A)B-1 cell
B)Naïve mature B cell
C)Centrocyte
D)Memory B cell
E)Plasma cell

Question 8

A cell performing somatic hypermutation is a

A)B-1 cell
B)Naïve mature B cell
C)Centrocyte
D)Memory B cell
E)Plasma cell

Question 9

A cell that secretes large quantities of antibody but does not express surface immunoglobulin is a

A)B-1 cell
B)Naïve mature B cell
C)Centrocyte
D)Memory B cell
E)Plasma cell

Question 10

A cell that expresses both IgM and IgD on the cell surface is a

A)B-1 cell
B)Naïve mature B cell
C)Centrocyte
D)Memory B cell
E)Plasma cell

Question 11

A cell that resides in the liver and is a part of the reticulo-endothelial system is a

A)M1 macrophage
B)M2 macrophage
C)Kupffer cell
D)Foam cell
E)Giant cell

Question 12

A cell directed by IL-4 to promote tissue repair, angiogenesis, and tumor growth is a

A)M1 macrophage
B)M2 macrophage
C)Kupffer cell
D)Foam cell
E)Giant cell

Question 13

A cell derived from monocytes that attach to the arterial intima and accumulate lipids is a

A)M1 macrophage
B)M2 macrophage
C)Kupffer cell
D)Foam cell
E)Giant cell

Question 14

A cell directed by IFN $\gamma$ to promote ROS production and cytolysis is a

A)M1 macrophage
B)M2 macrophage
C)Kupffer cell
D)Foam cell
E)Giant cell

Question 15

A syncytial cell found within granuloma is a

A)M1 macrophage
B)M2 macrophage
C)Kupffer cell
D)Foam cell
E)Giant cell

Question 16

A cell that secretes IL-4, temporarily resides in draining lymph nodes, and promotes the $T_h2$ response is a

A)Neutrophil
B)Basophil
C)Eosinophil
D)Plasmacytoid cell
E)Mast cell

Question 17

A short-lived phagocytic cell recruited to inflammatory sites by macrophage secretion of CCL8 is a

A)Neutrophil
B)Basophil
C)Eosinophil
D)Plasmacytoid cell
E)Mast cell

Question 18

A tissue resident cell that responds to PAMPs and releases histamine and eicosanoids is a

A)Neutrophil
B)Basophil
C)Eosinophil
D)Plasmacytoid cell
E)Mast cell

Question 19

A cell found in the circulation that secretes INF $\alpha$ and INF $\beta$ is a

A)Neutrophil
B)Basophil
C)Eosinophil
D)Plasmacytoid cell
E)Mast cell

Question 20

A cell expressing Fc? receptors and recruited to sites of helminth infections is a

A)Neutrophil
B)Basophil
C)Eosinophil
D)Plasmacytoid cell
E)Mast cell

Question 21

A pro-inflammatory cytokine with a major role in asthma is a

A)INF- $\gamma$
B)IL-4
C)IL-6
D)IL-10
E)IL-17

Question 22

A cytokine that promotes humoral immunity and is produced by $T_h2$ cells is a

A)INF- $\gamma$
B)IL-4
C)IL-6
D)IL-10
E)IL-17

Question 23

A cytokine that promotes cell-mediated immunity and is produced by $T_h1$ cells is a

A)INF- $\gamma$
B)IL-4
C)IL-6
D)IL-10
E)IL-17

Question 24

An anti-inflammatory cytokine is a

A)INF- $\gamma$
B)IL-4
C)IL-6
D)IL-10
E)IL-17

Question 25

A cytokine produced by macrophage to induce liver production of acute phase proteins is a

A)INF- $\gamma$
B)IL-4
C)IL-6
D)IL-10
E)IL-17

Question 26

A cell producing cytotoxic compounds following $T_h1$ cell activation is a(n)

A)Immature myeloid-derived dendritic cell
B)Mature myeloid-derived dendritic cell
C)Follicular dendritic cell
D)B cell
E)Macrophage

Question 27

A cell expressing cell surface MHC Class II, CD80/88 and secretes IL-12 is a(n)

A)Immature myeloid-derived dendritic cell
B)Mature myeloid-derived dendritic cell
C)Follicular dendritic cell
D)B cell
E)Macrophage

Question 28

A cell captured by endocytosis using transmembrane immunoglobulin is a(n)

A)Immature myeloid-derived dendritic cell
B)Mature myeloid-derived dendritic cell
C)Follicular dendritic cell
D)B cell
E)Macrophage

Question 29

A cell with a majority of MHC Class II located within intracellular compartments is a(n)

A)Immature myeloid-derived dendritic cell
B)Mature myeloid-derived dendritic cell
C)Follicular dendritic cell
D)B cell
E)Macrophage

Question 30

An epithelial-derived cell expressing cell surface C3-antigen is a

A)Immature myeloid-derived dendritic cell
B)Mature myeloid-derived dendritic cell
C)Follicular dendritic cell
D)B cell
E)Macrophage