Question 1

Tissue transplantation between genetically identical twins is called:&#10;A) Allograft&#10;B) Isograft&#10;C) Homograft&#10;D) Xenograft&#10;E) Heterograft

Accepted Answer

Isograft transplantation involves tissue or organ transplantation between genetically identical individuals (such as twins) and is the best option for reducing the risk of rejection as there is no difference in the tissue antigens between the donor and recipient.

Question 2

Antibodies are produced by:&#10;A) B lymphocytes&#10;B) T-suppressor/cytotoxic lymphocytes&#10;C) Monocytes&#10;D) Plasma cells&#10;E) Eosinophils

Accepted Answer

Antibodies are produced by plasma cells, which are generated from B lymphocytes upon exposure to an antigen. T-suppressor/cytotoxic lymphocytes primarily function in cell-mediated immunity, while monocytes are involved in phagocytosis and immune regulation. Eosinophils are involved in the immune response against parasites and allergic reactions, but they do not produce antibodies.

Question 3

Which of the following is a common feature of AIDS?&#10;A) Burkitt's lymphoma&#10;B) Ankylosing spondylitis&#10;C) Sarcoidosis&#10;D) Kaposi's sarcoma&#10;E) Graft-versus-host reaction

Accepted Answer

Kaposi's sarcoma is a common feature of AIDS.

Question 4

Human immunodeficiency virus can be transmitted from an infected person by all the following routes except:&#10;A) Heterosexual intercourse&#10;B) Handshake&#10;C) Intravenous injection using infected needles&#10;D) Blood transfusions&#10;E) Transplacentally from mother to fetus

Accepted Answer

HIV cannot be transmitted through casual contact such as handshakes.

Question 5

Amyloid A formed in response to chronic infections is typically deposited in all the following organs except the:&#10;A) Brain&#10;B) Rectum&#10;C) Liver&#10;D) Kidney&#10;E) Adrenals

Accepted Answer

Amyloid A is typically deposited in various organs in response to chronic infections, but it does not typically deposit in the brain. The most common locations for amyloid A deposition are the liver, spleen, and kidneys, followed by the adrenal glands and gastrointestinal tract.

Question 6

For the diagnosis of AIDS,it is important to test the patient for antibodies to:&#10;A) Human papillomavirus (HPV)&#10;B) Epstein-Barr virus (EBV)&#10;C) Human immunodeficiency virus (HIV)&#10;D) Pneumocystis carinii&#10;E) Mycobacterium avium-intracellulare

Accepted Answer

The correct answer is HIV as it is the virus that causes AIDS. Testing for antibodies to the other viruses (HPV and EBV) and bacteria (Pneumocystis carinii and Mycobacterium avium-intracellulare) may be important for diagnosing other diseases or infections, but they are not necessary for diagnosing AIDS.

Question 7

Antinuclear antibodies (ANAs)are typically found in:&#10;A) Systemic lupus erythematosus&#10;B) AIDS&#10;C) Graft-versus-host reaction&#10;D) Sarcoidosis&#10;E) Isolated deficiency of IgA

Accepted Answer

ANAs are most commonly found in patients with systemic lupus erythematosus, an autoimmune disease. They can also be found in other autoimmune diseases such as rheumatoid arthritis, mixed connective tissue disease, and Sjogren's syndrome. ANAs are not typically associated with AIDS, graft-versus-host reaction, sarcoidosis, or isolated deficiency of IgA.

Question 8

Which set of lymphocytes is decreased the most in the blood of patients with AIDS?&#10;A) B lymphocytes&#10;B) T-helper lymphocytes&#10;C) T-suppressor/cytotoxic lymphocytes&#10;D) Natural killer cells&#10;E) Bone marrow stem cell precursor of lymphocytes

Accepted Answer

The answer of Which set of lymphocytes is decreased the...

Question 9

All the following are lymphokines produced by macrophages or T cells except:&#10;A) Interleukins&#10;B) Immunoglobulins&#10;C) Interferons&#10;D) Tumor necrosis factor&#10;E) Colony-stimulating factors

Accepted Answer

Immunoglobulins are not lymphokines produced by macrophages or T cells; they are produced by B cells. The other options (A, C, D, and E) are all lymphokines produced by macrophages or T cells.

Question 10

All the following are considered autoimmune diseases except:&#10;A) Systemic lupus erythematosus&#10;B) Multiple sclerosis&#10;C) Primary biliary cirrhosis&#10;D) Pemphigus vulgaris&#10;E) AIDS

Accepted Answer

While autoimmune diseases are caused by the immune system attacking healthy cells and tissues, AIDS (Acquired immunodeficiency syndrome) is a viral disease caused by the human immunodeficiency virus (HIV) that attacks the immune system itself, leaving the body vulnerable to a wide range of infections and diseases.

Question 11

All the following organs have been successfully transplanted in humans except:&#10;A) Brain&#10;B) Heart&#10;C) Pancreas&#10;D) Lungs&#10;E) Kidneys

Accepted Answer

The answer of All the following organs have been successfully...

Question 12

Autoimmune disease presenting with hyperthyroidism is called:&#10;A) Goodpasture's syndrome&#10;B) Sarcoidosis&#10;C) DiGeorge's disease&#10;D) Graves' disease&#10;E) Myasthenia gravis

Accepted Answer

The answer of Autoimmune disease presenting with hyperthyroidism is called:&#10;A)...

Question 13

Which of the following diseases is mediated by immunoglobulin E (IgE)attached to mast cells?&#10;A) Hay fever (allergic rhinitis)&#10;B) Systemic lupus erythematosus&#10;C) Sarcoidosis&#10;D) Polyarteritis nodosa&#10;E) Ankylosing spondylitis

Accepted Answer

The answer of Which of the following diseases is mediated...

Deck 3: Immunopathology