Deck 35: Treatment of Infections III: Antifungal and Antiparasitic Drugs

Question 1

Antifungal drugs are relatively safe when administered _____,but the risk of liver toxicity and other severe side effects increases substantially when these drugs are given _____.

A) topically; orally
B) orally; topically
C) subcutaneously; topically
D) intravenously; subcutaneously
E) systemically; locally

Answer 1

topically; orally

Question 2

Severe,systemic fungal infections are more likely if

A) patients are taking systemic doses of glucocorticoids
B) patients are taking systemic doses of other antibiotics
C) patients have AIDS
D) all the above are true
E) none of the above are true

Answer 2

all the above are true

Question 3

Many antifungal drugs selectively affect fungal cells rather than human cells by impairing the synthesis or function of specific sterols and polysaccharides that are located in the fungal cell

A) membrane
B) mitochondria
C) smooth endoplasmic reticulum
D) rough endoplasmic reticulum
E) DNA

Answer 3

membrane

Question 4

Cutaneous and mucocutaneous infections such as tinea (ringworm)infections and candidiasis are typically treated with

A) local or topical antibacterial drugs
B) local or topical antifungal drugs
C) systemic doses of antibacterial drugs
D) systemic doses of antifungal drugs
E) antiviral drugs

Question 5

Tapeworms (cestodes),roundworms (nematodes),and flukes (trematodes)are treated with

A) antifungal drugs
B) antiprotozoal drugs
C) anthelmintic drugs
D) antibacterial drugs
E) none of the above are true

Question 6

Although several different drugs are available to treat malaria,many of these drugs are ineffective in certain parts of the world because

A) malaria is difficult to diagnose accurately
B) the organism that causes malaria has become resistant to these drugs
C) antimalarial drugs must all be given by continuous intravenous infusion
D) all the above are true
E) none of the above are true