Deck 47: Animal Development

Question 1

The vitelline layer of the sea urchin egg

A)is outside of the fertilization membrane.
B)releases calcium, which initiates the cortical reaction.
C)has receptor molecules that are specific for binding acrosomal proteins.
D)is first visible only when organogenesis is nearly completed.
E)is a mesh of proteins crossing through the cytosol of the egg.

Answer 1

C

Question 2

In sea urchins,the "fast block" and the longer-lasting "slow block" to polyspermy,respectively,are

A)the acrosomal reaction and the formation of egg white.
B)the cortical reaction and the formation of yolk protein.
C)the jelly coat of the egg and the vitelline membrane.
D)membrane depolarization and the cortical reaction.
E)inactivation of the sperm acrosome.

Answer 2

D

Question 3

In mammals,the nuclei resulting from the union of the sperm and the egg are first truly diploid at the end of the

A)acrosomal reaction.
B)completion of spermatogenesis.
C)initial cleavage.
D)activation of the egg.
E)completion of gastrulation.

Answer 3

C

Question 4

The structure of the Drosophila gene called Tinman is similar to a gene in humans that also

A)promotes ear development.
B)specifies the location of the heart.
C)determines structures in the eyes.
D)specifies limb elongation points.
E)filters lymphatic fluid.

Question 5

Contact of a sperm with signal molecules in the coat of an egg causes the sperm to undergo

A)mitosis.
B)depolarization.
C)apoptosis.
D)vitellogenesis.
E)the acrosomal reaction.

Question 6

The formation of the fertilization membrane requires an increase in the availability of

A)bicarbonate ions.
B)calcium ions.
C)hydrogen ions.
D)potassium ions.
E)sodium ions.

Question 7

In an egg cell treated with EDTA,a chemical that binds calcium and magnesium ions,the

A)acrosomal reaction would be blocked.
B)fusion of sperm and egg nuclei would be blocked.
C)fast block to polyspermy would not occur.
D)fertilization envelope would not be formed.
E)zygote would not contain maternal and paternal chromosomes.

Question 8

From earliest to latest,the overall sequence of early development proceeds in which of the following sequences?

A)first cell division → synthesis of embryo's DNA begins → acrosomal reaction → cortical reaction
B)cortical reaction → synthesis of embryo's DNA begins → acrosomal reaction → first cell division
C)cortical reaction → acrosomal reaction → first cell division → synthesis of embryo's DNA begins
D)first cell division → acrosomal reaction → synthesis of embryo's DNA begins → cortical reaction
E)acrosomal reaction → cortical reaction → synthesis of embryo's DNA begins → first cell division

Question 9

The cortical reaction functions directly in the

A)formation of a fertilization envelope.
B)production of a fast block to polyspermy.
C)release of hydrolytic enzymes from the sperm cell.
D)generation of a nerve-like impulse by the egg cell.
E)fusion of egg and sperm nuclei.

Question 10

In mammalian eggs,the receptors for sperm are found in the

A)fertilization membrane.
B)zona pellucida.
C)cytosol of the egg.
D)nucleus of the egg.
E)mitochondria of the egg.

Question 11

Even in the absence of sperm,metabolic activity in an egg can be artificially activated by

A)abnormally high levels of carbonic acid in the cytosol.
B)abnormally low levels of extracellular oxygen.
C)injection of calcium ions into the cytosol.
D)exposure to the low pH of the uterus.
E)depletion of its ATP supplies.

Question 12

A reproductive difference between sea urchins and humans is

A)the sea urchin egg completes meiosis prior to fertilization, but meiosis in humans is completed after fertilization.
B)sea urchin eggs are produced by meiosis, but human eggs are produced by mitosis.
C)sea urchin eggs and sperm are of equal size, but human eggs are much bigger than human sperm.
D)sea urchins, but not humans, have a need to block polyspermy because only in sea urchins can there be more than one source of sperm to fertilize the eggs.
E)sea urchin zygotes get their mitochondria from the sperm but human zygotes get their mitochondria from the egg.

Question 13

Fertilization normally

A)reinstates diploidy.
B)follows gastrulation.
C)is required for parthenogenesis.
D)merges two diploid cells into one haploid cell.
E)precedes ovulation.

Question 14

During fertilization,the acrosomal contents

A)block polyspermy.
B)help propel more sperm toward the egg.
C)digest the protective jelly coat on the surface of the egg.
D)nourish the mitochondria of the sperm.
E)trigger the completion of meiosis by the sperm.

Question 15

Fertilization of an egg without activation is most like

A)placing the key in the ignition of a car but not starting the engine.
B)resting during halftime of a basketball game.
C)preparing a pie from scratch and baking it in the oven.
D)walking to the cafeteria and eating lunch.
E)dropping a rock off a cliff and watching it land in the valley below.

Question 16

A human zygote undergoes its first cell division

A)5 seconds after fertilization.
B)30 minutes after fertilization.
C)90 minutes after fertilization.
D)4 hours after fertilization.
E)24 hours after fertilization.

Question 17

As an embryo develops,new cells are produced as the result of

A)differentiation.
B)preformation.
C)cell division.
D)morphogenesis.
E)epigenesis.

Question 18

A sea urchin zygote undergoes its first cell division

A)5 seconds after fertilization.
B)30 minutes after fertilization.
C)90 minutes after fertilization.
D)4 hours after fertilization.
E)24 hours after fertilization.

Question 19

Contact of a sea urchin egg with signal molecules on sperm causes the egg to undergo a brief

A)mitosis.
B)membrane depolarization.
C)apoptosis.
D)vitellogenesis.
E)acrosomal reaction.

Question 20

In a newly fertilized egg,the vitelline layer

A)opens the egg's nuclear membrane to allow haploid sperm DNA to enter.
B)hardens to form a protective cover.
C)secretes hormones that enhance steroidogenesis by the ovary.
D)reduces the loss of water from the egg and prevents desiccation.
E)provides most of the nutrients used by the zygote.

Question 21

Among these choices,the largest cell involved in frog reproduction is

A)the spermatozoon.
B)the ovum.
C)a blastomere in the vegetal pole.
D)a blastomere in the animal pole.
E)one of the products of the first cleavage.

Question 22

The vegetal pole of the zygote differs from the animal pole in that

A)the vegetal pole has a higher concentration of yolk.
B)the blastomeres originate only in the vegetal pole.
C)the posterior end of the embryo forms at the vegetal pole.
D)the vegetal pole cells undergo mitosis but not cytokinesis.
E)the polar bodies bud from this region.

Question 23

The yolk of the frog egg

A)prevents gastrulation.
B)is concentrated at the animal pole.
C)is homogeneously arranged in the egg.
D)impedes the formation of a primitive streak.
E)supports the higher rate of cleavage at the animal pole compared to the vegetal pole.

Question 24

A human blastomere is

A)an embryonic cell that is much smaller than the ovum.
B)an embryonic structure that includes a fluid-filled cavity.
C)that part of the acrosome that opens the egg's membrane.
D)a component of the zona pellucida.
E)a cell that contains a (degenerating)second polar body.

Question 25

The first cavity formed during sea urchin development is the

A)blastopore.
B)mouth.
C)blastocoel.
D)anus.
E)blastomere.

Question 26

An embryo with meroblastic cleavage,extraembryonic membranes,and a primitive streak must be that of

A)an insect.
B)a fish.
C)an amphibian.
D)a bird.
E)a sea urchin.

Question 27

Compared to sea urchin eggs,those of mammals

A)complete the fertilization process more rapidly.
B)have not already completed meiosis at the time of ovulation.
C)have a more distinct animal pole.
D)have a more distinct vegetal pole.
E)have no requirement for the cortical reaction.

Question 28

The least amount of yolk would be found in the egg of a

A)bird.
B)fish.
C)frog.
D)eutherian (placental)mammal.
E)reptile.

Question 29

Cells move to new positions as an embryo establishes its three germ tissue layers during

A)determination.
B)cleavage.
C)fertilization.
D)induction.
E)gastrulation.

Question 30

As cleavage continues during frog development,the size of the blastomeres

A)increases as the number of the blastomeres decreases.
B)increases as the number of the blastomeres increases.
C)decreases as the number of the blastomeres increases.
D)decreases as the number of the blastomeres decreases.
E)increases as the number of the blastomeres stays the same.

Question 31

In a developing frog embryo,most of the yolk is

A)located near the animal pole.
B)located near the vegetal pole.
C)found within the cleavage furrow.
D)found within the blastocoels.
E)distributed equally throughout the embryo.

Question 32

The cortical reaction occurs in which animals?

A)birds and reptiles
B)sea urchins, mammals, and fishes
C)amphibians, birds, and invertebrates
D)mammals and invertebrates
E)birds and fishes

Question 33

The pattern of embryonic development in which only the cells lacking yolk subsequently undergo cleavage is called

A)arcadian development, which is typical of insects.
B)holoblastic development, which is typical of marsupial mammals.
C)meroblastic development, which is typical of humans.
D)holoblastic development, which is typical of amphibians.
E)meroblastic development, which is typical of birds.

Question 34

Meroblastic cleavage occurs in

A)sea urchins, but not humans or birds.
B)humans, but not sea urchins or birds.
C)birds, but not sea urchins or humans.
D)both sea urchins and birds, but not humans.
E)both humans and birds, but not sea urchins.

Question 35

Which of these animals is a diploblast?

A)jellyfish
B)sea urchin
C)frog
D)chick
E)fruit fly

Question 36

The small portion of the embryo that will become its dorsal side develops from the

A)morula.
B)primitive streak.
C)archenteron.
D)grey crescent.
E)blastocoel.

Question 37

At the moment of sperm penetration,human eggs

A)have used flagellar propulsion to move from the ovary to the oviduct.
B)accept as many sperm as possible in order to select the one with the highest fertility.
C)are still located within the ovary.
D)have a paper-thin cell of calcium carbonate that prevents desiccation.
E)are still surrounded by follicular cells.

Question 38

To meet a zygote's metabolic and developmental requirements

A)maternal RNA and maternal proteins must be present.
B)paternal RNA and maternal proteins must be present.
C)the haploid DNA in the nucleus must be transcribed.
D)the nucleus must have hundreds of copies of every gene, allowing a high rate of gene expression.
E)the zygote must continuously undergo endocytosis of proteins to take them from its environment.

Question 39

During the early part of the cleavage stage in frog development,the rapidly developing cells

A)skip the mitosis phase of the cell cycle.
B)skip the S phase of the cell cycle.
C)skip the G₁ and G₂ phases of the cell cycle.
D)rapidly increase the volume and mass of the embryo.
E)skip the cytokinesis phase of the cell cycle.

Question 40

If gastrulation were blocked by an environmental toxin,then

A)cleavage would not occur in the zygote.
B)embryonic germ layers would not form.
C)fertilization would be blocked.
D)the blastula would not be formed.
E)the blastopore would form above the grey crescent in the animal pole.

Question 41

At the time of implantation,the human embryo is called a

A)blastocyst.
B)gastrula.
C)fetus.
D)somite.
E)zygote.

Question 42

Although it contributes no cells to the embryo,the formation of the primitive streak is guided by the structure known as the

A)endoderm.
B)mesoderm.
C)ectoderm.
D)neural crest.
E)hypoblast.

Question 43

Thalidomide,now banned for use as a sedative in pregnancy,was used in the early 1960s by many women in their first trimester of pregnancy.Some of these women gave birth to children with arm and leg deformities,suggesting that the drug most likely influenced

A)early cleavage divisions.
B)determination of the polarity of the zygote.
C)differentiation of bone tissue.
D)morphogenesis.
E)organogenesis.

Question 44

The archenteron of the developing frog eventually develops into the

A)reproductive organs.
B)blastocoel.
C)heart and lungs.
D)digestive tract.
E)brain and spinal cord.

Question 45

A primitive streak forms during the early embryonic development of

A)birds, but not frogs or humans.
B)frogs, but not birds or humans.
C)humans, but not birds or frogs.
D)birds and frogs, but not humans.
E)humans and birds, but not frogs.

Question 46

The vertebrate ectoderm is the origin of the

A)nervous system.
B)liver.
C)pancreas.
D)heart.
E)kidneys.

Question 47

The earliest developmental stage among these choices is

A)germ layers.
B)morula.
C)blastopore.
D)gastrulation.
E)invagination.

Question 48

Gases are exchanged in a mammalian embryo in the

A)amnion.
B)hypoblast.
C)chorion.
D)trophoblast.
E)yolk sac.

Question 49

Which of the following is a correct description of an anatomical relationship?

A)The mesoderm gives rise to the notochord.
B)The endoderm gives rise to the hair follicles.
C)The ectoderm gives rise to the liver.
D)The mesoderm gives rise to the lungs.

Question 50

In placental mammals,the yolk sac

A)transfers nutrients from the yolk to the embryo.
B)differentiates into the placenta.
C)becomes a fluid-filled sac that surrounds and protects the embryo.
D)produces blood cells that then migrate into the embryo.
E)stores waste products from the embryo until the placenta develops.

Question 51

From earliest to latest,the overall sequence of early development proceeds in which of the following sequences?

A)gastrulation → organogenesis → cleavage
B)ovulation → gastrulation → fertilization
C)cleavage → gastrulation → organogenesis
D)gastrulation → blastulation → neurulation
E)preformation → morphogenesis → neurulation

Question 52

Uterine implantation due to enzymatic digestion of the endometrium is initiated by the

A)inner cell mass.
B)endoderm.
C)chorion.
D)mesoderm.
E)trophoblast.

Question 53

Extraembryonic membranes develop in

A)mammals, but not birds or lizards.
B)birds, but not mammals or lizards.
C)lizards, but not mammals or birds.
D)mammals and birds, but not lizards.
E)mammals, birds, and lizards.

Question 54

The primitive streak in a bird is the functional equivalent of

A)the lip of the blastopore in the frog.
B)the archenteron in a frog.
C)polar bodies in a sea urchin.
D)the notochord in a mammal.
E)neural crest cells in a mammal.

Question 55

In a frog embryo,gastrulation

A)produces a blastocoel displaced into the animal hemisphere.
B)occurs along the primitive streak in the animal hemisphere.
C)is impossible because of the large amount of yolk in the ovum.
D)proceeds by involution as cells roll over the lip of the blastopore.
E)occurs within the inner cell mass that is embedded in the large amount of yolk.

Question 56

In all vertebrate animals,development requires

A)a large supply of yolk.
B)an aqueous environment.
C)extraembryonic membranes.
D)an amnion.
E)a primitive streak.

Question 57

In frog embryos,the blastopore becomes the

A)anus.
B)ears.
C)eyes.
D)nose.
E)mouth.

Question 58

An open space within the gastrula is the

A)ectoderm.
B)mesoderm.
C)archenteron.
D)endoderm.
E)neural crest cells.

Question 59

The migratory neural crest cells

A)form most of the central nervous system.
B)serve as precursor cells for the notochord.
C)form the spinal cord in the frog.
D)form neural and non-neural structures in the periphery.
E)form the lining of the lungs and of the digestive tract.

Question 60

The outer-to-inner sequence of tissue layers in a post-gastrulation vertebrate embryo is

A)endoderm → ectoderm → mesoderm.
B)mesoderm → endoderm → ectoderm.
C)ectoderm → mesoderm → endoderm.
D)ectoderm → endoderm → mesoderm.
E)endoderm → mesoderm → ectoderm.

Question 61

The term applied to a morphogenetic process whereby cells extend themselves,making the mass of the cells narrower and longer,is

A)convergent extension.
B)induction.
C)elongational streaming.
D)bi-axial elongation.
E)blastomere formation.

Question 62

In humans,identical twins are possible because

A)of the heterogeneous distribution of cytoplasmic determinants in unfertilized eggs.
B)of interactions between extraembryonic cells and the zygote nucleus.
C)of convergent extension.
D)early blastomeres can form a complete embryo if isolated.
E)the grey crescent divides the dorsal-ventral axis into new cells.

Question 63

Symptoms of Kartagener's syndrome include frequent sinus and bronchial infections,reversal of chest and abdominal organs,and afflicted males produce immotile sperm.This syndrome is a result of

A)deformation of the ZPA.
B)immotile cilia.
C)immotile flagella.
D)motile flagella.
E)motile cilia.

Question 64

Animal cells that are present only for a brief developmental phase will,following completion of that phase,undergo

A)diapause.
B)apoptosis
C)meiosis.
D)oxidative phosphorylation.
E)re-differentiation.

Question 65

Human trophoblasts

A)form the inner cell mass.
B)form from ectoderm.
C)are the precursors of the mesoderm.
D)are of embryonic origin and function in embryo nutrition.
E)are of maternal origin and function in embryo gas exchange.

Question 66

Changes in both cell shape and cell position occur extensively during

A)gastrulation, but not organogenesis or cleavage.
B)organogenesis, but not gastrulation or cleavage.
C)cleavage, but not gastrulation or organogenesis.
D)gastrulation and organogenesis, but not cleavage.
E)gastrulation, organogenesis, and cleavage.

Question 67

Syndactyly,a congenital abnormality in which webbing is present between fingers and toes,can be corrected after birth.In utero,the cells comprising the webbing failed to undergo

A)differentiation.
B)gastrulation.
C)apoptosis.
D)convergent extension.
E)morphogenesis.

Question 68

Two primary factors in shaping the polarity of the body axes in chick embryos are

A)light and temperature.
B)salt gradients and membrane potentials.
C)gravity and pH.
D)moisture and mucus.
E)location of sperm penetration and cortical reaction.

Question 69

Pregnant women are often advised to supplement their diet with folic acid to prevent neural tube defects such as those characteristic of

A)vestigial tails.
B)spina bifida.
C)herniated vertebral disks.
D)spinal stenosis.
E)spinal muscular atrophy.

Question 70

With regard to the establishment of an anterior-posterior axis,which of the following pairs is incorrect?

A)C) elegans - convergent elongation of P granules
B)mammal - orientation of egg and sperm nuclei before fusion
C)insects - morphogen gradients
D)frog - asymmetry in the animal vegetal hemispheres
E)chick - gravity as the egg travels down the oviduct

Question 71

What process is initiated in neurons that fail to make connections?

A)regeneration
B)apoptosis
C)oxidative phosphorylation
D)re-differentiation
E)invagination

Question 72

Hans Spemann and colleagues developed the concept of the primary organizer in amphibian embryos while studying the

A)medial cells between the optic cups.
B)anterior terminus of the notochord.
C)lateral margins of the neural tube.
D)posterior edge of the dorsal ectoderm.
E)dorsal lip of the blastopore.

Question 73

If an amphibian zygote is manipulated so that the first cleavage plane fails to divide the grey crescent,then

A)the daughter cell with the entire grey crescent will die.
B)both daughter cells will develop normally because amphibians are totipotent at this stage.
C)only the daughter cell with the grey crescent will develop normally.
D)both daughter cells will develop abnormally.
E)both daughter cells will die immediately.

Question 74

The arrangement of organs and tissues in their characteristic places in 3-D space defines

A)pattern formation.
B)induction.
C)differentiation.
D)determination.
E)organogenesis.

Question 75

Changes in the shape of a cell usually involve a reorganization of the

A)nucleus.
B)cytoskeleton.
C)extracellular matrix.
D)transport proteins.
E)nucleolus.

Question 76

The developmental precursors to the gonadal tissues of C.elegans uniquely contain

A)proteins of maternal origin.
B)high concentrations of potassium ions.
C)haploid proteins.
D)T tubules for the propagation of action potentials.
E)P granules of mRNA and protein.

Question 77

Select the choice that correctly associates the organ with its embryonic sources.

A)anterior pituitary gland-mesoderm and endoderm
B)thyroid gland-mesoderm and ectoderm
C)adrenal gland-ectoderm and mesoderm
D)skin-endoderm and mesoderm
E)brain-mesoderm and endoderm

Question 78

Which of the following is the anatomical axis that is largely symmetrical in both frogs and humans?

A)right to left
B)dorsal to ventral
C)anterior to posterior
D)animal to vegetal
E)rostral to caudal

Question 79

The embryonic precursor to the human spinal cord is the

A)notochord.
B)neural tube.
C)mesoderm.
D)archenteron.
E)set of bilateral somites.

Question 80

Which of the following is an adult organism that has fewer than 1000 cells?

A)chickens, Gallus domesticus
B)African clawed frogs, Xenopus laevis
C)humans, Homo sapiens
D)fruit flies, Drosophila melanogaster
E)nematodes, Caenorhabditis elegans